| Full name: protocadherin 17 | Alias Symbol: PCDH68|PCH68 | ||
| Type: protein-coding gene | Cytoband: 13q21.1 | ||
| Entrez ID: 27253 | HGNC ID: HGNC:14267 | Ensembl Gene: ENSG00000118946 | OMIM ID: 611760 |
| Drug and gene relationship at DGIdb | |||
Expression of PCDH17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCDH17 | 27253 | 205656_at | 0.4113 | 0.5455 | |
| GSE20347 | PCDH17 | 27253 | 205656_at | 0.4353 | 0.0017 | |
| GSE23400 | PCDH17 | 27253 | 205656_at | 0.2968 | 0.0000 | |
| GSE26886 | PCDH17 | 27253 | 205656_at | 0.4599 | 0.0911 | |
| GSE29001 | PCDH17 | 27253 | 205656_at | 0.3552 | 0.1949 | |
| GSE38129 | PCDH17 | 27253 | 205656_at | 0.2964 | 0.0951 | |
| GSE45670 | PCDH17 | 27253 | 205656_at | 0.6067 | 0.0671 | |
| GSE53622 | PCDH17 | 27253 | 69832 | 0.6901 | 0.0000 | |
| GSE53624 | PCDH17 | 27253 | 69832 | 0.8299 | 0.0000 | |
| GSE63941 | PCDH17 | 27253 | 205656_at | 0.5918 | 0.3969 | |
| GSE77861 | PCDH17 | 27253 | 205656_at | 0.6598 | 0.0406 | |
| GSE97050 | PCDH17 | 27253 | A_24_P911906 | 0.2457 | 0.3660 | |
| SRP007169 | PCDH17 | 27253 | RNAseq | 3.5681 | 0.0000 | |
| SRP008496 | PCDH17 | 27253 | RNAseq | 3.1261 | 0.0000 | |
| SRP064894 | PCDH17 | 27253 | RNAseq | 1.7435 | 0.0000 | |
| SRP133303 | PCDH17 | 27253 | RNAseq | 0.6522 | 0.0086 | |
| SRP159526 | PCDH17 | 27253 | RNAseq | 1.4830 | 0.0003 | |
| SRP193095 | PCDH17 | 27253 | RNAseq | 1.4104 | 0.0000 | |
| SRP219564 | PCDH17 | 27253 | RNAseq | 0.8667 | 0.0803 | |
| TCGA | PCDH17 | 27253 | RNAseq | 0.0574 | 0.6639 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by PCDH17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCDH17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCDH17 | 27253 | 1 | 13 | 16 | |
| GSE20123 | PCDH17 | 27253 | 1 | 12 | 17 | |
| GSE43470 | PCDH17 | 27253 | 1 | 12 | 30 | |
| GSE46452 | PCDH17 | 27253 | 0 | 32 | 27 | |
| GSE47630 | PCDH17 | 27253 | 2 | 27 | 11 | |
| GSE54993 | PCDH17 | 27253 | 11 | 3 | 56 | |
| GSE54994 | PCDH17 | 27253 | 2 | 14 | 37 | |
| GSE60625 | PCDH17 | 27253 | 0 | 3 | 8 | |
| GSE74703 | PCDH17 | 27253 | 1 | 10 | 25 | |
| GSE74704 | PCDH17 | 27253 | 0 | 10 | 10 | |
| TCGA | PCDH17 | 27253 | 12 | 33 | 51 |
Total number of gains: 31; Total number of losses: 169; Total Number of normals: 288.
Somatic mutations of PCDH17:
Generating mutation plots.
Highly correlated genes for PCDH17:
Showing top 20/739 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCDH17 | NFKBID | 0.779122 | 3 | 0 | 3 |
| PCDH17 | SPIRE1 | 0.731457 | 3 | 0 | 3 |
| PCDH17 | HNRNPC | 0.70624 | 3 | 0 | 3 |
| PCDH17 | C20orf194 | 0.705183 | 3 | 0 | 3 |
| PCDH17 | SETDB1 | 0.701336 | 3 | 0 | 3 |
| PCDH17 | KCTD13 | 0.699161 | 3 | 0 | 3 |
| PCDH17 | TIPRL | 0.692276 | 3 | 0 | 3 |
| PCDH17 | NUP133 | 0.689668 | 3 | 0 | 3 |
| PCDH17 | CPT1A | 0.682335 | 3 | 0 | 3 |
| PCDH17 | MSTO1 | 0.678031 | 3 | 0 | 3 |
| PCDH17 | TM4SF18 | 0.67755 | 5 | 0 | 4 |
| PCDH17 | TMEM47 | 0.673794 | 3 | 0 | 3 |
| PCDH17 | CDADC1 | 0.673197 | 3 | 0 | 3 |
| PCDH17 | STRADA | 0.67167 | 4 | 0 | 3 |
| PCDH17 | ZNF461 | 0.670847 | 3 | 0 | 3 |
| PCDH17 | DGKH | 0.668267 | 4 | 0 | 3 |
| PCDH17 | CMPK2 | 0.667909 | 3 | 0 | 3 |
| PCDH17 | PIM2 | 0.663863 | 4 | 0 | 3 |
| PCDH17 | MRPL9 | 0.66282 | 3 | 0 | 3 |
| PCDH17 | EGFLAM | 0.662173 | 5 | 0 | 4 |
For details and further investigation, click here
