| Full name: SH3 domain containing 19 | Alias Symbol: DKFZp434D0215|EVE1|EBP|Kryn|SH3P19|Eve-1 | ||
| Type: protein-coding gene | Cytoband: 4q31.3 | ||
| Entrez ID: 152503 | HGNC ID: HGNC:30418 | Ensembl Gene: ENSG00000109686 | OMIM ID: 608674 |
| Drug and gene relationship at DGIdb | |||
Expression of SH3D19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3D19 | 152503 | 225162_at | -0.4369 | 0.5327 | |
| GSE26886 | SH3D19 | 152503 | 225162_at | -1.2550 | 0.0000 | |
| GSE45670 | SH3D19 | 152503 | 225162_at | -0.8612 | 0.0000 | |
| GSE53622 | SH3D19 | 152503 | 61087 | -1.0295 | 0.0000 | |
| GSE53624 | SH3D19 | 152503 | 61087 | -1.1726 | 0.0000 | |
| GSE63941 | SH3D19 | 152503 | 225162_at | -2.0563 | 0.0000 | |
| GSE77861 | SH3D19 | 152503 | 225162_at | -0.4172 | 0.1229 | |
| GSE97050 | SH3D19 | 152503 | A_23_P33364 | -0.5785 | 0.1399 | |
| SRP007169 | SH3D19 | 152503 | RNAseq | -0.9533 | 0.0726 | |
| SRP008496 | SH3D19 | 152503 | RNAseq | -1.1436 | 0.0005 | |
| SRP064894 | SH3D19 | 152503 | RNAseq | -0.9331 | 0.0009 | |
| SRP133303 | SH3D19 | 152503 | RNAseq | -0.2432 | 0.3846 | |
| SRP159526 | SH3D19 | 152503 | RNAseq | -0.8818 | 0.0051 | |
| SRP193095 | SH3D19 | 152503 | RNAseq | -0.8613 | 0.0000 | |
| SRP219564 | SH3D19 | 152503 | RNAseq | -0.8835 | 0.1118 | |
| TCGA | SH3D19 | 152503 | RNAseq | -0.2026 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SH3D19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH3D19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3D19 | 152503 | 1 | 13 | 16 | |
| GSE20123 | SH3D19 | 152503 | 1 | 13 | 16 | |
| GSE43470 | SH3D19 | 152503 | 0 | 14 | 29 | |
| GSE46452 | SH3D19 | 152503 | 1 | 36 | 22 | |
| GSE47630 | SH3D19 | 152503 | 0 | 23 | 17 | |
| GSE54993 | SH3D19 | 152503 | 10 | 0 | 60 | |
| GSE54994 | SH3D19 | 152503 | 1 | 12 | 40 | |
| GSE60625 | SH3D19 | 152503 | 0 | 1 | 10 | |
| GSE74703 | SH3D19 | 152503 | 0 | 12 | 24 | |
| GSE74704 | SH3D19 | 152503 | 0 | 7 | 13 | |
| TCGA | SH3D19 | 152503 | 10 | 35 | 51 |
Total number of gains: 24; Total number of losses: 166; Total Number of normals: 298.
Somatic mutations of SH3D19:
Generating mutation plots.
Highly correlated genes for SH3D19:
Showing top 20/1431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3D19 | CLEC3B | 0.779106 | 3 | 0 | 3 |
| SH3D19 | CYP21A2 | 0.774201 | 3 | 0 | 3 |
| SH3D19 | CHRDL1 | 0.770736 | 3 | 0 | 3 |
| SH3D19 | KAT2B | 0.768949 | 7 | 0 | 7 |
| SH3D19 | UTRN | 0.766413 | 4 | 0 | 4 |
| SH3D19 | FCER1A | 0.765268 | 5 | 0 | 5 |
| SH3D19 | C7 | 0.759065 | 4 | 0 | 4 |
| SH3D19 | RAP1A | 0.752859 | 7 | 0 | 7 |
| SH3D19 | EXOC6B | 0.749453 | 3 | 0 | 3 |
| SH3D19 | FAM214A | 0.749295 | 5 | 0 | 5 |
| SH3D19 | SLC2A4 | 0.746845 | 3 | 0 | 3 |
| SH3D19 | LMOD1 | 0.744594 | 5 | 0 | 5 |
| SH3D19 | ZNF407 | 0.743656 | 3 | 0 | 3 |
| SH3D19 | CAB39L | 0.74294 | 7 | 0 | 6 |
| SH3D19 | MXI1 | 0.738668 | 5 | 0 | 5 |
| SH3D19 | ARHGEF10L | 0.736313 | 6 | 0 | 6 |
| SH3D19 | ACOT12 | 0.734637 | 4 | 0 | 4 |
| SH3D19 | CBX7 | 0.734615 | 4 | 0 | 4 |
| SH3D19 | TMOD3 | 0.733575 | 5 | 0 | 5 |
| SH3D19 | SLC12A6 | 0.733015 | 3 | 0 | 3 |
For details and further investigation, click here
