| Full name: RCC1 and BTB domain containing protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q14.2 | ||
| Entrez ID: 1102 | HGNC ID: HGNC:1914 | Ensembl Gene: ENSG00000136161 | OMIM ID: 603524 |
| Drug and gene relationship at DGIdb | |||
Expression of RCBTB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCBTB2 | 1102 | 204759_at | -0.6893 | 0.2478 | |
| GSE20347 | RCBTB2 | 1102 | 204759_at | -0.8017 | 0.0022 | |
| GSE23400 | RCBTB2 | 1102 | 204759_at | -0.2681 | 0.0017 | |
| GSE26886 | RCBTB2 | 1102 | 204759_at | -1.3091 | 0.0001 | |
| GSE29001 | RCBTB2 | 1102 | 204759_at | -0.5184 | 0.0052 | |
| GSE38129 | RCBTB2 | 1102 | 204759_at | -0.6843 | 0.0002 | |
| GSE45670 | RCBTB2 | 1102 | 204759_at | -0.2819 | 0.1648 | |
| GSE53622 | RCBTB2 | 1102 | 49547 | -0.6214 | 0.0000 | |
| GSE53624 | RCBTB2 | 1102 | 49547 | -0.7979 | 0.0000 | |
| GSE63941 | RCBTB2 | 1102 | 204759_at | -1.9403 | 0.0059 | |
| GSE77861 | RCBTB2 | 1102 | 204759_at | -0.5496 | 0.2225 | |
| GSE97050 | RCBTB2 | 1102 | A_23_P14105 | -0.5495 | 0.1012 | |
| SRP007169 | RCBTB2 | 1102 | RNAseq | -1.3043 | 0.0003 | |
| SRP008496 | RCBTB2 | 1102 | RNAseq | -1.0363 | 0.0000 | |
| SRP064894 | RCBTB2 | 1102 | RNAseq | -0.4035 | 0.0462 | |
| SRP133303 | RCBTB2 | 1102 | RNAseq | -0.6644 | 0.0001 | |
| SRP159526 | RCBTB2 | 1102 | RNAseq | -1.3148 | 0.0008 | |
| SRP193095 | RCBTB2 | 1102 | RNAseq | -0.5071 | 0.0015 | |
| SRP219564 | RCBTB2 | 1102 | RNAseq | -0.5562 | 0.0642 | |
| TCGA | RCBTB2 | 1102 | RNAseq | -0.0844 | 0.3357 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by RCBTB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCBTB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCBTB2 | 1102 | 1 | 13 | 16 | |
| GSE20123 | RCBTB2 | 1102 | 1 | 12 | 17 | |
| GSE43470 | RCBTB2 | 1102 | 3 | 13 | 27 | |
| GSE46452 | RCBTB2 | 1102 | 0 | 32 | 27 | |
| GSE47630 | RCBTB2 | 1102 | 2 | 27 | 11 | |
| GSE54993 | RCBTB2 | 1102 | 12 | 2 | 56 | |
| GSE54994 | RCBTB2 | 1102 | 1 | 17 | 35 | |
| GSE60625 | RCBTB2 | 1102 | 0 | 3 | 8 | |
| GSE74703 | RCBTB2 | 1102 | 3 | 10 | 23 | |
| GSE74704 | RCBTB2 | 1102 | 0 | 9 | 11 | |
| TCGA | RCBTB2 | 1102 | 7 | 38 | 51 |
Total number of gains: 30; Total number of losses: 176; Total Number of normals: 282.
Somatic mutations of RCBTB2:
Generating mutation plots.
Highly correlated genes for RCBTB2:
Showing top 20/950 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCBTB2 | RPS27L | 0.752869 | 3 | 0 | 3 |
| RCBTB2 | PREX2 | 0.714605 | 3 | 0 | 3 |
| RCBTB2 | GPCPD1 | 0.705445 | 3 | 0 | 3 |
| RCBTB2 | FBXO8 | 0.703865 | 5 | 0 | 5 |
| RCBTB2 | USP9Y | 0.703065 | 3 | 0 | 3 |
| RCBTB2 | SYTL4 | 0.702745 | 4 | 0 | 4 |
| RCBTB2 | CWC22 | 0.69972 | 3 | 0 | 3 |
| RCBTB2 | EAF1 | 0.695944 | 3 | 0 | 3 |
| RCBTB2 | OGT | 0.691999 | 3 | 0 | 3 |
| RCBTB2 | CLEC3B | 0.691614 | 3 | 0 | 3 |
| RCBTB2 | GIMAP5 | 0.687662 | 3 | 0 | 3 |
| RCBTB2 | GUF1 | 0.683766 | 4 | 0 | 3 |
| RCBTB2 | BDP1 | 0.683021 | 4 | 0 | 3 |
| RCBTB2 | PIGP | 0.677756 | 4 | 0 | 3 |
| RCBTB2 | NR2F1 | 0.676232 | 3 | 0 | 3 |
| RCBTB2 | POLI | 0.671954 | 4 | 0 | 3 |
| RCBTB2 | WDFY3 | 0.671828 | 5 | 0 | 5 |
| RCBTB2 | MTIF3 | 0.671753 | 7 | 0 | 7 |
| RCBTB2 | CCDC12 | 0.671648 | 3 | 0 | 3 |
| RCBTB2 | FAR1 | 0.669762 | 3 | 0 | 3 |
For details and further investigation, click here
