| Full name: nudix hydrolase 12 | Alias Symbol: DKFZP761I172 | ||
| Type: protein-coding gene | Cytoband: 5q21.2 | ||
| Entrez ID: 83594 | HGNC ID: HGNC:18826 | Ensembl Gene: ENSG00000112874 | OMIM ID: 609232 |
| Drug and gene relationship at DGIdb | |||
Expression of NUDT12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT12 | 83594 | 223535_at | -0.7160 | 0.2074 | |
| GSE26886 | NUDT12 | 83594 | 223535_at | -1.0927 | 0.0096 | |
| GSE45670 | NUDT12 | 83594 | 223535_at | -0.6192 | 0.0226 | |
| GSE53622 | NUDT12 | 83594 | 40589 | -1.3030 | 0.0000 | |
| GSE53624 | NUDT12 | 83594 | 40589 | -1.0869 | 0.0000 | |
| GSE63941 | NUDT12 | 83594 | 223535_at | -1.3908 | 0.0424 | |
| GSE77861 | NUDT12 | 83594 | 223535_at | -0.8199 | 0.0100 | |
| SRP007169 | NUDT12 | 83594 | RNAseq | -1.7661 | 0.0249 | |
| SRP008496 | NUDT12 | 83594 | RNAseq | -1.1442 | 0.0079 | |
| SRP064894 | NUDT12 | 83594 | RNAseq | -0.3869 | 0.0714 | |
| SRP133303 | NUDT12 | 83594 | RNAseq | -0.1358 | 0.6623 | |
| SRP159526 | NUDT12 | 83594 | RNAseq | -0.7873 | 0.0186 | |
| SRP193095 | NUDT12 | 83594 | RNAseq | -1.3557 | 0.0000 | |
| SRP219564 | NUDT12 | 83594 | RNAseq | -1.2668 | 0.0538 | |
| TCGA | NUDT12 | 83594 | RNAseq | -0.4742 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by NUDT12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT12 | 83594 | 1 | 13 | 16 | |
| GSE20123 | NUDT12 | 83594 | 1 | 13 | 16 | |
| GSE43470 | NUDT12 | 83594 | 3 | 9 | 31 | |
| GSE46452 | NUDT12 | 83594 | 0 | 28 | 31 | |
| GSE47630 | NUDT12 | 83594 | 0 | 20 | 20 | |
| GSE54993 | NUDT12 | 83594 | 9 | 1 | 60 | |
| GSE54994 | NUDT12 | 83594 | 1 | 17 | 35 | |
| GSE60625 | NUDT12 | 83594 | 0 | 0 | 11 | |
| GSE74703 | NUDT12 | 83594 | 2 | 7 | 27 | |
| GSE74704 | NUDT12 | 83594 | 1 | 7 | 12 | |
| TCGA | NUDT12 | 83594 | 2 | 44 | 50 |
Total number of gains: 20; Total number of losses: 159; Total Number of normals: 309.
Somatic mutations of NUDT12:
Generating mutation plots.
Highly correlated genes for NUDT12:
Showing top 20/791 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT12 | YTHDC2 | 0.715669 | 6 | 0 | 5 |
| NUDT12 | TMEM61 | 0.7045 | 3 | 0 | 3 |
| NUDT12 | TTYH1 | 0.699388 | 3 | 0 | 3 |
| NUDT12 | RAB10 | 0.687222 | 5 | 0 | 5 |
| NUDT12 | NPAS2 | 0.684897 | 3 | 0 | 3 |
| NUDT12 | CLOCK | 0.682415 | 5 | 0 | 5 |
| NUDT12 | NDFIP2 | 0.681998 | 3 | 0 | 3 |
| NUDT12 | KIAA0232 | 0.681711 | 5 | 0 | 5 |
| NUDT12 | STAU2 | 0.678696 | 6 | 0 | 5 |
| NUDT12 | COBLL1 | 0.671427 | 6 | 0 | 5 |
| NUDT12 | UFL1 | 0.669683 | 7 | 0 | 6 |
| NUDT12 | FCHO2 | 0.667898 | 6 | 0 | 6 |
| NUDT12 | STX7 | 0.665781 | 5 | 0 | 5 |
| NUDT12 | FBXO3 | 0.66558 | 5 | 0 | 5 |
| NUDT12 | C12orf29 | 0.664719 | 6 | 0 | 6 |
| NUDT12 | ELK3 | 0.664123 | 4 | 0 | 3 |
| NUDT12 | VPS13D | 0.66346 | 5 | 0 | 5 |
| NUDT12 | MAML3 | 0.663052 | 3 | 0 | 3 |
| NUDT12 | SLTM | 0.660884 | 4 | 0 | 4 |
| NUDT12 | LRRK2 | 0.66086 | 6 | 0 | 6 |
For details and further investigation, click here
