| Full name: spermatid perinuclear RNA binding protein | Alias Symbol: FLJ11307|SPNR | ||
| Type: protein-coding gene | Cytoband: 9q33.1-q33.3 | ||
| Entrez ID: 55342 | HGNC ID: HGNC:16462 | Ensembl Gene: ENSG00000165209 | OMIM ID: 611138 |
| Drug and gene relationship at DGIdb | |||
Expression of STRBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRBP | 55342 | 233252_s_at | -0.5339 | 0.2080 | |
| GSE26886 | STRBP | 55342 | 223245_at | 0.2743 | 0.2933 | |
| GSE45670 | STRBP | 55342 | 233252_s_at | -0.3051 | 0.2317 | |
| GSE53622 | STRBP | 55342 | 40512 | -0.4691 | 0.0000 | |
| GSE53624 | STRBP | 55342 | 40512 | -0.4411 | 0.0000 | |
| GSE63941 | STRBP | 55342 | 223245_at | 1.8727 | 0.0054 | |
| GSE77861 | STRBP | 55342 | 223245_at | -0.0091 | 0.9735 | |
| GSE97050 | STRBP | 55342 | A_23_P252155 | -0.2552 | 0.4303 | |
| SRP007169 | STRBP | 55342 | RNAseq | 0.5934 | 0.1624 | |
| SRP008496 | STRBP | 55342 | RNAseq | 1.1127 | 0.0033 | |
| SRP064894 | STRBP | 55342 | RNAseq | -0.9104 | 0.0007 | |
| SRP133303 | STRBP | 55342 | RNAseq | -0.7047 | 0.0003 | |
| SRP159526 | STRBP | 55342 | RNAseq | -0.1289 | 0.6727 | |
| SRP193095 | STRBP | 55342 | RNAseq | -0.7964 | 0.0000 | |
| SRP219564 | STRBP | 55342 | RNAseq | -0.7595 | 0.1027 | |
| TCGA | STRBP | 55342 | RNAseq | 0.0552 | 0.5020 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by STRBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRBP | 55342 | 3 | 8 | 19 | |
| GSE20123 | STRBP | 55342 | 3 | 8 | 19 | |
| GSE43470 | STRBP | 55342 | 5 | 4 | 34 | |
| GSE46452 | STRBP | 55342 | 6 | 13 | 40 | |
| GSE47630 | STRBP | 55342 | 3 | 16 | 21 | |
| GSE54993 | STRBP | 55342 | 3 | 3 | 64 | |
| GSE54994 | STRBP | 55342 | 9 | 10 | 34 | |
| GSE60625 | STRBP | 55342 | 0 | 0 | 11 | |
| GSE74703 | STRBP | 55342 | 5 | 3 | 28 | |
| GSE74704 | STRBP | 55342 | 2 | 6 | 12 | |
| TCGA | STRBP | 55342 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 95; Total Number of normals: 327.
Somatic mutations of STRBP:
Generating mutation plots.
Highly correlated genes for STRBP:
Showing top 20/295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRBP | OPHN1 | 0.846405 | 3 | 0 | 3 |
| STRBP | ZNF280C | 0.779586 | 3 | 0 | 3 |
| STRBP | FBL | 0.755163 | 3 | 0 | 3 |
| STRBP | MTPAP | 0.724325 | 3 | 0 | 3 |
| STRBP | EDF1 | 0.716599 | 3 | 0 | 3 |
| STRBP | MRPL13 | 0.716277 | 3 | 0 | 3 |
| STRBP | OGT | 0.715642 | 3 | 0 | 3 |
| STRBP | FBXO11 | 0.710328 | 3 | 0 | 3 |
| STRBP | CHD7 | 0.708327 | 3 | 0 | 3 |
| STRBP | UEVLD | 0.70798 | 3 | 0 | 3 |
| STRBP | RPRD2 | 0.705978 | 3 | 0 | 3 |
| STRBP | MFN1 | 0.701845 | 3 | 0 | 3 |
| STRBP | CYP2C19 | 0.701298 | 3 | 0 | 3 |
| STRBP | RAB5A | 0.694538 | 3 | 0 | 3 |
| STRBP | MAU2 | 0.691717 | 4 | 0 | 4 |
| STRBP | TBL1Y | 0.691455 | 3 | 0 | 3 |
| STRBP | KDM5A | 0.689606 | 3 | 0 | 3 |
| STRBP | FOPNL | 0.688901 | 3 | 0 | 3 |
| STRBP | TRAPPC1 | 0.686499 | 3 | 0 | 3 |
| STRBP | EIF3M | 0.686266 | 3 | 0 | 3 |
For details and further investigation, click here
