| Full name: cytohesin 4 | Alias Symbol: CYT4|cytohesin-4 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 27128 | HGNC ID: HGNC:9505 | Ensembl Gene: ENSG00000100055 | OMIM ID: 606514 |
| Drug and gene relationship at DGIdb | |||
CYTH4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04072 | Phospholipase D signaling pathway |
Expression of CYTH4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYTH4 | 27128 | 219183_s_at | 0.4604 | 0.3983 | |
| GSE20347 | CYTH4 | 27128 | 219183_s_at | 0.1404 | 0.3188 | |
| GSE23400 | CYTH4 | 27128 | 219183_s_at | -0.0164 | 0.6543 | |
| GSE26886 | CYTH4 | 27128 | 219183_s_at | 0.3373 | 0.0536 | |
| GSE29001 | CYTH4 | 27128 | 219183_s_at | 0.0392 | 0.7987 | |
| GSE38129 | CYTH4 | 27128 | 219183_s_at | -0.0418 | 0.7738 | |
| GSE45670 | CYTH4 | 27128 | 219183_s_at | 0.1281 | 0.2793 | |
| GSE53622 | CYTH4 | 27128 | 30725 | 0.1788 | 0.2020 | |
| GSE53624 | CYTH4 | 27128 | 106620 | 0.4471 | 0.0000 | |
| GSE63941 | CYTH4 | 27128 | 219183_s_at | 0.1591 | 0.3709 | |
| GSE77861 | CYTH4 | 27128 | 219183_s_at | -0.0988 | 0.3462 | |
| GSE97050 | CYTH4 | 27128 | A_24_P74559 | 0.5948 | 0.1802 | |
| SRP007169 | CYTH4 | 27128 | RNAseq | 2.4122 | 0.0046 | |
| SRP008496 | CYTH4 | 27128 | RNAseq | 1.9627 | 0.0018 | |
| SRP064894 | CYTH4 | 27128 | RNAseq | 0.9178 | 0.0020 | |
| SRP133303 | CYTH4 | 27128 | RNAseq | 0.2110 | 0.4038 | |
| SRP159526 | CYTH4 | 27128 | RNAseq | -0.1761 | 0.7832 | |
| SRP193095 | CYTH4 | 27128 | RNAseq | 1.0863 | 0.0001 | |
| SRP219564 | CYTH4 | 27128 | RNAseq | 0.8770 | 0.0422 | |
| TCGA | CYTH4 | 27128 | RNAseq | 0.1886 | 0.2158 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CYTH4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYTH4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYTH4 | 27128 | 6 | 6 | 18 | |
| GSE20123 | CYTH4 | 27128 | 6 | 5 | 19 | |
| GSE43470 | CYTH4 | 27128 | 4 | 6 | 33 | |
| GSE46452 | CYTH4 | 27128 | 32 | 2 | 25 | |
| GSE47630 | CYTH4 | 27128 | 8 | 5 | 27 | |
| GSE54993 | CYTH4 | 27128 | 3 | 6 | 61 | |
| GSE54994 | CYTH4 | 27128 | 9 | 8 | 36 | |
| GSE60625 | CYTH4 | 27128 | 5 | 0 | 6 | |
| GSE74703 | CYTH4 | 27128 | 4 | 4 | 28 | |
| GSE74704 | CYTH4 | 27128 | 3 | 2 | 15 | |
| TCGA | CYTH4 | 27128 | 27 | 16 | 53 |
Total number of gains: 107; Total number of losses: 60; Total Number of normals: 321.
Somatic mutations of CYTH4:
Generating mutation plots.
Highly correlated genes for CYTH4:
Showing top 20/421 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYTH4 | LAIR1 | 0.775287 | 8 | 0 | 8 |
| CYTH4 | C19orf38 | 0.747863 | 3 | 0 | 3 |
| CYTH4 | PARVG | 0.741571 | 6 | 0 | 5 |
| CYTH4 | SNX20 | 0.711336 | 6 | 0 | 6 |
| CYTH4 | KIAA0319L | 0.708393 | 3 | 0 | 3 |
| CYTH4 | TMEM106A | 0.701597 | 4 | 0 | 4 |
| CYTH4 | LILRB1 | 0.700356 | 9 | 0 | 7 |
| CYTH4 | CCR5 | 0.6997 | 8 | 0 | 8 |
| CYTH4 | PTPN7 | 0.692615 | 9 | 0 | 8 |
| CYTH4 | SPATA13 | 0.690747 | 4 | 0 | 4 |
| CYTH4 | BIN2 | 0.68526 | 9 | 0 | 8 |
| CYTH4 | OCIAD2 | 0.683044 | 3 | 0 | 3 |
| CYTH4 | CR1L | 0.680448 | 5 | 0 | 5 |
| CYTH4 | CTSZ | 0.679189 | 4 | 0 | 4 |
| CYTH4 | NAIP | 0.678196 | 4 | 0 | 3 |
| CYTH4 | SIGLEC1 | 0.669422 | 8 | 0 | 6 |
| CYTH4 | SLA | 0.668288 | 11 | 0 | 9 |
| CYTH4 | A1BG | 0.66658 | 3 | 0 | 3 |
| CYTH4 | NNMT | 0.665924 | 3 | 0 | 3 |
| CYTH4 | FCGR3A | 0.66566 | 3 | 0 | 3 |
For details and further investigation, click here
