| Full name: Meis homeobox 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 4211 | HGNC ID: HGNC:7000 | Ensembl Gene: ENSG00000143995 | OMIM ID: 601739 |
| Drug and gene relationship at DGIdb | |||
Expression of MEIS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEIS1 | 4211 | 204069_at | -1.4448 | 0.0523 | |
| GSE20347 | MEIS1 | 4211 | 204069_at | -1.3114 | 0.0000 | |
| GSE23400 | MEIS1 | 4211 | 204069_at | -0.9944 | 0.0000 | |
| GSE26886 | MEIS1 | 4211 | 204069_at | -1.8060 | 0.0000 | |
| GSE29001 | MEIS1 | 4211 | 204069_at | -1.3826 | 0.0000 | |
| GSE38129 | MEIS1 | 4211 | 204069_at | -1.4100 | 0.0000 | |
| GSE45670 | MEIS1 | 4211 | 204069_at | -1.0920 | 0.0005 | |
| GSE53622 | MEIS1 | 4211 | 42103 | -1.3706 | 0.0000 | |
| GSE53624 | MEIS1 | 4211 | 42103 | -1.4349 | 0.0000 | |
| GSE63941 | MEIS1 | 4211 | 204069_at | -2.4351 | 0.0004 | |
| GSE77861 | MEIS1 | 4211 | 204069_at | -1.4391 | 0.0007 | |
| GSE97050 | MEIS1 | 4211 | A_24_P319736 | -1.2985 | 0.0871 | |
| SRP007169 | MEIS1 | 4211 | RNAseq | -1.6154 | 0.0010 | |
| SRP008496 | MEIS1 | 4211 | RNAseq | -1.4747 | 0.0000 | |
| SRP064894 | MEIS1 | 4211 | RNAseq | -0.7640 | 0.0036 | |
| SRP133303 | MEIS1 | 4211 | RNAseq | -0.9069 | 0.0002 | |
| SRP159526 | MEIS1 | 4211 | RNAseq | -0.9503 | 0.0434 | |
| SRP193095 | MEIS1 | 4211 | RNAseq | -0.8293 | 0.0001 | |
| SRP219564 | MEIS1 | 4211 | RNAseq | -0.4648 | 0.5085 | |
| TCGA | MEIS1 | 4211 | RNAseq | -0.2140 | 0.0387 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by MEIS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEIS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEIS1 | 4211 | 13 | 0 | 17 | |
| GSE20123 | MEIS1 | 4211 | 12 | 0 | 18 | |
| GSE43470 | MEIS1 | 4211 | 6 | 0 | 37 | |
| GSE46452 | MEIS1 | 4211 | 2 | 3 | 54 | |
| GSE47630 | MEIS1 | 4211 | 8 | 0 | 32 | |
| GSE54993 | MEIS1 | 4211 | 0 | 6 | 64 | |
| GSE54994 | MEIS1 | 4211 | 12 | 0 | 41 | |
| GSE60625 | MEIS1 | 4211 | 0 | 3 | 8 | |
| GSE74703 | MEIS1 | 4211 | 6 | 0 | 30 | |
| GSE74704 | MEIS1 | 4211 | 10 | 0 | 10 | |
| TCGA | MEIS1 | 4211 | 36 | 2 | 58 |
Total number of gains: 105; Total number of losses: 14; Total Number of normals: 369.
Somatic mutations of MEIS1:
Generating mutation plots.
Highly correlated genes for MEIS1:
Showing top 20/1827 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEIS1 | NFIA | 0.844246 | 7 | 0 | 7 |
| MEIS1 | EIF4E3 | 0.825023 | 7 | 0 | 7 |
| MEIS1 | CYP21A2 | 0.815888 | 3 | 0 | 3 |
| MEIS1 | HLF | 0.806451 | 11 | 0 | 11 |
| MEIS1 | SORCS1 | 0.804884 | 4 | 0 | 4 |
| MEIS1 | CLEC3B | 0.803347 | 3 | 0 | 3 |
| MEIS1 | ANGPTL1 | 0.798254 | 6 | 0 | 6 |
| MEIS1 | SORBS2 | 0.793716 | 11 | 0 | 11 |
| MEIS1 | SHROOM3 | 0.790314 | 7 | 0 | 7 |
| MEIS1 | SNORA68 | 0.784865 | 4 | 0 | 4 |
| MEIS1 | MRVI1 | 0.78167 | 6 | 0 | 5 |
| MEIS1 | NEGR1 | 0.772804 | 6 | 0 | 6 |
| MEIS1 | KIAA1211L | 0.771371 | 6 | 0 | 6 |
| MEIS1 | GPD1L | 0.77127 | 12 | 0 | 11 |
| MEIS1 | XKR4 | 0.767537 | 5 | 0 | 5 |
| MEIS1 | KCNB1 | 0.765421 | 5 | 0 | 4 |
| MEIS1 | CTTNBP2 | 0.764168 | 7 | 0 | 7 |
| MEIS1 | HMHB1 | 0.763284 | 3 | 0 | 3 |
| MEIS1 | MAMDC2 | 0.763114 | 7 | 0 | 7 |
| MEIS1 | MTMR10 | 0.762691 | 8 | 0 | 7 |
For details and further investigation, click here
