| Full name: otoraplin | Alias Symbol: MIAL|MIAL1|FDP | ||
| Type: protein-coding gene | Cytoband: 20p12.1 | ||
| Entrez ID: 56914 | HGNC ID: HGNC:8517 | Ensembl Gene: ENSG00000125879 | OMIM ID: 606067 |
| Drug and gene relationship at DGIdb | |||
Expression of OTOR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTOR | 56914 | 221209_s_at | -0.1736 | 0.4464 | |
| GSE20347 | OTOR | 56914 | 221209_s_at | -0.1110 | 0.0973 | |
| GSE23400 | OTOR | 56914 | 221209_s_at | -0.3612 | 0.0000 | |
| GSE26886 | OTOR | 56914 | 221209_s_at | 0.1384 | 0.4298 | |
| GSE29001 | OTOR | 56914 | 221209_s_at | -0.5049 | 0.0049 | |
| GSE38129 | OTOR | 56914 | 221209_s_at | -0.2337 | 0.0037 | |
| GSE45670 | OTOR | 56914 | 221209_s_at | -0.3135 | 0.0042 | |
| GSE53622 | OTOR | 56914 | 37059 | -0.4002 | 0.0032 | |
| GSE53624 | OTOR | 56914 | 43310 | -0.5019 | 0.0009 | |
| GSE63941 | OTOR | 56914 | 221209_s_at | 0.1427 | 0.5311 | |
| GSE77861 | OTOR | 56914 | 221209_s_at | -0.1726 | 0.1820 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OTOR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTOR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTOR | 56914 | 11 | 2 | 17 | |
| GSE20123 | OTOR | 56914 | 11 | 1 | 18 | |
| GSE43470 | OTOR | 56914 | 11 | 1 | 31 | |
| GSE46452 | OTOR | 56914 | 27 | 1 | 31 | |
| GSE47630 | OTOR | 56914 | 17 | 4 | 19 | |
| GSE54993 | OTOR | 56914 | 0 | 15 | 55 | |
| GSE54994 | OTOR | 56914 | 26 | 2 | 25 | |
| GSE60625 | OTOR | 56914 | 0 | 0 | 11 | |
| GSE74703 | OTOR | 56914 | 8 | 1 | 27 | |
| GSE74704 | OTOR | 56914 | 5 | 1 | 14 | |
| TCGA | OTOR | 56914 | 43 | 10 | 43 |
Total number of gains: 159; Total number of losses: 38; Total Number of normals: 291.
Somatic mutations of OTOR:
Generating mutation plots.
Highly correlated genes for OTOR:
Showing top 20/1040 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTOR | CER1 | 0.730133 | 4 | 0 | 4 |
| OTOR | GABRR2 | 0.727236 | 5 | 0 | 5 |
| OTOR | CST8 | 0.720596 | 4 | 0 | 4 |
| OTOR | SLC6A5 | 0.717799 | 3 | 0 | 3 |
| OTOR | CDRT1 | 0.704478 | 3 | 0 | 3 |
| OTOR | PPP3CC | 0.701398 | 3 | 0 | 3 |
| OTOR | CRB1 | 0.700295 | 3 | 0 | 3 |
| OTOR | SSTR4 | 0.697726 | 6 | 0 | 5 |
| OTOR | TSSK2 | 0.69525 | 5 | 0 | 5 |
| OTOR | PSG1 | 0.695062 | 4 | 0 | 4 |
| OTOR | KIR2DS5 | 0.691335 | 4 | 0 | 4 |
| OTOR | PRG3 | 0.689345 | 3 | 0 | 3 |
| OTOR | MAPK8 | 0.688136 | 4 | 0 | 4 |
| OTOR | SLC22A14 | 0.687641 | 4 | 0 | 4 |
| OTOR | RAD52 | 0.68459 | 4 | 0 | 3 |
| OTOR | PSG6 | 0.681129 | 4 | 0 | 4 |
| OTOR | AMACR | 0.680873 | 4 | 0 | 3 |
| OTOR | INO80D | 0.68087 | 5 | 0 | 5 |
| OTOR | INO80C | 0.679039 | 3 | 0 | 3 |
| OTOR | SCN10A | 0.677009 | 3 | 0 | 3 |
For details and further investigation, click here
