| Full name: poly(ADP-ribose) polymerase family member 9 | Alias Symbol: BAL|BAL1 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 83666 | HGNC ID: HGNC:24118 | Ensembl Gene: ENSG00000138496 | OMIM ID: 612065 |
| Drug and gene relationship at DGIdb | |||
Expression of PARP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PARP9 | 83666 | 223220_s_at | 0.2634 | 0.7041 | |
| GSE26886 | PARP9 | 83666 | 223220_s_at | 0.1427 | 0.6960 | |
| GSE45670 | PARP9 | 83666 | 223220_s_at | 1.5432 | 0.0000 | |
| GSE53622 | PARP9 | 83666 | 64555 | 0.6959 | 0.0000 | |
| GSE53624 | PARP9 | 83666 | 64555 | 0.6746 | 0.0000 | |
| GSE63941 | PARP9 | 83666 | 223220_s_at | -0.4127 | 0.6931 | |
| GSE77861 | PARP9 | 83666 | 223220_s_at | -0.0747 | 0.9151 | |
| GSE97050 | PARP9 | 83666 | A_23_P69383 | 0.6032 | 0.2004 | |
| SRP007169 | PARP9 | 83666 | RNAseq | 1.1384 | 0.0220 | |
| SRP008496 | PARP9 | 83666 | RNAseq | 0.6557 | 0.1172 | |
| SRP064894 | PARP9 | 83666 | RNAseq | 1.5511 | 0.0000 | |
| SRP133303 | PARP9 | 83666 | RNAseq | 0.9176 | 0.0015 | |
| SRP159526 | PARP9 | 83666 | RNAseq | -0.3801 | 0.5238 | |
| SRP193095 | PARP9 | 83666 | RNAseq | 0.9266 | 0.0000 | |
| SRP219564 | PARP9 | 83666 | RNAseq | 0.2992 | 0.5954 | |
| TCGA | PARP9 | 83666 | RNAseq | 0.3294 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PARP9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PARP9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PARP9 | 83666 | 18 | 0 | 12 | |
| GSE20123 | PARP9 | 83666 | 18 | 0 | 12 | |
| GSE43470 | PARP9 | 83666 | 20 | 0 | 23 | |
| GSE46452 | PARP9 | 83666 | 14 | 5 | 40 | |
| GSE47630 | PARP9 | 83666 | 17 | 4 | 19 | |
| GSE54993 | PARP9 | 83666 | 2 | 6 | 62 | |
| GSE54994 | PARP9 | 83666 | 30 | 4 | 19 | |
| GSE60625 | PARP9 | 83666 | 0 | 6 | 5 | |
| GSE74703 | PARP9 | 83666 | 16 | 0 | 20 | |
| GSE74704 | PARP9 | 83666 | 13 | 0 | 7 | |
| TCGA | PARP9 | 83666 | 54 | 6 | 36 |
Total number of gains: 202; Total number of losses: 31; Total Number of normals: 255.
Somatic mutations of PARP9:
Generating mutation plots.
Highly correlated genes for PARP9:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PARP9 | DTX3L | 0.815236 | 9 | 0 | 9 |
| PARP9 | MX1 | 0.767196 | 8 | 0 | 8 |
| PARP9 | PARP14 | 0.765216 | 9 | 0 | 9 |
| PARP9 | IFIH1 | 0.764654 | 7 | 0 | 7 |
| PARP9 | OAS2 | 0.747394 | 8 | 0 | 8 |
| PARP9 | EPSTI1 | 0.745647 | 7 | 0 | 6 |
| PARP9 | RTP4 | 0.743295 | 9 | 0 | 9 |
| PARP9 | PLSCR1 | 0.741436 | 8 | 0 | 8 |
| PARP9 | NMI | 0.734254 | 9 | 0 | 8 |
| PARP9 | STAT1 | 0.726589 | 8 | 0 | 8 |
| PARP9 | SP110 | 0.726235 | 8 | 0 | 7 |
| PARP9 | LAMP3 | 0.723568 | 7 | 0 | 7 |
| PARP9 | OSBPL7 | 0.720126 | 3 | 0 | 3 |
| PARP9 | STAT2 | 0.718001 | 5 | 0 | 4 |
| PARP9 | GBP1 | 0.716635 | 8 | 0 | 8 |
| PARP9 | FBXO6 | 0.715172 | 7 | 0 | 7 |
| PARP9 | IFIT1 | 0.714391 | 9 | 0 | 9 |
| PARP9 | DDX60 | 0.708102 | 9 | 0 | 8 |
| PARP9 | IFI44L | 0.707373 | 8 | 0 | 8 |
| PARP9 | IFI44 | 0.705086 | 9 | 0 | 8 |
For details and further investigation, click here
