| Full name: methyltransferase like 5 | Alias Symbol: HSPC133 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 29081 | HGNC ID: HGNC:25006 | Ensembl Gene: ENSG00000138382 | OMIM ID: |
Screen Evidence:
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Expression of METTL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL5 | 29081 | 221570_s_at | 0.4094 | 0.5117 | |
| GSE20347 | METTL5 | 29081 | 221570_s_at | 0.7694 | 0.0000 | |
| GSE23400 | METTL5 | 29081 | 221570_s_at | 0.7819 | 0.0000 | |
| GSE26886 | METTL5 | 29081 | 221570_s_at | 1.2094 | 0.0000 | |
| GSE29001 | METTL5 | 29081 | 221570_s_at | 0.8961 | 0.0243 | |
| GSE38129 | METTL5 | 29081 | 221570_s_at | 0.5864 | 0.0000 | |
| GSE45670 | METTL5 | 29081 | 221570_s_at | 0.2148 | 0.2014 | |
| GSE53622 | METTL5 | 29081 | 27044 | 0.4706 | 0.0000 | |
| GSE53624 | METTL5 | 29081 | 27044 | 0.7936 | 0.0000 | |
| GSE63941 | METTL5 | 29081 | 221570_s_at | 0.9166 | 0.0121 | |
| GSE77861 | METTL5 | 29081 | 221570_s_at | 0.6718 | 0.0102 | |
| GSE97050 | METTL5 | 29081 | A_33_P3272461 | -0.0222 | 0.9474 | |
| SRP007169 | METTL5 | 29081 | RNAseq | 0.3856 | 0.3778 | |
| SRP008496 | METTL5 | 29081 | RNAseq | 0.6376 | 0.0090 | |
| SRP064894 | METTL5 | 29081 | RNAseq | 0.3809 | 0.0651 | |
| SRP133303 | METTL5 | 29081 | RNAseq | 0.5585 | 0.0002 | |
| SRP159526 | METTL5 | 29081 | RNAseq | 0.1080 | 0.6646 | |
| SRP193095 | METTL5 | 29081 | RNAseq | 0.1428 | 0.3543 | |
| SRP219564 | METTL5 | 29081 | RNAseq | -0.0178 | 0.9616 | |
| TCGA | METTL5 | 29081 | RNAseq | 0.1109 | 0.0470 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by METTL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL5 | 29081 | 8 | 0 | 22 | |
| GSE20123 | METTL5 | 29081 | 8 | 0 | 22 | |
| GSE43470 | METTL5 | 29081 | 4 | 1 | 38 | |
| GSE46452 | METTL5 | 29081 | 1 | 4 | 54 | |
| GSE47630 | METTL5 | 29081 | 5 | 3 | 32 | |
| GSE54993 | METTL5 | 29081 | 0 | 5 | 65 | |
| GSE54994 | METTL5 | 29081 | 11 | 3 | 39 | |
| GSE60625 | METTL5 | 29081 | 0 | 3 | 8 | |
| GSE74703 | METTL5 | 29081 | 3 | 1 | 32 | |
| GSE74704 | METTL5 | 29081 | 4 | 0 | 16 | |
| TCGA | METTL5 | 29081 | 24 | 10 | 62 |
Total number of gains: 68; Total number of losses: 30; Total Number of normals: 390.
Somatic mutations of METTL5:
Generating mutation plots.
Highly correlated genes for METTL5:
Showing top 20/1513 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL5 | ANAPC4 | 0.843369 | 3 | 0 | 3 |
| METTL5 | SMCR8 | 0.831193 | 3 | 0 | 3 |
| METTL5 | SSB | 0.805837 | 13 | 0 | 12 |
| METTL5 | TMTC1 | 0.78767 | 3 | 0 | 3 |
| METTL5 | PPP1R16A | 0.780584 | 3 | 0 | 3 |
| METTL5 | METTL14 | 0.764022 | 3 | 0 | 3 |
| METTL5 | RBM4 | 0.755584 | 3 | 0 | 3 |
| METTL5 | NDUFS4 | 0.752527 | 3 | 0 | 3 |
| METTL5 | ASNSD1 | 0.744372 | 10 | 0 | 9 |
| METTL5 | MRFAP1 | 0.742077 | 3 | 0 | 3 |
| METTL5 | MAGOH | 0.737386 | 3 | 0 | 3 |
| METTL5 | ZNF766 | 0.737371 | 3 | 0 | 3 |
| METTL5 | DUS3L | 0.733183 | 4 | 0 | 4 |
| METTL5 | STK3 | 0.730061 | 11 | 0 | 11 |
| METTL5 | UBXN2A | 0.724056 | 3 | 0 | 3 |
| METTL5 | PSMD14 | 0.720607 | 12 | 0 | 12 |
| METTL5 | SFSWAP | 0.719997 | 3 | 0 | 3 |
| METTL5 | KLHL5 | 0.715477 | 4 | 0 | 4 |
| METTL5 | NRARP | 0.7142 | 3 | 0 | 3 |
| METTL5 | DHX36 | 0.712995 | 8 | 0 | 8 |
For details and further investigation, click here
