| Full name: poly(A) binding protein cytoplasmic 1 like | Alias Symbol: dJ1069P2.3|PABPC1L1|ePAB | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 80336 | HGNC ID: HGNC:15797 | Ensembl Gene: ENSG00000101104 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PABPC1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PABPC1L | 80336 | 226670_s_at | 0.7854 | 0.1724 | |
| GSE26886 | PABPC1L | 80336 | 226670_s_at | 1.2941 | 0.0001 | |
| GSE45670 | PABPC1L | 80336 | 226670_s_at | 0.9493 | 0.0015 | |
| GSE53622 | PABPC1L | 80336 | 43702 | 1.1991 | 0.0000 | |
| GSE53624 | PABPC1L | 80336 | 57659 | 0.8462 | 0.0000 | |
| GSE63941 | PABPC1L | 80336 | 226670_s_at | 0.8303 | 0.2177 | |
| GSE77861 | PABPC1L | 80336 | 226670_s_at | 0.8067 | 0.1364 | |
| GSE97050 | PABPC1L | 80336 | A_33_P3413808 | 0.6661 | 0.1894 | |
| SRP007169 | PABPC1L | 80336 | RNAseq | 1.3713 | 0.0697 | |
| SRP064894 | PABPC1L | 80336 | RNAseq | 1.4169 | 0.0000 | |
| SRP133303 | PABPC1L | 80336 | RNAseq | 0.3646 | 0.0734 | |
| SRP159526 | PABPC1L | 80336 | RNAseq | 1.2362 | 0.0062 | |
| SRP193095 | PABPC1L | 80336 | RNAseq | 0.7827 | 0.0000 | |
| SRP219564 | PABPC1L | 80336 | RNAseq | 1.4141 | 0.0247 | |
| TCGA | PABPC1L | 80336 | RNAseq | 0.3153 | 0.0033 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by PABPC1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PABPC1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PABPC1L | 80336 | 13 | 1 | 16 | |
| GSE20123 | PABPC1L | 80336 | 13 | 1 | 16 | |
| GSE43470 | PABPC1L | 80336 | 12 | 1 | 30 | |
| GSE46452 | PABPC1L | 80336 | 29 | 0 | 30 | |
| GSE47630 | PABPC1L | 80336 | 24 | 1 | 15 | |
| GSE54993 | PABPC1L | 80336 | 0 | 17 | 53 | |
| GSE54994 | PABPC1L | 80336 | 25 | 0 | 28 | |
| GSE60625 | PABPC1L | 80336 | 0 | 0 | 11 | |
| GSE74703 | PABPC1L | 80336 | 10 | 1 | 25 | |
| GSE74704 | PABPC1L | 80336 | 9 | 0 | 11 | |
| TCGA | PABPC1L | 80336 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 25; Total Number of normals: 283.
Somatic mutations of PABPC1L:
Generating mutation plots.
Highly correlated genes for PABPC1L:
Showing top 20/585 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PABPC1L | TNFRSF10A | 0.772392 | 3 | 0 | 3 |
| PABPC1L | KNOP1 | 0.744106 | 3 | 0 | 3 |
| PABPC1L | MTERF3 | 0.725188 | 4 | 0 | 4 |
| PABPC1L | SEMA4F | 0.701715 | 5 | 0 | 5 |
| PABPC1L | TMEM132A | 0.699451 | 4 | 0 | 4 |
| PABPC1L | GOLM1 | 0.697206 | 3 | 0 | 3 |
| PABPC1L | GNLY | 0.696067 | 3 | 0 | 3 |
| PABPC1L | LRFN4 | 0.690905 | 3 | 0 | 3 |
| PABPC1L | KIF18B | 0.683906 | 6 | 0 | 6 |
| PABPC1L | CHRNA5 | 0.680976 | 3 | 0 | 3 |
| PABPC1L | FBXO2 | 0.674439 | 3 | 0 | 3 |
| PABPC1L | C19orf48 | 0.66611 | 3 | 0 | 3 |
| PABPC1L | MS4A18 | 0.665402 | 3 | 0 | 3 |
| PABPC1L | USP49 | 0.663606 | 5 | 0 | 5 |
| PABPC1L | TAS2R30 | 0.663237 | 3 | 0 | 3 |
| PABPC1L | POLG2 | 0.659115 | 7 | 0 | 6 |
| PABPC1L | IRAK1 | 0.657038 | 4 | 0 | 4 |
| PABPC1L | MYO10 | 0.656896 | 5 | 0 | 4 |
| PABPC1L | DVL2 | 0.655266 | 4 | 0 | 3 |
| PABPC1L | NUP155 | 0.655189 | 4 | 0 | 4 |
For details and further investigation, click here
