| Full name: O-sialoglycoprotein endopeptidase | Alias Symbol: PRSMG1|GCPL1|OSGEP1|KAE1|TCS3 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 55644 | HGNC ID: HGNC:18028 | Ensembl Gene: ENSG00000092094 | OMIM ID: 610107 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of OSGEP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSGEP | 55644 | 209450_at | 0.2744 | 0.6496 | |
| GSE20347 | OSGEP | 55644 | 209450_at | 0.2524 | 0.1557 | |
| GSE23400 | OSGEP | 55644 | 209450_at | 0.0536 | 0.3684 | |
| GSE26886 | OSGEP | 55644 | 209450_at | 0.0463 | 0.8425 | |
| GSE29001 | OSGEP | 55644 | 209450_at | 0.1180 | 0.6940 | |
| GSE38129 | OSGEP | 55644 | 209450_at | 0.2390 | 0.0473 | |
| GSE45670 | OSGEP | 55644 | 209450_at | 0.0169 | 0.9338 | |
| GSE53622 | OSGEP | 55644 | 60676 | 0.2637 | 0.0017 | |
| GSE53624 | OSGEP | 55644 | 60676 | 0.3082 | 0.0000 | |
| GSE63941 | OSGEP | 55644 | 209450_at | 0.0650 | 0.9175 | |
| GSE77861 | OSGEP | 55644 | 209450_at | 0.2423 | 0.4972 | |
| GSE97050 | OSGEP | 55644 | A_23_P54079 | 0.2552 | 0.3181 | |
| SRP007169 | OSGEP | 55644 | RNAseq | 0.1576 | 0.7373 | |
| SRP008496 | OSGEP | 55644 | RNAseq | 0.0589 | 0.8509 | |
| SRP064894 | OSGEP | 55644 | RNAseq | 0.4542 | 0.0036 | |
| SRP133303 | OSGEP | 55644 | RNAseq | -0.0944 | 0.5926 | |
| SRP159526 | OSGEP | 55644 | RNAseq | 0.2819 | 0.3392 | |
| SRP193095 | OSGEP | 55644 | RNAseq | 0.0056 | 0.9543 | |
| SRP219564 | OSGEP | 55644 | RNAseq | 0.4159 | 0.2754 | |
| TCGA | OSGEP | 55644 | RNAseq | 0.0253 | 0.7114 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OSGEP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSGEP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSGEP | 55644 | 10 | 3 | 17 | |
| GSE20123 | OSGEP | 55644 | 8 | 3 | 19 | |
| GSE43470 | OSGEP | 55644 | 7 | 1 | 35 | |
| GSE46452 | OSGEP | 55644 | 19 | 2 | 38 | |
| GSE47630 | OSGEP | 55644 | 10 | 10 | 20 | |
| GSE54993 | OSGEP | 55644 | 3 | 11 | 56 | |
| GSE54994 | OSGEP | 55644 | 18 | 5 | 30 | |
| GSE60625 | OSGEP | 55644 | 0 | 2 | 9 | |
| GSE74703 | OSGEP | 55644 | 6 | 1 | 29 | |
| GSE74704 | OSGEP | 55644 | 4 | 2 | 14 | |
| TCGA | OSGEP | 55644 | 28 | 16 | 52 |
Total number of gains: 113; Total number of losses: 56; Total Number of normals: 319.
Somatic mutations of OSGEP:
Generating mutation plots.
Highly correlated genes for OSGEP:
Showing top 20/246 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSGEP | CMTM4 | 0.77526 | 3 | 0 | 3 |
| OSGEP | SS18L1 | 0.773978 | 3 | 0 | 3 |
| OSGEP | PIEZO1 | 0.762631 | 3 | 0 | 3 |
| OSGEP | RAPGEF4 | 0.748712 | 3 | 0 | 3 |
| OSGEP | BRMS1L | 0.745465 | 3 | 0 | 3 |
| OSGEP | TOMM40L | 0.737273 | 3 | 0 | 3 |
| OSGEP | PTP4A2 | 0.735437 | 3 | 0 | 3 |
| OSGEP | TYW5 | 0.734263 | 3 | 0 | 3 |
| OSGEP | RLIM | 0.726884 | 4 | 0 | 4 |
| OSGEP | CNIH3 | 0.72375 | 3 | 0 | 3 |
| OSGEP | QKI | 0.723654 | 3 | 0 | 3 |
| OSGEP | SRA1 | 0.710861 | 3 | 0 | 3 |
| OSGEP | REV1 | 0.70727 | 3 | 0 | 3 |
| OSGEP | FADD | 0.695338 | 4 | 0 | 4 |
| OSGEP | NDUFS2 | 0.693573 | 3 | 0 | 3 |
| OSGEP | PRKX | 0.692926 | 3 | 0 | 3 |
| OSGEP | LRP5L | 0.692684 | 4 | 0 | 3 |
| OSGEP | HEATR5A | 0.692064 | 3 | 0 | 3 |
| OSGEP | PNP | 0.689292 | 4 | 0 | 3 |
| OSGEP | UBLCP1 | 0.689218 | 3 | 0 | 3 |
For details and further investigation, click here
