| Full name: FERM domain containing 5 | Alias Symbol: MGC14161 | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 84978 | HGNC ID: HGNC:28214 | Ensembl Gene: ENSG00000171877 | OMIM ID: 616309 |
| Drug and gene relationship at DGIdb | |||
Expression of FRMD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRMD5 | 84978 | 1569470_a_at | 0.0265 | 0.9513 | |
| GSE26886 | FRMD5 | 84978 | 1569470_a_at | 0.4951 | 0.0048 | |
| GSE45670 | FRMD5 | 84978 | 1569470_a_at | 0.0947 | 0.3711 | |
| GSE53622 | FRMD5 | 84978 | 89622 | 0.4440 | 0.0038 | |
| GSE53624 | FRMD5 | 84978 | 89622 | 0.8162 | 0.0000 | |
| GSE63941 | FRMD5 | 84978 | 230831_at | 2.1099 | 0.0160 | |
| GSE77861 | FRMD5 | 84978 | 1569470_a_at | -0.0410 | 0.8230 | |
| GSE97050 | FRMD5 | 84978 | A_23_P26037 | 0.3150 | 0.3193 | |
| SRP064894 | FRMD5 | 84978 | RNAseq | 1.8015 | 0.0000 | |
| SRP133303 | FRMD5 | 84978 | RNAseq | 0.8833 | 0.0004 | |
| SRP193095 | FRMD5 | 84978 | RNAseq | 1.4739 | 0.0000 | |
| SRP219564 | FRMD5 | 84978 | RNAseq | 0.7799 | 0.3514 | |
| TCGA | FRMD5 | 84978 | RNAseq | -1.1147 | 0.0021 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by FRMD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRMD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRMD5 | 84978 | 3 | 4 | 23 | |
| GSE20123 | FRMD5 | 84978 | 3 | 5 | 22 | |
| GSE43470 | FRMD5 | 84978 | 3 | 4 | 36 | |
| GSE46452 | FRMD5 | 84978 | 3 | 7 | 49 | |
| GSE47630 | FRMD5 | 84978 | 8 | 10 | 22 | |
| GSE54993 | FRMD5 | 84978 | 4 | 6 | 60 | |
| GSE54994 | FRMD5 | 84978 | 5 | 7 | 41 | |
| GSE60625 | FRMD5 | 84978 | 4 | 0 | 7 | |
| GSE74703 | FRMD5 | 84978 | 3 | 3 | 30 | |
| GSE74704 | FRMD5 | 84978 | 2 | 2 | 16 | |
| TCGA | FRMD5 | 84978 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 65; Total Number of normals: 373.
Somatic mutations of FRMD5:
Generating mutation plots.
Highly correlated genes for FRMD5:
Showing top 20/168 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRMD5 | GGT5 | 0.702589 | 4 | 0 | 3 |
| FRMD5 | ZFP92 | 0.687587 | 3 | 0 | 3 |
| FRMD5 | FAM167B | 0.670115 | 3 | 0 | 3 |
| FRMD5 | ROPN1L | 0.666224 | 4 | 0 | 3 |
| FRMD5 | ADORA2B | 0.665353 | 3 | 0 | 3 |
| FRMD5 | GSX1 | 0.66442 | 3 | 0 | 3 |
| FRMD5 | KCNS1 | 0.661231 | 4 | 0 | 4 |
| FRMD5 | KLHL11 | 0.65878 | 4 | 0 | 3 |
| FRMD5 | EAF2 | 0.65878 | 3 | 0 | 3 |
| FRMD5 | DOC2A | 0.658518 | 3 | 0 | 3 |
| FRMD5 | EPN1 | 0.648719 | 3 | 0 | 3 |
| FRMD5 | CRYBA1 | 0.642043 | 3 | 0 | 3 |
| FRMD5 | BLM | 0.63589 | 4 | 0 | 3 |
| FRMD5 | TMEM121 | 0.628367 | 4 | 0 | 3 |
| FRMD5 | TIMP1 | 0.62702 | 4 | 0 | 4 |
| FRMD5 | ZNF771 | 0.626314 | 4 | 0 | 3 |
| FRMD5 | GPR19 | 0.622792 | 4 | 0 | 3 |
| FRMD5 | ASIC1 | 0.619975 | 3 | 0 | 3 |
| FRMD5 | LTA | 0.618767 | 3 | 0 | 3 |
| FRMD5 | CCR10 | 0.618145 | 4 | 0 | 4 |
For details and further investigation, click here
