| Full name: vacuolar protein sorting 13 homolog D | Alias Symbol: FLJ10619|KIAA0453 | ||
| Type: protein-coding gene | Cytoband: 1p36.22-p36.21 | ||
| Entrez ID: 55187 | HGNC ID: HGNC:23595 | Ensembl Gene: ENSG00000048707 | OMIM ID: 608877 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of VPS13D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS13D | 55187 | 212323_s_at | -0.4881 | 0.1219 | |
| GSE20347 | VPS13D | 55187 | 212323_s_at | -1.1028 | 0.0000 | |
| GSE23400 | VPS13D | 55187 | 212323_s_at | -0.6599 | 0.0000 | |
| GSE26886 | VPS13D | 55187 | 212323_s_at | -0.7539 | 0.0129 | |
| GSE29001 | VPS13D | 55187 | 212323_s_at | -0.7784 | 0.0007 | |
| GSE38129 | VPS13D | 55187 | 212323_s_at | -0.9093 | 0.0000 | |
| GSE45670 | VPS13D | 55187 | 212323_s_at | -0.3608 | 0.0621 | |
| GSE53622 | VPS13D | 55187 | 15963 | -1.6011 | 0.0000 | |
| GSE53624 | VPS13D | 55187 | 15963 | -1.1851 | 0.0000 | |
| GSE63941 | VPS13D | 55187 | 212323_s_at | 0.0836 | 0.8358 | |
| GSE77861 | VPS13D | 55187 | 212323_s_at | -0.9139 | 0.0007 | |
| GSE97050 | VPS13D | 55187 | A_23_P364837 | -0.4897 | 0.1556 | |
| SRP007169 | VPS13D | 55187 | RNAseq | -1.0861 | 0.0086 | |
| SRP008496 | VPS13D | 55187 | RNAseq | -0.9500 | 0.0001 | |
| SRP064894 | VPS13D | 55187 | RNAseq | -0.8647 | 0.0000 | |
| SRP133303 | VPS13D | 55187 | RNAseq | -0.8174 | 0.0000 | |
| SRP159526 | VPS13D | 55187 | RNAseq | -1.1981 | 0.0000 | |
| SRP193095 | VPS13D | 55187 | RNAseq | -0.4888 | 0.0007 | |
| SRP219564 | VPS13D | 55187 | RNAseq | -0.9460 | 0.0052 | |
| TCGA | VPS13D | 55187 | RNAseq | -0.2608 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by VPS13D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS13D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS13D | 55187 | 0 | 5 | 25 | |
| GSE20123 | VPS13D | 55187 | 0 | 4 | 26 | |
| GSE43470 | VPS13D | 55187 | 4 | 6 | 33 | |
| GSE46452 | VPS13D | 55187 | 7 | 1 | 51 | |
| GSE47630 | VPS13D | 55187 | 8 | 4 | 28 | |
| GSE54993 | VPS13D | 55187 | 3 | 1 | 66 | |
| GSE54994 | VPS13D | 55187 | 11 | 4 | 38 | |
| GSE60625 | VPS13D | 55187 | 0 | 0 | 11 | |
| GSE74703 | VPS13D | 55187 | 3 | 4 | 29 | |
| GSE74704 | VPS13D | 55187 | 0 | 0 | 20 | |
| TCGA | VPS13D | 55187 | 10 | 23 | 63 |
Total number of gains: 46; Total number of losses: 52; Total Number of normals: 390.
Somatic mutations of VPS13D:
Generating mutation plots.
Highly correlated genes for VPS13D:
Showing top 20/1687 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS13D | ARHGEF10L | 0.81593 | 11 | 0 | 11 |
| VPS13D | CLEC3B | 0.808054 | 3 | 0 | 3 |
| VPS13D | CPEB3 | 0.785389 | 10 | 0 | 9 |
| VPS13D | RMND5B | 0.771563 | 11 | 0 | 10 |
| VPS13D | VAV3 | 0.768526 | 8 | 0 | 8 |
| VPS13D | ACOX3 | 0.760603 | 11 | 0 | 10 |
| VPS13D | TPCN1 | 0.759372 | 11 | 0 | 11 |
| VPS13D | CNPPD1 | 0.753991 | 10 | 0 | 10 |
| VPS13D | RAB5A | 0.750575 | 11 | 0 | 11 |
| VPS13D | SASH1 | 0.747258 | 11 | 0 | 11 |
| VPS13D | CYP2J2 | 0.746119 | 10 | 0 | 10 |
| VPS13D | SORT1 | 0.745841 | 11 | 0 | 11 |
| VPS13D | ANO10 | 0.745388 | 10 | 0 | 10 |
| VPS13D | KIAA1211L | 0.743269 | 6 | 0 | 6 |
| VPS13D | GPD1L | 0.737944 | 12 | 0 | 12 |
| VPS13D | PI16 | 0.737406 | 3 | 0 | 3 |
| VPS13D | SCNN1B | 0.73648 | 11 | 0 | 10 |
| VPS13D | LRRFIP2 | 0.734302 | 11 | 0 | 11 |
| VPS13D | MPP7 | 0.733745 | 7 | 0 | 6 |
| VPS13D | MGST2 | 0.733425 | 11 | 0 | 10 |
For details and further investigation, click here
