| Full name: syntaxin 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q23.2 | ||
| Entrez ID: 8417 | HGNC ID: HGNC:11442 | Ensembl Gene: ENSG00000079950 | OMIM ID: 603217 |
| Drug and gene relationship at DGIdb | |||
Expression of STX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX7 | 8417 | 212632_at | -0.7818 | 0.0756 | |
| GSE20347 | STX7 | 8417 | 212631_at | -1.0568 | 0.0000 | |
| GSE23400 | STX7 | 8417 | 212631_at | -0.5385 | 0.0000 | |
| GSE26886 | STX7 | 8417 | 212631_at | -1.3438 | 0.0000 | |
| GSE29001 | STX7 | 8417 | 212631_at | -0.9655 | 0.0000 | |
| GSE38129 | STX7 | 8417 | 212632_at | -0.9135 | 0.0000 | |
| GSE45670 | STX7 | 8417 | 212632_at | -0.7371 | 0.0000 | |
| GSE53622 | STX7 | 8417 | 3597 | -0.7276 | 0.0000 | |
| GSE53624 | STX7 | 8417 | 3597 | -0.9533 | 0.0000 | |
| GSE63941 | STX7 | 8417 | 212631_at | -0.3359 | 0.4739 | |
| GSE77861 | STX7 | 8417 | 212631_at | -0.8787 | 0.0019 | |
| GSE97050 | STX7 | 8417 | A_23_P303260 | -0.4303 | 0.1323 | |
| SRP007169 | STX7 | 8417 | RNAseq | -1.3633 | 0.0000 | |
| SRP008496 | STX7 | 8417 | RNAseq | -1.5265 | 0.0000 | |
| SRP064894 | STX7 | 8417 | RNAseq | -0.7761 | 0.0006 | |
| SRP133303 | STX7 | 8417 | RNAseq | -0.4957 | 0.0017 | |
| SRP159526 | STX7 | 8417 | RNAseq | -1.2340 | 0.0003 | |
| SRP193095 | STX7 | 8417 | RNAseq | -0.9654 | 0.0000 | |
| SRP219564 | STX7 | 8417 | RNAseq | -0.8803 | 0.0112 | |
| TCGA | STX7 | 8417 | RNAseq | -0.2405 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by STX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX7 | 8417 | 3 | 4 | 23 | |
| GSE20123 | STX7 | 8417 | 3 | 3 | 24 | |
| GSE43470 | STX7 | 8417 | 5 | 0 | 38 | |
| GSE46452 | STX7 | 8417 | 2 | 11 | 46 | |
| GSE47630 | STX7 | 8417 | 9 | 4 | 27 | |
| GSE54993 | STX7 | 8417 | 3 | 2 | 65 | |
| GSE54994 | STX7 | 8417 | 9 | 7 | 37 | |
| GSE60625 | STX7 | 8417 | 0 | 1 | 10 | |
| GSE74703 | STX7 | 8417 | 4 | 0 | 32 | |
| GSE74704 | STX7 | 8417 | 1 | 1 | 18 | |
| TCGA | STX7 | 8417 | 11 | 18 | 67 |
Total number of gains: 50; Total number of losses: 51; Total Number of normals: 387.
Somatic mutations of STX7:
Generating mutation plots.
Highly correlated genes for STX7:
Showing top 20/1408 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX7 | TMEM45B | 0.798748 | 3 | 0 | 3 |
| STX7 | RAP1A | 0.755819 | 10 | 0 | 10 |
| STX7 | PARD6B | 0.754701 | 3 | 0 | 3 |
| STX7 | SNX9 | 0.754108 | 7 | 0 | 7 |
| STX7 | SPNS2 | 0.753916 | 3 | 0 | 3 |
| STX7 | ANGPTL1 | 0.745738 | 4 | 0 | 4 |
| STX7 | MPC1 | 0.7369 | 10 | 0 | 10 |
| STX7 | EIF4E3 | 0.735117 | 7 | 0 | 6 |
| STX7 | HDHD2 | 0.735067 | 4 | 0 | 4 |
| STX7 | FBXO8 | 0.732531 | 7 | 0 | 6 |
| STX7 | SNORA68 | 0.73206 | 4 | 0 | 4 |
| STX7 | KAT2B | 0.72536 | 11 | 0 | 10 |
| STX7 | AK9 | 0.719968 | 6 | 0 | 6 |
| STX7 | CGNL1 | 0.715776 | 6 | 0 | 6 |
| STX7 | GPD1L | 0.71385 | 11 | 0 | 10 |
| STX7 | AK3 | 0.713479 | 6 | 0 | 6 |
| STX7 | UBL3 | 0.708994 | 11 | 0 | 10 |
| STX7 | SDR16C5 | 0.707107 | 3 | 0 | 3 |
| STX7 | ZNF662 | 0.707058 | 6 | 0 | 6 |
| STX7 | ARHGAP27 | 0.70645 | 4 | 0 | 4 |
For details and further investigation, click here
