SEMA4F

 

Full name: ssemaphorin 4F Alias Symbol: SEMAW
Type: protein-coding gene Cytoband: 2p13.1
Entrez ID: 10505 HGNC ID: HGNC:10734 Ensembl Gene: ENSG00000135622 OMIM ID: 603706
Drug and gene relationship at DGIdb

 

SEMA4F involved pathways:

KEGG pathway Description View
hsa04360Axon guidance

 

Expression of SEMA4F:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SEMA4F 10505 210124_x_at 0.7660 0.0510
GSE20347 SEMA4F 10505 210124_x_at 0.7171 0.0000
GSE23400 SEMA4F 10505 210124_x_at 0.2732 0.0000
GSE26886 SEMA4F 10505 210124_x_at 1.1649 0.0000
GSE29001 SEMA4F 10505 210124_x_at 0.5122 0.0083
GSE38129 SEMA4F 10505 210124_x_at 0.7282 0.0000
GSE45670 SEMA4F 10505 210124_x_at 0.7512 0.0001
GSE53622 SEMA4F 10505 65790 1.3931 0.0000
GSE53624 SEMA4F 10505 65790 1.3935 0.0000
GSE63941 SEMA4F 10505 210124_x_at -0.0132 0.9783
GSE77861 SEMA4F 10505 210124_x_at 0.4222 0.0091
GSE97050 SEMA4F 10505 A_23_P165608 0.6282 0.1785
SRP007169 SEMA4F 10505 RNAseq 1.7065 0.0049
SRP008496 SEMA4F 10505 RNAseq 1.7234 0.0000
SRP064894 SEMA4F 10505 RNAseq 1.7134 0.0000
SRP133303 SEMA4F 10505 RNAseq 0.8143 0.0000
SRP159526 SEMA4F 10505 RNAseq 2.3946 0.0000
SRP193095 SEMA4F 10505 RNAseq 1.1887 0.0000
SRP219564 SEMA4F 10505 RNAseq 1.4718 0.0001
TCGA SEMA4F 10505 RNAseq 0.3247 0.0015

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by SEMA4F expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SEMA4F:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SEMA4F 10505 9 2 19
GSE20123 SEMA4F 10505 10 2 18
GSE43470 SEMA4F 10505 4 0 39
GSE46452 SEMA4F 10505 2 3 54
GSE47630 SEMA4F 10505 7 0 33
GSE54993 SEMA4F 10505 0 6 64
GSE54994 SEMA4F 10505 10 0 43
GSE60625 SEMA4F 10505 0 3 8
GSE74703 SEMA4F 10505 4 0 32
GSE74704 SEMA4F 10505 8 0 12
TCGA SEMA4F 10505 37 2 57

Total number of gains: 91; Total number of losses: 18; Total Number of normals: 379.  

 

Somatic mutations of SEMA4F:

 

Generating mutation plots.

 

Highly correlated genes for SEMA4F:

 

Showing top 20/1837 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SEMA4FWDR540.776924707
SEMA4FXPR10.764106606
SEMA4FKLF130.762112303
SEMA4FSPRR2G0.761325303
SEMA4FFMNL20.758221606
SEMA4FLPCAT10.7521861009
SEMA4FKNSTRN0.747558606
SEMA4FUBE2T0.740805707
SEMA4FGNPNAT10.728198303
SEMA4FSNAP470.725514303
SEMA4FKRTCAP20.721829303
SEMA4FHOXC90.721403404
SEMA4FHOXB70.7169811011
SEMA4FCTHRC10.716451807
SEMA4FGPR850.712737303
SEMA4FTTYH30.711995707
SEMA4FMED300.711055606
SEMA4FCD2760.710426605
SEMA4FACVR1C0.709534404
SEMA4FTMEM1380.709023505

For details and further investigation, click here