| Full name: cytochrome b5 domain containing 2 | Alias Symbol: MGC32124 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 124936 | HGNC ID: HGNC:28471 | Ensembl Gene: ENSG00000167740 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CYB5D2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYB5D2 | 124936 | 225804_at | -0.9202 | 0.0327 | |
| GSE26886 | CYB5D2 | 124936 | 225804_at | -0.0871 | 0.7609 | |
| GSE45670 | CYB5D2 | 124936 | 225804_at | -0.2008 | 0.1837 | |
| GSE53622 | CYB5D2 | 124936 | 40266 | -0.0880 | 0.1812 | |
| GSE53624 | CYB5D2 | 124936 | 40266 | -0.1087 | 0.1224 | |
| GSE63941 | CYB5D2 | 124936 | 225804_at | -0.6198 | 0.2981 | |
| GSE77861 | CYB5D2 | 124936 | 225804_at | -0.2523 | 0.4713 | |
| GSE97050 | CYB5D2 | 124936 | A_24_P228026 | 0.0854 | 0.7720 | |
| SRP007169 | CYB5D2 | 124936 | RNAseq | -0.9502 | 0.0342 | |
| SRP008496 | CYB5D2 | 124936 | RNAseq | -0.3592 | 0.2564 | |
| SRP064894 | CYB5D2 | 124936 | RNAseq | 0.0997 | 0.7113 | |
| SRP133303 | CYB5D2 | 124936 | RNAseq | -0.5491 | 0.0054 | |
| SRP159526 | CYB5D2 | 124936 | RNAseq | -0.1839 | 0.5642 | |
| SRP193095 | CYB5D2 | 124936 | RNAseq | -0.4279 | 0.0006 | |
| SRP219564 | CYB5D2 | 124936 | RNAseq | 0.2019 | 0.6486 | |
| TCGA | CYB5D2 | 124936 | RNAseq | -0.3561 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYB5D2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYB5D2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYB5D2 | 124936 | 5 | 2 | 23 | |
| GSE20123 | CYB5D2 | 124936 | 5 | 3 | 22 | |
| GSE43470 | CYB5D2 | 124936 | 1 | 6 | 36 | |
| GSE46452 | CYB5D2 | 124936 | 34 | 1 | 24 | |
| GSE47630 | CYB5D2 | 124936 | 7 | 1 | 32 | |
| GSE54993 | CYB5D2 | 124936 | 4 | 3 | 63 | |
| GSE54994 | CYB5D2 | 124936 | 5 | 9 | 39 | |
| GSE60625 | CYB5D2 | 124936 | 4 | 0 | 7 | |
| GSE74703 | CYB5D2 | 124936 | 1 | 3 | 32 | |
| GSE74704 | CYB5D2 | 124936 | 3 | 1 | 16 | |
| TCGA | CYB5D2 | 124936 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of CYB5D2:
Generating mutation plots.
Highly correlated genes for CYB5D2:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYB5D2 | PAX7 | 0.756578 | 3 | 0 | 3 |
| CYB5D2 | ADAMTSL4 | 0.695633 | 3 | 0 | 3 |
| CYB5D2 | PAFAH1B1 | 0.694113 | 3 | 0 | 3 |
| CYB5D2 | ROBO2 | 0.676716 | 4 | 0 | 4 |
| CYB5D2 | FRMD1 | 0.674619 | 3 | 0 | 3 |
| CYB5D2 | ADRA2A | 0.667831 | 3 | 0 | 3 |
| CYB5D2 | GSTM5 | 0.662112 | 4 | 0 | 3 |
| CYB5D2 | GALK1 | 0.658427 | 3 | 0 | 3 |
| CYB5D2 | PLA2G12B | 0.655459 | 3 | 0 | 3 |
| CYB5D2 | PPP2R5A | 0.654798 | 3 | 0 | 3 |
| CYB5D2 | ERCC5 | 0.645985 | 3 | 0 | 3 |
| CYB5D2 | CHRD | 0.636459 | 3 | 0 | 3 |
| CYB5D2 | LCN8 | 0.626697 | 3 | 0 | 3 |
| CYB5D2 | ZBTB45 | 0.624528 | 3 | 0 | 3 |
| CYB5D2 | ENPP1 | 0.6194 | 3 | 0 | 3 |
| CYB5D2 | THBS3 | 0.61909 | 3 | 0 | 3 |
| CYB5D2 | SLC25A48 | 0.615264 | 4 | 0 | 3 |
| CYB5D2 | FCN3 | 0.614098 | 3 | 0 | 3 |
| CYB5D2 | FBXO38 | 0.613898 | 3 | 0 | 3 |
| CYB5D2 | MUC2 | 0.613468 | 3 | 0 | 3 |
For details and further investigation, click here
