| Full name: protein O-mannosyltransferase 1 | Alias Symbol: LGMD2K | ||
| Type: protein-coding gene | Cytoband: 9q34.13 | ||
| Entrez ID: 10585 | HGNC ID: HGNC:9202 | Ensembl Gene: ENSG00000130714 | OMIM ID: 607423 |
| Drug and gene relationship at DGIdb | |||
Expression of POMT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POMT1 | 10585 | 218476_at | 0.2052 | 0.7120 | |
| GSE20347 | POMT1 | 10585 | 218476_at | -0.0509 | 0.6918 | |
| GSE23400 | POMT1 | 10585 | 218476_at | -0.0718 | 0.2020 | |
| GSE26886 | POMT1 | 10585 | 218476_at | 0.0571 | 0.8140 | |
| GSE29001 | POMT1 | 10585 | 218476_at | 0.1681 | 0.5752 | |
| GSE38129 | POMT1 | 10585 | 218476_at | -0.1271 | 0.2244 | |
| GSE45670 | POMT1 | 10585 | 218476_at | -0.2200 | 0.0856 | |
| GSE53622 | POMT1 | 10585 | 7072 | -0.2006 | 0.0200 | |
| GSE53624 | POMT1 | 10585 | 7072 | 0.0530 | 0.4850 | |
| GSE63941 | POMT1 | 10585 | 218476_at | -1.0918 | 0.0607 | |
| GSE77861 | POMT1 | 10585 | 218476_at | -0.1248 | 0.4803 | |
| GSE97050 | POMT1 | 10585 | A_23_P146354 | -0.1764 | 0.6162 | |
| SRP007169 | POMT1 | 10585 | RNAseq | 0.1815 | 0.7291 | |
| SRP064894 | POMT1 | 10585 | RNAseq | 0.4871 | 0.0261 | |
| SRP133303 | POMT1 | 10585 | RNAseq | -0.1610 | 0.5430 | |
| SRP159526 | POMT1 | 10585 | RNAseq | 0.5855 | 0.1387 | |
| SRP193095 | POMT1 | 10585 | RNAseq | 0.1144 | 0.2995 | |
| SRP219564 | POMT1 | 10585 | RNAseq | 0.0237 | 0.9604 | |
| TCGA | POMT1 | 10585 | RNAseq | -0.2147 | 0.0029 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by POMT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POMT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POMT1 | 10585 | 6 | 9 | 15 | |
| GSE20123 | POMT1 | 10585 | 6 | 9 | 15 | |
| GSE43470 | POMT1 | 10585 | 5 | 7 | 31 | |
| GSE46452 | POMT1 | 10585 | 6 | 13 | 40 | |
| GSE47630 | POMT1 | 10585 | 3 | 16 | 21 | |
| GSE54993 | POMT1 | 10585 | 3 | 3 | 64 | |
| GSE54994 | POMT1 | 10585 | 12 | 9 | 32 | |
| GSE60625 | POMT1 | 10585 | 0 | 0 | 11 | |
| GSE74703 | POMT1 | 10585 | 5 | 5 | 26 | |
| GSE74704 | POMT1 | 10585 | 3 | 7 | 10 | |
| TCGA | POMT1 | 10585 | 28 | 26 | 42 |
Total number of gains: 77; Total number of losses: 104; Total Number of normals: 307.
Somatic mutations of POMT1:
Generating mutation plots.
Highly correlated genes for POMT1:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POMT1 | NUDT3 | 0.772767 | 3 | 0 | 3 |
| POMT1 | AKAP17A | 0.739113 | 3 | 0 | 3 |
| POMT1 | CD99 | 0.727751 | 3 | 0 | 3 |
| POMT1 | SLC39A13 | 0.724052 | 3 | 0 | 3 |
| POMT1 | GNB4 | 0.691549 | 4 | 0 | 4 |
| POMT1 | TNFSF4 | 0.689206 | 3 | 0 | 3 |
| POMT1 | WDFY3 | 0.686321 | 3 | 0 | 3 |
| POMT1 | MRC2 | 0.681601 | 4 | 0 | 4 |
| POMT1 | ZNF805 | 0.679936 | 3 | 0 | 3 |
| POMT1 | GNPAT | 0.679643 | 3 | 0 | 3 |
| POMT1 | SAT2 | 0.679133 | 3 | 0 | 3 |
| POMT1 | ZNF691 | 0.67889 | 3 | 0 | 3 |
| POMT1 | CNIH3 | 0.673351 | 3 | 0 | 3 |
| POMT1 | HSDL1 | 0.672972 | 4 | 0 | 3 |
| POMT1 | IGIP | 0.669077 | 4 | 0 | 3 |
| POMT1 | SUGP2 | 0.663932 | 4 | 0 | 4 |
| POMT1 | UAP1 | 0.662252 | 3 | 0 | 3 |
| POMT1 | SPIRE2 | 0.655234 | 3 | 0 | 3 |
| POMT1 | MAPKAPK5 | 0.653928 | 3 | 0 | 3 |
| POMT1 | WFDC1 | 0.651344 | 3 | 0 | 3 |
For details and further investigation, click here
