| Full name: NYN domain and retroviral integrase containing | Alias Symbol: FLJ11811|CGIN1 | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 57523 | HGNC ID: HGNC:20165 | Ensembl Gene: ENSG00000205978 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NYNRIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NYNRIN | 57523 | 220911_s_at | -0.1469 | 0.8675 | |
| GSE20347 | NYNRIN | 57523 | 220911_s_at | -0.7888 | 0.0002 | |
| GSE23400 | NYNRIN | 57523 | 220911_s_at | -0.5593 | 0.0000 | |
| GSE26886 | NYNRIN | 57523 | 220911_s_at | -0.7587 | 0.0264 | |
| GSE29001 | NYNRIN | 57523 | 220911_s_at | -0.8125 | 0.0384 | |
| GSE38129 | NYNRIN | 57523 | 220911_s_at | -0.8468 | 0.0000 | |
| GSE45670 | NYNRIN | 57523 | 220911_s_at | -0.4807 | 0.0067 | |
| GSE53622 | NYNRIN | 57523 | 7179 | -1.0104 | 0.0000 | |
| GSE53624 | NYNRIN | 57523 | 7179 | -1.0459 | 0.0000 | |
| GSE63941 | NYNRIN | 57523 | 220911_s_at | 0.0136 | 0.9885 | |
| GSE77861 | NYNRIN | 57523 | 220911_s_at | -0.6566 | 0.1575 | |
| GSE97050 | NYNRIN | 57523 | A_23_P129005 | -0.5660 | 0.2041 | |
| SRP007169 | NYNRIN | 57523 | RNAseq | -1.9341 | 0.0002 | |
| SRP008496 | NYNRIN | 57523 | RNAseq | -1.7492 | 0.0001 | |
| SRP064894 | NYNRIN | 57523 | RNAseq | -0.8299 | 0.0066 | |
| SRP133303 | NYNRIN | 57523 | RNAseq | -1.5694 | 0.0000 | |
| SRP159526 | NYNRIN | 57523 | RNAseq | -1.5858 | 0.0000 | |
| SRP193095 | NYNRIN | 57523 | RNAseq | -1.1432 | 0.0000 | |
| SRP219564 | NYNRIN | 57523 | RNAseq | -0.8107 | 0.1523 | |
| TCGA | NYNRIN | 57523 | RNAseq | -0.3572 | 0.0108 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by NYNRIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NYNRIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NYNRIN | 57523 | 8 | 3 | 19 | |
| GSE20123 | NYNRIN | 57523 | 8 | 3 | 19 | |
| GSE43470 | NYNRIN | 57523 | 8 | 2 | 33 | |
| GSE46452 | NYNRIN | 57523 | 16 | 2 | 41 | |
| GSE47630 | NYNRIN | 57523 | 11 | 10 | 19 | |
| GSE54993 | NYNRIN | 57523 | 3 | 11 | 56 | |
| GSE54994 | NYNRIN | 57523 | 18 | 5 | 30 | |
| GSE60625 | NYNRIN | 57523 | 0 | 2 | 9 | |
| GSE74703 | NYNRIN | 57523 | 7 | 2 | 27 | |
| GSE74704 | NYNRIN | 57523 | 3 | 2 | 15 | |
| TCGA | NYNRIN | 57523 | 27 | 12 | 57 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of NYNRIN:
Generating mutation plots.
Highly correlated genes for NYNRIN:
Showing top 20/377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NYNRIN | NRG4 | 0.69342 | 3 | 0 | 3 |
| NYNRIN | AVPR2 | 0.686246 | 4 | 0 | 4 |
| NYNRIN | NICN1 | 0.676494 | 3 | 0 | 3 |
| NYNRIN | SHROOM4 | 0.675685 | 3 | 0 | 3 |
| NYNRIN | OR10G8 | 0.673202 | 3 | 0 | 3 |
| NYNRIN | FAM163B | 0.668227 | 3 | 0 | 3 |
| NYNRIN | NDRG2 | 0.659845 | 10 | 0 | 8 |
| NYNRIN | CTTNBP2 | 0.657677 | 6 | 0 | 6 |
| NYNRIN | FAM189A2 | 0.655928 | 10 | 0 | 10 |
| NYNRIN | ANKRD35 | 0.655682 | 4 | 0 | 4 |
| NYNRIN | TEN1 | 0.654953 | 3 | 0 | 3 |
| NYNRIN | NCR1 | 0.647615 | 3 | 0 | 3 |
| NYNRIN | OXER1 | 0.645666 | 3 | 0 | 3 |
| NYNRIN | LGALS3 | 0.642135 | 8 | 0 | 8 |
| NYNRIN | PDZD2 | 0.641289 | 11 | 0 | 8 |
| NYNRIN | OTOF | 0.639672 | 4 | 0 | 3 |
| NYNRIN | TNR | 0.633955 | 4 | 0 | 3 |
| NYNRIN | HES5 | 0.629034 | 3 | 0 | 3 |
| NYNRIN | NCALD | 0.625028 | 3 | 0 | 3 |
| NYNRIN | NANOS2 | 0.623857 | 4 | 0 | 3 |
For details and further investigation, click here
