| Full name: O-linked N-acetylglucosamine (GlcNAc) transferase | Alias Symbol: O-GLCNAC|HRNT1|MGC22921|FLJ23071|OGT1 | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 8473 | HGNC ID: HGNC:8127 | Ensembl Gene: ENSG00000147162 | OMIM ID: 300255 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
OGT involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04931 | Insulin resistance |
Expression of OGT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OGT | 8473 | 209240_at | -0.1643 | 0.8221 | |
| GSE20347 | OGT | 8473 | 209240_at | 0.1191 | 0.3329 | |
| GSE23400 | OGT | 8473 | 209240_at | 0.2147 | 0.0150 | |
| GSE26886 | OGT | 8473 | 209240_at | 0.3918 | 0.1188 | |
| GSE29001 | OGT | 8473 | 209240_at | 0.0118 | 0.9629 | |
| GSE38129 | OGT | 8473 | 209240_at | 0.0506 | 0.7932 | |
| GSE45670 | OGT | 8473 | 209240_at | -0.4283 | 0.0198 | |
| GSE53622 | OGT | 8473 | 29355 | 0.1436 | 0.0492 | |
| GSE53624 | OGT | 8473 | 38710 | -0.0466 | 0.5111 | |
| GSE63941 | OGT | 8473 | 209240_at | -0.0829 | 0.8976 | |
| GSE77861 | OGT | 8473 | 209240_at | 0.2230 | 0.3282 | |
| GSE97050 | OGT | 8473 | A_33_P3227284 | -0.0730 | 0.7683 | |
| SRP007169 | OGT | 8473 | RNAseq | -0.0226 | 0.9484 | |
| SRP008496 | OGT | 8473 | RNAseq | 0.0909 | 0.6016 | |
| SRP064894 | OGT | 8473 | RNAseq | 0.0227 | 0.9207 | |
| SRP133303 | OGT | 8473 | RNAseq | -0.1592 | 0.1894 | |
| SRP159526 | OGT | 8473 | RNAseq | -0.5470 | 0.0236 | |
| SRP193095 | OGT | 8473 | RNAseq | -0.0618 | 0.6157 | |
| SRP219564 | OGT | 8473 | RNAseq | -0.0460 | 0.9187 | |
| TCGA | OGT | 8473 | RNAseq | -0.0942 | 0.0869 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OGT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OGT:
No record found for this gene.
Somatic mutations of OGT:
Generating mutation plots.
Highly correlated genes for OGT:
Showing top 20/291 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OGT | OSGEPL1 | 0.785112 | 3 | 0 | 3 |
| OGT | EIF2D | 0.76007 | 3 | 0 | 3 |
| OGT | ZC3HAV1 | 0.721768 | 3 | 0 | 3 |
| OGT | SMCR8 | 0.720346 | 3 | 0 | 3 |
| OGT | STRBP | 0.715642 | 3 | 0 | 3 |
| OGT | ZNF184 | 0.710638 | 3 | 0 | 3 |
| OGT | ZBTB41 | 0.705847 | 4 | 0 | 3 |
| OGT | CASP8AP2 | 0.703708 | 4 | 0 | 4 |
| OGT | RNF139 | 0.70362 | 3 | 0 | 3 |
| OGT | TMED8 | 0.701359 | 3 | 0 | 3 |
| OGT | RNF113A | 0.701337 | 3 | 0 | 3 |
| OGT | GIMAP7 | 0.699639 | 3 | 0 | 3 |
| OGT | RCBTB2 | 0.691999 | 3 | 0 | 3 |
| OGT | ZNF518B | 0.687782 | 4 | 0 | 3 |
| OGT | SH2B2 | 0.686942 | 3 | 0 | 3 |
| OGT | DPY19L3 | 0.684885 | 3 | 0 | 3 |
| OGT | TAF9B | 0.680265 | 3 | 0 | 3 |
| OGT | METTL5 | 0.677485 | 3 | 0 | 3 |
| OGT | IL6R | 0.677033 | 3 | 0 | 3 |
| OGT | TCF20 | 0.676048 | 3 | 0 | 3 |
For details and further investigation, click here
