| Full name: staufen double-stranded RNA binding protein 2 | Alias Symbol: 39K2 | ||
| Type: protein-coding gene | Cytoband: 8q21.11 | ||
| Entrez ID: 27067 | HGNC ID: HGNC:11371 | Ensembl Gene: ENSG00000040341 | OMIM ID: 605920 |
| Drug and gene relationship at DGIdb | |||
Expression of STAU2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STAU2 | 27067 | 204226_at | -0.5293 | 0.2518 | |
| GSE20347 | STAU2 | 27067 | 204226_at | -0.7500 | 0.0194 | |
| GSE23400 | STAU2 | 27067 | 204226_at | -0.4316 | 0.0000 | |
| GSE26886 | STAU2 | 27067 | 204226_at | -1.6872 | 0.0000 | |
| GSE29001 | STAU2 | 27067 | 204226_at | -0.8001 | 0.0415 | |
| GSE38129 | STAU2 | 27067 | 204226_at | -0.5953 | 0.0128 | |
| GSE45670 | STAU2 | 27067 | 204226_at | -0.4178 | 0.1278 | |
| GSE53622 | STAU2 | 27067 | 155537 | -0.7388 | 0.0000 | |
| GSE53624 | STAU2 | 27067 | 155537 | -1.0125 | 0.0000 | |
| GSE63941 | STAU2 | 27067 | 227179_at | -0.2099 | 0.7495 | |
| GSE77861 | STAU2 | 27067 | 204226_at | -1.0089 | 0.0063 | |
| GSE97050 | STAU2 | A_21_P0013825 | -0.1358 | 0.6505 | ||
| SRP007169 | STAU2 | 27067 | RNAseq | -1.1180 | 0.0053 | |
| SRP008496 | STAU2 | 27067 | RNAseq | -1.1307 | 0.0000 | |
| SRP064894 | STAU2 | 27067 | RNAseq | -0.2823 | 0.1252 | |
| SRP133303 | STAU2 | 27067 | RNAseq | -0.3865 | 0.0560 | |
| SRP159526 | STAU2 | 27067 | RNAseq | -0.4319 | 0.2245 | |
| SRP193095 | STAU2 | 27067 | RNAseq | -0.5272 | 0.0002 | |
| SRP219564 | STAU2 | 27067 | RNAseq | -0.7296 | 0.0677 | |
| TCGA | STAU2 | 27067 | RNAseq | -0.0299 | 0.5911 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by STAU2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STAU2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STAU2 | 27067 | 15 | 0 | 15 | |
| GSE20123 | STAU2 | 27067 | 16 | 0 | 14 | |
| GSE43470 | STAU2 | 27067 | 19 | 1 | 23 | |
| GSE46452 | STAU2 | 27067 | 21 | 1 | 37 | |
| GSE47630 | STAU2 | 27067 | 23 | 0 | 17 | |
| GSE54993 | STAU2 | 27067 | 0 | 19 | 51 | |
| GSE54994 | STAU2 | 27067 | 30 | 0 | 23 | |
| GSE60625 | STAU2 | 27067 | 0 | 4 | 7 | |
| GSE74703 | STAU2 | 27067 | 16 | 1 | 19 | |
| GSE74704 | STAU2 | 27067 | 11 | 0 | 9 | |
| TCGA | STAU2 | 27067 | 50 | 2 | 44 |
Total number of gains: 201; Total number of losses: 28; Total Number of normals: 259.
Somatic mutations of STAU2:
Generating mutation plots.
Highly correlated genes for STAU2:
Showing top 20/1523 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STAU2 | CNOT4 | 0.838518 | 3 | 0 | 3 |
| STAU2 | WBP2 | 0.7758 | 3 | 0 | 3 |
| STAU2 | RBM20 | 0.772229 | 4 | 0 | 4 |
| STAU2 | USP32 | 0.767724 | 3 | 0 | 3 |
| STAU2 | MPP7 | 0.760322 | 7 | 0 | 7 |
| STAU2 | HDHD2 | 0.754691 | 4 | 0 | 4 |
| STAU2 | TYSND1 | 0.752678 | 3 | 0 | 3 |
| STAU2 | FCHO2 | 0.75104 | 7 | 0 | 7 |
| STAU2 | CYSRT1 | 0.747785 | 6 | 0 | 6 |
| STAU2 | ZNF585A | 0.747082 | 3 | 0 | 3 |
| STAU2 | C2CD2 | 0.746702 | 3 | 0 | 3 |
| STAU2 | GCC2 | 0.742212 | 3 | 0 | 3 |
| STAU2 | ULK3 | 0.74043 | 7 | 0 | 7 |
| STAU2 | SPAG17 | 0.73564 | 4 | 0 | 4 |
| STAU2 | MUC15 | 0.733873 | 6 | 0 | 6 |
| STAU2 | ARF4 | 0.733323 | 4 | 0 | 4 |
| STAU2 | FAM3D | 0.732635 | 6 | 0 | 6 |
| STAU2 | CAPN14 | 0.732616 | 6 | 0 | 6 |
| STAU2 | ZCCHC9 | 0.732329 | 4 | 0 | 3 |
| STAU2 | CCNYL1 | 0.729136 | 6 | 0 | 5 |
For details and further investigation, click here
