| Full name: complement C1q binding protein | Alias Symbol: gC1Q-R|gC1qR|p32|SF2p32 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 708 | HGNC ID: HGNC:1243 | Ensembl Gene: ENSG00000108561 | OMIM ID: 601269 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
C1QBP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05168 | Herpes simplex infection |
Expression of C1QBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1QBP | 708 | 208910_s_at | 0.3464 | 0.3196 | |
| GSE20347 | C1QBP | 708 | 214214_s_at | 0.2728 | 0.2212 | |
| GSE23400 | C1QBP | 708 | 208910_s_at | 0.6650 | 0.0000 | |
| GSE26886 | C1QBP | 708 | 214214_s_at | 0.3087 | 0.0814 | |
| GSE29001 | C1QBP | 708 | 214214_s_at | 0.3112 | 0.5107 | |
| GSE38129 | C1QBP | 708 | 214214_s_at | 0.5283 | 0.0060 | |
| GSE45670 | C1QBP | 708 | 208910_s_at | 0.2779 | 0.1747 | |
| GSE53622 | C1QBP | 708 | 81040 | 0.0179 | 0.7150 | |
| GSE53624 | C1QBP | 708 | 81040 | 0.1945 | 0.0000 | |
| GSE63941 | C1QBP | 708 | 208910_s_at | 0.8072 | 0.0662 | |
| GSE77861 | C1QBP | 708 | 208910_s_at | 0.3754 | 0.1761 | |
| GSE97050 | C1QBP | 708 | A_23_P370434 | 0.3946 | 0.2307 | |
| SRP007169 | C1QBP | 708 | RNAseq | 0.0996 | 0.8073 | |
| SRP008496 | C1QBP | 708 | RNAseq | 0.0202 | 0.9313 | |
| SRP064894 | C1QBP | 708 | RNAseq | 0.1557 | 0.4177 | |
| SRP133303 | C1QBP | 708 | RNAseq | 0.1404 | 0.4479 | |
| SRP159526 | C1QBP | 708 | RNAseq | 0.5191 | 0.1283 | |
| SRP193095 | C1QBP | 708 | RNAseq | 0.0739 | 0.6501 | |
| SRP219564 | C1QBP | 708 | RNAseq | 0.6436 | 0.1949 | |
| TCGA | C1QBP | 708 | RNAseq | 0.2141 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C1QBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1QBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1QBP | 708 | 5 | 2 | 23 | |
| GSE20123 | C1QBP | 708 | 5 | 3 | 22 | |
| GSE43470 | C1QBP | 708 | 1 | 6 | 36 | |
| GSE46452 | C1QBP | 708 | 34 | 1 | 24 | |
| GSE47630 | C1QBP | 708 | 7 | 1 | 32 | |
| GSE54993 | C1QBP | 708 | 4 | 3 | 63 | |
| GSE54994 | C1QBP | 708 | 5 | 8 | 40 | |
| GSE60625 | C1QBP | 708 | 4 | 0 | 7 | |
| GSE74703 | C1QBP | 708 | 1 | 3 | 32 | |
| GSE74704 | C1QBP | 708 | 3 | 1 | 16 | |
| TCGA | C1QBP | 708 | 18 | 20 | 58 |
Total number of gains: 87; Total number of losses: 48; Total Number of normals: 353.
Somatic mutations of C1QBP:
Generating mutation plots.
Highly correlated genes for C1QBP:
Showing top 20/1134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1QBP | HORMAD1 | 0.766037 | 3 | 0 | 3 |
| C1QBP | VPS35 | 0.755235 | 3 | 0 | 3 |
| C1QBP | ROMO1 | 0.748724 | 3 | 0 | 3 |
| C1QBP | TRUB1 | 0.746078 | 4 | 0 | 4 |
| C1QBP | REST | 0.741803 | 3 | 0 | 3 |
| C1QBP | SRSF6 | 0.738095 | 3 | 0 | 3 |
| C1QBP | PATL1 | 0.736896 | 3 | 0 | 3 |
| C1QBP | KREMEN1 | 0.729873 | 3 | 0 | 3 |
| C1QBP | PLEKHF2 | 0.726171 | 3 | 0 | 3 |
| C1QBP | C12orf45 | 0.722314 | 4 | 0 | 4 |
| C1QBP | PPIL1 | 0.721207 | 4 | 0 | 3 |
| C1QBP | ZNF267 | 0.720713 | 4 | 0 | 4 |
| C1QBP | THAP10 | 0.717725 | 4 | 0 | 3 |
| C1QBP | TP53RK | 0.712554 | 3 | 0 | 3 |
| C1QBP | NFKB1 | 0.70647 | 4 | 0 | 4 |
| C1QBP | AMMECR1 | 0.698016 | 3 | 0 | 3 |
| C1QBP | PDE8A | 0.694617 | 4 | 0 | 4 |
| C1QBP | TRMT6 | 0.692593 | 6 | 0 | 5 |
| C1QBP | FMNL3 | 0.691625 | 3 | 0 | 3 |
| C1QBP | C18orf54 | 0.691507 | 3 | 0 | 3 |
For details and further investigation, click here
