| Full name: netrin 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 4917 | HGNC ID: HGNC:8030 | Ensembl Gene: ENSG00000162068 | OMIM ID: 602349 |
| Drug and gene relationship at DGIdb | |||
Expression of NTN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NTN3 | 4917 | 207640_x_at | 0.0382 | 0.9194 | |
| GSE20347 | NTN3 | 4917 | 207640_x_at | -0.0665 | 0.2945 | |
| GSE23400 | NTN3 | 4917 | 207640_x_at | -0.0331 | 0.2425 | |
| GSE26886 | NTN3 | 4917 | 207640_x_at | 0.1430 | 0.1539 | |
| GSE29001 | NTN3 | 4917 | 207640_x_at | -0.0332 | 0.7994 | |
| GSE38129 | NTN3 | 4917 | 207640_x_at | -0.0429 | 0.4698 | |
| GSE45670 | NTN3 | 4917 | 207640_x_at | -0.0169 | 0.8840 | |
| GSE53622 | NTN3 | 4917 | 51654 | 0.0403 | 0.7483 | |
| GSE53624 | NTN3 | 4917 | 51654 | 0.3490 | 0.0000 | |
| GSE63941 | NTN3 | 4917 | 207640_x_at | -0.1007 | 0.5275 | |
| GSE77861 | NTN3 | 4917 | 207640_x_at | -0.0823 | 0.6072 | |
| GSE97050 | NTN3 | 4917 | A_33_P3271261 | -0.0624 | 0.8726 | |
| SRP133303 | NTN3 | 4917 | RNAseq | 0.9953 | 0.0096 | |
| TCGA | NTN3 | 4917 | RNAseq | 0.9151 | 0.0654 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NTN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NTN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NTN3 | 4917 | 5 | 5 | 20 | |
| GSE20123 | NTN3 | 4917 | 5 | 4 | 21 | |
| GSE43470 | NTN3 | 4917 | 4 | 7 | 32 | |
| GSE46452 | NTN3 | 4917 | 38 | 1 | 20 | |
| GSE47630 | NTN3 | 4917 | 13 | 6 | 21 | |
| GSE54993 | NTN3 | 4917 | 3 | 5 | 62 | |
| GSE54994 | NTN3 | 4917 | 5 | 9 | 39 | |
| GSE60625 | NTN3 | 4917 | 4 | 0 | 7 | |
| GSE74703 | NTN3 | 4917 | 4 | 5 | 27 | |
| GSE74704 | NTN3 | 4917 | 3 | 2 | 15 | |
| TCGA | NTN3 | 4917 | 20 | 13 | 63 |
Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.
Somatic mutations of NTN3:
Generating mutation plots.
Highly correlated genes for NTN3:
Showing top 20/349 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NTN3 | ARHGAP30 | 0.741514 | 3 | 0 | 3 |
| NTN3 | REXO1 | 0.714078 | 3 | 0 | 3 |
| NTN3 | CDH4 | 0.695675 | 5 | 0 | 5 |
| NTN3 | PYDC1 | 0.688892 | 3 | 0 | 3 |
| NTN3 | SLC2A11 | 0.686068 | 3 | 0 | 3 |
| NTN3 | ESPNL | 0.685478 | 3 | 0 | 3 |
| NTN3 | BSND | 0.663921 | 3 | 0 | 3 |
| NTN3 | HMCN2 | 0.66206 | 3 | 0 | 3 |
| NTN3 | SUN3 | 0.661389 | 3 | 0 | 3 |
| NTN3 | CELF4 | 0.659455 | 3 | 0 | 3 |
| NTN3 | FSCN2 | 0.654348 | 4 | 0 | 4 |
| NTN3 | VGF | 0.654017 | 5 | 0 | 4 |
| NTN3 | CDH23 | 0.64789 | 4 | 0 | 4 |
| NTN3 | PROCA1 | 0.644783 | 3 | 0 | 3 |
| NTN3 | ALOX15 | 0.64254 | 3 | 0 | 3 |
| NTN3 | MORN1 | 0.642138 | 6 | 0 | 6 |
| NTN3 | REG3A | 0.642112 | 5 | 0 | 4 |
| NTN3 | EFCAB13 | 0.639475 | 4 | 0 | 3 |
| NTN3 | GPD1 | 0.639406 | 4 | 0 | 4 |
| NTN3 | JSRP1 | 0.637437 | 4 | 0 | 3 |
For details and further investigation, click here
