| Full name: repulsive guidance molecule BMP co-receptor a | Alias Symbol: RGM|RGMa | ||
| Type: protein-coding gene | Cytoband: 15q26.1 | ||
| Entrez ID: 56963 | HGNC ID: HGNC:30308 | Ensembl Gene: ENSG00000182175 | OMIM ID: 607362 |
| Drug and gene relationship at DGIdb | |||
Expression of RGMA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGMA | 56963 | 223468_s_at | -0.9192 | 0.3970 | |
| GSE26886 | RGMA | 56963 | 223468_s_at | -1.5009 | 0.0000 | |
| GSE45670 | RGMA | 56963 | 223468_s_at | -0.8234 | 0.0102 | |
| GSE53622 | RGMA | 56963 | 23710 | -1.3623 | 0.0000 | |
| GSE53624 | RGMA | 56963 | 23710 | -1.2346 | 0.0000 | |
| GSE63941 | RGMA | 56963 | 223468_s_at | 0.2650 | 0.7071 | |
| GSE77861 | RGMA | 56963 | 223468_s_at | -0.5784 | 0.0802 | |
| GSE97050 | RGMA | 56963 | A_23_P372308 | -0.7211 | 0.2987 | |
| SRP007169 | RGMA | 56963 | RNAseq | -0.5159 | 0.4664 | |
| SRP008496 | RGMA | 56963 | RNAseq | -1.1571 | 0.0228 | |
| SRP064894 | RGMA | 56963 | RNAseq | -0.4156 | 0.2138 | |
| SRP133303 | RGMA | 56963 | RNAseq | -1.1621 | 0.0087 | |
| SRP159526 | RGMA | 56963 | RNAseq | -0.4348 | 0.4269 | |
| SRP193095 | RGMA | 56963 | RNAseq | -0.9508 | 0.0039 | |
| SRP219564 | RGMA | 56963 | RNAseq | -0.7727 | 0.4660 | |
| TCGA | RGMA | 56963 | RNAseq | -0.0992 | 0.4839 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by RGMA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGMA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGMA | 56963 | 8 | 2 | 20 | |
| GSE20123 | RGMA | 56963 | 8 | 2 | 20 | |
| GSE43470 | RGMA | 56963 | 4 | 4 | 35 | |
| GSE46452 | RGMA | 56963 | 3 | 7 | 49 | |
| GSE47630 | RGMA | 56963 | 8 | 11 | 21 | |
| GSE54993 | RGMA | 56963 | 4 | 6 | 60 | |
| GSE54994 | RGMA | 56963 | 8 | 7 | 38 | |
| GSE60625 | RGMA | 56963 | 4 | 0 | 7 | |
| GSE74703 | RGMA | 56963 | 3 | 3 | 30 | |
| GSE74704 | RGMA | 56963 | 3 | 3 | 14 | |
| TCGA | RGMA | 56963 | 17 | 12 | 67 |
Total number of gains: 70; Total number of losses: 57; Total Number of normals: 361.
Somatic mutations of RGMA:
Generating mutation plots.
Highly correlated genes for RGMA:
Showing top 20/811 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGMA | ID4 | 0.724497 | 5 | 0 | 5 |
| RGMA | GALNT12 | 0.712208 | 7 | 0 | 7 |
| RGMA | ZBTB7C | 0.699312 | 7 | 0 | 7 |
| RGMA | PARP16 | 0.697819 | 4 | 0 | 4 |
| RGMA | BAG1 | 0.694882 | 4 | 0 | 4 |
| RGMA | NTN1 | 0.690733 | 6 | 0 | 6 |
| RGMA | SLC9A9 | 0.685022 | 7 | 0 | 7 |
| RGMA | CTTNBP2 | 0.682147 | 6 | 0 | 6 |
| RGMA | TLE2 | 0.677454 | 5 | 0 | 5 |
| RGMA | RAPGEFL1 | 0.6735 | 4 | 0 | 4 |
| RGMA | ZNF528 | 0.667491 | 4 | 0 | 4 |
| RGMA | LONRF2 | 0.665166 | 5 | 0 | 5 |
| RGMA | RAB11B-AS1 | 0.665077 | 4 | 0 | 4 |
| RGMA | SSBP3 | 0.664798 | 3 | 0 | 3 |
| RGMA | ZDHHC20 | 0.659409 | 3 | 0 | 3 |
| RGMA | GPD1L | 0.659206 | 7 | 0 | 7 |
| RGMA | RERE | 0.657724 | 3 | 0 | 3 |
| RGMA | NDUFB2 | 0.653809 | 3 | 0 | 3 |
| RGMA | ATP1A2 | 0.651834 | 5 | 0 | 5 |
| RGMA | ALDH9A1 | 0.647694 | 5 | 0 | 5 |
For details and further investigation, click here
