| Full name: cytidine/uridine monophosphate kinase 2 | Alias Symbol: TYKi|UMP-CMPK2|NDK | ||
| Type: protein-coding gene | Cytoband: 2p25.2 | ||
| Entrez ID: 129607 | HGNC ID: HGNC:27015 | Ensembl Gene: ENSG00000134326 | OMIM ID: 611787 |
| Drug and gene relationship at DGIdb | |||
Expression of CMPK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMPK2 | 129607 | 226702_at | 0.6130 | 0.6700 | |
| GSE26886 | CMPK2 | 129607 | 226702_at | 1.5212 | 0.0378 | |
| GSE45670 | CMPK2 | 129607 | 226702_at | 2.9353 | 0.0000 | |
| GSE53622 | CMPK2 | 129607 | 31383 | 1.4426 | 0.0000 | |
| GSE53624 | CMPK2 | 129607 | 31383 | 1.9249 | 0.0000 | |
| GSE63941 | CMPK2 | 129607 | 226702_at | 0.1509 | 0.9342 | |
| GSE77861 | CMPK2 | 129607 | 226702_at | 0.8080 | 0.0800 | |
| GSE97050 | CMPK2 | 129607 | A_33_P3401826 | 0.7690 | 0.1294 | |
| SRP007169 | CMPK2 | 129607 | RNAseq | 3.5893 | 0.0000 | |
| SRP064894 | CMPK2 | 129607 | RNAseq | 2.5852 | 0.0000 | |
| SRP133303 | CMPK2 | 129607 | RNAseq | 1.5668 | 0.0001 | |
| SRP193095 | CMPK2 | 129607 | RNAseq | 1.0502 | 0.0035 | |
| SRP219564 | CMPK2 | 129607 | RNAseq | 0.9164 | 0.3488 | |
| TCGA | CMPK2 | 129607 | RNAseq | 0.4168 | 0.0089 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by CMPK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CMPK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMPK2 | 129607 | 8 | 2 | 20 | |
| GSE20123 | CMPK2 | 129607 | 8 | 2 | 20 | |
| GSE43470 | CMPK2 | 129607 | 2 | 0 | 41 | |
| GSE46452 | CMPK2 | 129607 | 3 | 4 | 52 | |
| GSE47630 | CMPK2 | 129607 | 7 | 0 | 33 | |
| GSE54993 | CMPK2 | 129607 | 0 | 7 | 63 | |
| GSE54994 | CMPK2 | 129607 | 11 | 0 | 42 | |
| GSE60625 | CMPK2 | 129607 | 0 | 3 | 8 | |
| GSE74703 | CMPK2 | 129607 | 2 | 0 | 34 | |
| GSE74704 | CMPK2 | 129607 | 8 | 1 | 11 | |
| TCGA | CMPK2 | 129607 | 33 | 5 | 58 |
Total number of gains: 82; Total number of losses: 24; Total Number of normals: 382.
Somatic mutations of CMPK2:
Generating mutation plots.
Highly correlated genes for CMPK2:
Showing top 20/824 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMPK2 | IRF9 | 0.851865 | 3 | 0 | 3 |
| CMPK2 | IFI44 | 0.829936 | 8 | 0 | 8 |
| CMPK2 | RSAD2 | 0.829233 | 9 | 0 | 9 |
| CMPK2 | USP41 | 0.805686 | 3 | 0 | 3 |
| CMPK2 | FCGR3A | 0.782869 | 3 | 0 | 3 |
| CMPK2 | EPSTI1 | 0.780825 | 7 | 0 | 6 |
| CMPK2 | IFI35 | 0.775834 | 8 | 0 | 7 |
| CMPK2 | XAF1 | 0.775375 | 8 | 0 | 7 |
| CMPK2 | IFI44L | 0.768257 | 9 | 0 | 7 |
| CMPK2 | BST2 | 0.765896 | 7 | 0 | 6 |
| CMPK2 | UBE2L6 | 0.762886 | 7 | 0 | 6 |
| CMPK2 | STAT1 | 0.756103 | 8 | 0 | 7 |
| CMPK2 | IFIT1 | 0.753656 | 9 | 0 | 7 |
| CMPK2 | SUCNR1 | 0.753473 | 3 | 0 | 3 |
| CMPK2 | EIF2AK2 | 0.75339 | 7 | 0 | 7 |
| CMPK2 | DDX60 | 0.752264 | 9 | 0 | 7 |
| CMPK2 | USP18 | 0.750045 | 8 | 0 | 7 |
| CMPK2 | STAT2 | 0.749918 | 5 | 0 | 5 |
| CMPK2 | HERC5 | 0.747257 | 8 | 0 | 7 |
| CMPK2 | NCAPG | 0.740627 | 3 | 0 | 3 |
For details and further investigation, click here
