| Full name: calcium/calmodulin dependent protein kinase II inhibitor 1 | Alias Symbol: CaMKIINalpha | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 55450 | HGNC ID: HGNC:24190 | Ensembl Gene: ENSG00000162545 | OMIM ID: 614986 |
| Drug and gene relationship at DGIdb | |||
Expression of CAMK2N1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAMK2N1 | 55450 | 218309_at | -1.5655 | 0.0426 | |
| GSE20347 | CAMK2N1 | 55450 | 218309_at | -2.3880 | 0.0000 | |
| GSE23400 | CAMK2N1 | 55450 | 218309_at | -1.3540 | 0.0000 | |
| GSE26886 | CAMK2N1 | 55450 | 218309_at | -0.9062 | 0.0363 | |
| GSE29001 | CAMK2N1 | 55450 | 218309_at | -2.1498 | 0.0002 | |
| GSE38129 | CAMK2N1 | 55450 | 218309_at | -2.0297 | 0.0000 | |
| GSE45670 | CAMK2N1 | 55450 | 218309_at | -1.2847 | 0.0024 | |
| GSE53622 | CAMK2N1 | 55450 | 2599 | -1.1619 | 0.0000 | |
| GSE53624 | CAMK2N1 | 55450 | 2599 | -1.1268 | 0.0000 | |
| GSE63941 | CAMK2N1 | 55450 | 218309_at | -2.9896 | 0.0067 | |
| GSE77861 | CAMK2N1 | 55450 | 218309_at | -2.4127 | 0.0010 | |
| GSE97050 | CAMK2N1 | 55450 | A_23_P11800 | -1.5027 | 0.0530 | |
| SRP007169 | CAMK2N1 | 55450 | RNAseq | -4.5554 | 0.0000 | |
| SRP008496 | CAMK2N1 | 55450 | RNAseq | -3.9072 | 0.0000 | |
| SRP064894 | CAMK2N1 | 55450 | RNAseq | -1.7253 | 0.0000 | |
| SRP133303 | CAMK2N1 | 55450 | RNAseq | -0.5073 | 0.1896 | |
| SRP159526 | CAMK2N1 | 55450 | RNAseq | -2.5209 | 0.0000 | |
| SRP193095 | CAMK2N1 | 55450 | RNAseq | -2.1129 | 0.0000 | |
| SRP219564 | CAMK2N1 | 55450 | RNAseq | -1.1479 | 0.0096 | |
| TCGA | CAMK2N1 | 55450 | RNAseq | -0.2107 | 0.1376 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by CAMK2N1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAMK2N1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAMK2N1 | 55450 | 0 | 5 | 25 | |
| GSE20123 | CAMK2N1 | 55450 | 0 | 4 | 26 | |
| GSE43470 | CAMK2N1 | 55450 | 0 | 8 | 35 | |
| GSE46452 | CAMK2N1 | 55450 | 5 | 1 | 53 | |
| GSE47630 | CAMK2N1 | 55450 | 8 | 3 | 29 | |
| GSE54993 | CAMK2N1 | 55450 | 3 | 1 | 66 | |
| GSE54994 | CAMK2N1 | 55450 | 11 | 4 | 38 | |
| GSE60625 | CAMK2N1 | 55450 | 0 | 0 | 11 | |
| GSE74703 | CAMK2N1 | 55450 | 0 | 5 | 31 | |
| GSE74704 | CAMK2N1 | 55450 | 0 | 0 | 20 | |
| TCGA | CAMK2N1 | 55450 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of CAMK2N1:
Generating mutation plots.
Highly correlated genes for CAMK2N1:
Showing top 20/1258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAMK2N1 | ARHGAP10 | 0.765689 | 12 | 0 | 12 |
| CAMK2N1 | ABLIM3 | 0.765091 | 11 | 0 | 11 |
| CAMK2N1 | SECISBP2L | 0.731598 | 12 | 0 | 12 |
| CAMK2N1 | PINK1 | 0.730116 | 10 | 0 | 9 |
| CAMK2N1 | RAP1A | 0.730078 | 11 | 0 | 11 |
| CAMK2N1 | CITED2 | 0.726558 | 12 | 0 | 12 |
| CAMK2N1 | CNN3 | 0.725368 | 9 | 0 | 9 |
| CAMK2N1 | CAST | 0.724671 | 11 | 0 | 11 |
| CAMK2N1 | PPP1R3C | 0.720393 | 12 | 0 | 11 |
| CAMK2N1 | SERPINB6 | 0.712121 | 12 | 0 | 10 |
| CAMK2N1 | RBPMS | 0.710667 | 12 | 0 | 12 |
| CAMK2N1 | SORBS2 | 0.705418 | 11 | 0 | 11 |
| CAMK2N1 | ZNF662 | 0.705097 | 8 | 0 | 8 |
| CAMK2N1 | TAX1BP1 | 0.704845 | 11 | 0 | 10 |
| CAMK2N1 | KAT2B | 0.703803 | 12 | 0 | 11 |
| CAMK2N1 | CRYL1 | 0.701589 | 10 | 0 | 10 |
| CAMK2N1 | OSBPL10 | 0.70154 | 9 | 0 | 8 |
| CAMK2N1 | ECM1 | 0.699552 | 11 | 0 | 11 |
| CAMK2N1 | GYS2 | 0.69916 | 10 | 0 | 9 |
| CAMK2N1 | MGLL | 0.69828 | 12 | 0 | 12 |
For details and further investigation, click here
