| Full name: neurexophilin 4 | Alias Symbol: NPH4 | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 11247 | HGNC ID: HGNC:8078 | Ensembl Gene: ENSG00000182379 | OMIM ID: 604637 |
| Drug and gene relationship at DGIdb | |||
Expression of NXPH4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NXPH4 | 11247 | 221967_at | 0.5907 | 0.0306 | |
| GSE20347 | NXPH4 | 11247 | 221967_at | 0.5240 | 0.0000 | |
| GSE23400 | NXPH4 | 11247 | 221967_at | 0.0608 | 0.2674 | |
| GSE26886 | NXPH4 | 11247 | 221967_at | 0.2656 | 0.0516 | |
| GSE29001 | NXPH4 | 11247 | 221967_at | 0.1840 | 0.4798 | |
| GSE38129 | NXPH4 | 11247 | 221967_at | 0.5179 | 0.0000 | |
| GSE45670 | NXPH4 | 11247 | 221967_at | 0.2326 | 0.0657 | |
| GSE53622 | NXPH4 | 11247 | 115455 | 1.9283 | 0.0000 | |
| GSE53624 | NXPH4 | 11247 | 115455 | 1.8651 | 0.0000 | |
| GSE63941 | NXPH4 | 11247 | 221967_at | 0.8173 | 0.0134 | |
| GSE77861 | NXPH4 | 11247 | 221967_at | 0.3663 | 0.1558 | |
| GSE97050 | NXPH4 | 11247 | A_33_P3363245 | 0.9920 | 0.1734 | |
| SRP007169 | NXPH4 | 11247 | RNAseq | 2.6031 | 0.0007 | |
| SRP133303 | NXPH4 | 11247 | RNAseq | 3.5086 | 0.0000 | |
| SRP159526 | NXPH4 | 11247 | RNAseq | 3.3526 | 0.0000 | |
| SRP219564 | NXPH4 | 11247 | RNAseq | 2.6602 | 0.0004 | |
| TCGA | NXPH4 | 11247 | RNAseq | 2.1064 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by NXPH4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NXPH4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NXPH4 | 11247 | 7 | 1 | 22 | |
| GSE20123 | NXPH4 | 11247 | 7 | 0 | 23 | |
| GSE43470 | NXPH4 | 11247 | 3 | 0 | 40 | |
| GSE46452 | NXPH4 | 11247 | 8 | 1 | 50 | |
| GSE47630 | NXPH4 | 11247 | 10 | 2 | 28 | |
| GSE54993 | NXPH4 | 11247 | 0 | 5 | 65 | |
| GSE54994 | NXPH4 | 11247 | 4 | 1 | 48 | |
| GSE60625 | NXPH4 | 11247 | 0 | 0 | 11 | |
| GSE74703 | NXPH4 | 11247 | 3 | 0 | 33 | |
| GSE74704 | NXPH4 | 11247 | 4 | 0 | 16 | |
| TCGA | NXPH4 | 11247 | 14 | 10 | 72 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of NXPH4:
Generating mutation plots.
Highly correlated genes for NXPH4:
Showing top 20/910 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NXPH4 | ADAP1 | 0.712999 | 4 | 0 | 4 |
| NXPH4 | CEMP1 | 0.70658 | 3 | 0 | 3 |
| NXPH4 | EPN1 | 0.706161 | 5 | 0 | 5 |
| NXPH4 | CCT5 | 0.686799 | 4 | 0 | 4 |
| NXPH4 | SAMD1 | 0.685465 | 6 | 0 | 6 |
| NXPH4 | UBAP2L | 0.677716 | 5 | 0 | 4 |
| NXPH4 | CABP4 | 0.671595 | 3 | 0 | 3 |
| NXPH4 | IGLL1 | 0.663884 | 4 | 0 | 3 |
| NXPH4 | GPRIN1 | 0.661568 | 6 | 0 | 6 |
| NXPH4 | INSL5 | 0.656756 | 3 | 0 | 3 |
| NXPH4 | ECT2 | 0.656511 | 7 | 0 | 6 |
| NXPH4 | APLP1 | 0.65539 | 4 | 0 | 3 |
| NXPH4 | DNAJB11 | 0.655042 | 4 | 0 | 4 |
| NXPH4 | FIBCD1 | 0.652755 | 3 | 0 | 3 |
| NXPH4 | AGRN | 0.652394 | 9 | 0 | 8 |
| NXPH4 | TMEM63B | 0.650453 | 4 | 0 | 3 |
| NXPH4 | LIMK1 | 0.646636 | 8 | 0 | 6 |
| NXPH4 | NOP2 | 0.646605 | 6 | 0 | 6 |
| NXPH4 | MTERF3 | 0.645484 | 4 | 0 | 3 |
| NXPH4 | BOP1 | 0.644848 | 3 | 0 | 3 |
For details and further investigation, click here
