| Full name: nucleoporin 98 | Alias Symbol: NUP96 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 4928 | HGNC ID: HGNC:8068 | Ensembl Gene: ENSG00000110713 | OMIM ID: 601021 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUP98:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP98 | 4928 | 210793_s_at | 0.1795 | 0.8253 | |
| GSE20347 | NUP98 | 4928 | 210793_s_at | -0.3369 | 0.0803 | |
| GSE23400 | NUP98 | 4928 | 203195_s_at | 0.2075 | 0.0003 | |
| GSE26886 | NUP98 | 4928 | 210793_s_at | -0.2377 | 0.3335 | |
| GSE29001 | NUP98 | 4928 | 210793_s_at | -0.1518 | 0.6069 | |
| GSE38129 | NUP98 | 4928 | 210793_s_at | -0.0019 | 0.9926 | |
| GSE45670 | NUP98 | 4928 | 210793_s_at | -0.0017 | 0.9948 | |
| GSE53622 | NUP98 | 4928 | 144442 | 0.0347 | 0.5230 | |
| GSE53624 | NUP98 | 4928 | 144442 | 0.1796 | 0.0005 | |
| GSE63941 | NUP98 | 4928 | 203194_s_at | 1.4100 | 0.0006 | |
| GSE77861 | NUP98 | 4928 | 203195_s_at | 0.1709 | 0.4591 | |
| GSE97050 | NUP98 | 4928 | A_23_P203586 | -0.0291 | 0.9114 | |
| SRP007169 | NUP98 | 4928 | RNAseq | 0.0172 | 0.9647 | |
| SRP008496 | NUP98 | 4928 | RNAseq | 0.2281 | 0.3873 | |
| SRP064894 | NUP98 | 4928 | RNAseq | -0.2781 | 0.1282 | |
| SRP133303 | NUP98 | 4928 | RNAseq | 0.1030 | 0.3300 | |
| SRP159526 | NUP98 | 4928 | RNAseq | -0.2118 | 0.4595 | |
| SRP193095 | NUP98 | 4928 | RNAseq | 0.0588 | 0.4345 | |
| SRP219564 | NUP98 | 4928 | RNAseq | -0.0972 | 0.6405 | |
| TCGA | NUP98 | 4928 | RNAseq | 0.0202 | 0.6292 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NUP98 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP98:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP98 | 4928 | 1 | 12 | 17 | |
| GSE20123 | NUP98 | 4928 | 1 | 11 | 18 | |
| GSE43470 | NUP98 | 4928 | 1 | 9 | 33 | |
| GSE46452 | NUP98 | 4928 | 7 | 8 | 44 | |
| GSE47630 | NUP98 | 4928 | 4 | 12 | 24 | |
| GSE54993 | NUP98 | 4928 | 3 | 1 | 66 | |
| GSE54994 | NUP98 | 4928 | 1 | 14 | 38 | |
| GSE60625 | NUP98 | 4928 | 0 | 0 | 11 | |
| GSE74703 | NUP98 | 4928 | 1 | 8 | 27 | |
| GSE74704 | NUP98 | 4928 | 0 | 8 | 12 | |
| TCGA | NUP98 | 4928 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of NUP98:
Generating mutation plots.
Highly correlated genes for NUP98:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP98 | TMEM102 | 0.76867 | 3 | 0 | 3 |
| NUP98 | GEMIN2 | 0.69623 | 4 | 0 | 3 |
| NUP98 | STK11 | 0.6775 | 3 | 0 | 3 |
| NUP98 | RAPGEF5 | 0.663303 | 3 | 0 | 3 |
| NUP98 | LAS1L | 0.662598 | 3 | 0 | 3 |
| NUP98 | C7orf26 | 0.660057 | 3 | 0 | 3 |
| NUP98 | ZNF687 | 0.658796 | 5 | 0 | 4 |
| NUP98 | CDK16 | 0.650565 | 5 | 0 | 5 |
| NUP98 | GINS2 | 0.646896 | 3 | 0 | 3 |
| NUP98 | ANGPTL3 | 0.646393 | 3 | 0 | 3 |
| NUP98 | PLA2G4F | 0.644298 | 3 | 0 | 3 |
| NUP98 | NUP62CL | 0.636018 | 4 | 0 | 3 |
| NUP98 | POC1A | 0.634249 | 4 | 0 | 3 |
| NUP98 | PARS2 | 0.632796 | 4 | 0 | 3 |
| NUP98 | MAFG | 0.632076 | 3 | 0 | 3 |
| NUP98 | WDR83 | 0.631145 | 4 | 0 | 3 |
| NUP98 | MRPS16 | 0.628649 | 4 | 0 | 3 |
| NUP98 | LIPE | 0.627546 | 4 | 0 | 4 |
| NUP98 | KLF5 | 0.627255 | 3 | 0 | 3 |
| NUP98 | SDCCAG8 | 0.623083 | 4 | 0 | 3 |
For details and further investigation, click here
