| Full name: nuclear protein 1, transcriptional regulator | Alias Symbol: COM1|p8 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 26471 | HGNC ID: HGNC:29990 | Ensembl Gene: ENSG00000176046 | OMIM ID: 614812 |
| Drug and gene relationship at DGIdb | |||
Expression of NUPR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUPR1 | 26471 | 209230_s_at | -0.6942 | 0.3298 | |
| GSE20347 | NUPR1 | 26471 | 209230_s_at | 0.3847 | 0.2059 | |
| GSE23400 | NUPR1 | 26471 | 209230_s_at | -0.0630 | 0.5720 | |
| GSE26886 | NUPR1 | 26471 | 209230_s_at | 0.5129 | 0.2204 | |
| GSE29001 | NUPR1 | 26471 | 209230_s_at | 0.4277 | 0.2812 | |
| GSE38129 | NUPR1 | 26471 | 209230_s_at | 0.1172 | 0.7183 | |
| GSE45670 | NUPR1 | 26471 | 209230_s_at | -0.2904 | 0.4158 | |
| GSE53622 | NUPR1 | 26471 | 26636 | -0.1523 | 0.2968 | |
| GSE53624 | NUPR1 | 26471 | 26636 | 0.2002 | 0.0234 | |
| GSE63941 | NUPR1 | 26471 | 209230_s_at | -2.1897 | 0.1944 | |
| GSE77861 | NUPR1 | 26471 | 209230_s_at | 0.0464 | 0.9354 | |
| GSE97050 | NUPR1 | 26471 | A_24_P270728 | -0.6994 | 0.1299 | |
| SRP007169 | NUPR1 | 26471 | RNAseq | 0.4525 | 0.3927 | |
| SRP008496 | NUPR1 | 26471 | RNAseq | 0.6656 | 0.0723 | |
| SRP064894 | NUPR1 | 26471 | RNAseq | 0.5437 | 0.2457 | |
| SRP133303 | NUPR1 | 26471 | RNAseq | 0.0998 | 0.7091 | |
| SRP159526 | NUPR1 | 26471 | RNAseq | -0.1274 | 0.7663 | |
| SRP193095 | NUPR1 | 26471 | RNAseq | 0.1998 | 0.3259 | |
| SRP219564 | NUPR1 | 26471 | RNAseq | -0.0081 | 0.9880 | |
| TCGA | NUPR1 | 26471 | RNAseq | -0.0289 | 0.7746 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUPR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUPR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUPR1 | 26471 | 4 | 5 | 21 | |
| GSE20123 | NUPR1 | 26471 | 4 | 4 | 22 | |
| GSE43470 | NUPR1 | 26471 | 4 | 3 | 36 | |
| GSE46452 | NUPR1 | 26471 | 38 | 1 | 20 | |
| GSE47630 | NUPR1 | 26471 | 11 | 7 | 22 | |
| GSE54993 | NUPR1 | 26471 | 3 | 5 | 62 | |
| GSE54994 | NUPR1 | 26471 | 4 | 9 | 40 | |
| GSE60625 | NUPR1 | 26471 | 4 | 0 | 7 | |
| GSE74703 | NUPR1 | 26471 | 4 | 2 | 30 | |
| GSE74704 | NUPR1 | 26471 | 3 | 2 | 15 | |
| TCGA | NUPR1 | 26471 | 20 | 12 | 64 |
Total number of gains: 99; Total number of losses: 50; Total Number of normals: 339.
Somatic mutations of NUPR1:
Generating mutation plots.
Highly correlated genes for NUPR1:
Showing top 20/266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUPR1 | EIF3K | 0.766965 | 3 | 0 | 3 |
| NUPR1 | TSPYL2 | 0.758807 | 3 | 0 | 3 |
| NUPR1 | NDUFA8 | 0.737688 | 3 | 0 | 3 |
| NUPR1 | LETMD1 | 0.736582 | 3 | 0 | 3 |
| NUPR1 | GPD1L | 0.72413 | 3 | 0 | 3 |
| NUPR1 | APOO | 0.713186 | 3 | 0 | 3 |
| NUPR1 | C1orf35 | 0.710618 | 3 | 0 | 3 |
| NUPR1 | NCOR2 | 0.710573 | 3 | 0 | 3 |
| NUPR1 | FBXO8 | 0.704837 | 3 | 0 | 3 |
| NUPR1 | AKAP17A | 0.703085 | 3 | 0 | 3 |
| NUPR1 | VPS11 | 0.701763 | 4 | 0 | 4 |
| NUPR1 | SUCLG2 | 0.693606 | 3 | 0 | 3 |
| NUPR1 | RWDD4 | 0.687113 | 3 | 0 | 3 |
| NUPR1 | EVL | 0.686669 | 3 | 0 | 3 |
| NUPR1 | BCLAF1 | 0.68359 | 3 | 0 | 3 |
| NUPR1 | KIAA1328 | 0.682357 | 3 | 0 | 3 |
| NUPR1 | NXF1 | 0.681835 | 3 | 0 | 3 |
| NUPR1 | MICA | 0.680691 | 3 | 0 | 3 |
| NUPR1 | RPL41 | 0.6783 | 4 | 0 | 4 |
| NUPR1 | CYP4V2 | 0.676969 | 3 | 0 | 3 |
For details and further investigation, click here
