| Full name: eukaryotic translation initiation factor 1B | Alias Symbol: GC20 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 10289 | HGNC ID: HGNC:30792 | Ensembl Gene: ENSG00000114784 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EIF1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF1B | 10289 | 201738_at | -0.1787 | 0.6887 | |
| GSE20347 | EIF1B | 10289 | 201738_at | -0.0194 | 0.9310 | |
| GSE23400 | EIF1B | 10289 | 201738_at | 0.1500 | 0.1507 | |
| GSE26886 | EIF1B | 10289 | 201738_at | 0.6634 | 0.0002 | |
| GSE29001 | EIF1B | 10289 | 201738_at | 0.0142 | 0.9754 | |
| GSE38129 | EIF1B | 10289 | 201738_at | -0.1797 | 0.3518 | |
| GSE45670 | EIF1B | 10289 | 201738_at | -0.3377 | 0.0260 | |
| GSE53622 | EIF1B | 10289 | 131623 | -0.2298 | 0.0006 | |
| GSE53624 | EIF1B | 10289 | 131623 | -0.0675 | 0.3671 | |
| GSE63941 | EIF1B | 10289 | 201738_at | -0.6163 | 0.0846 | |
| GSE77861 | EIF1B | 10289 | 201738_at | -0.1050 | 0.6715 | |
| GSE97050 | EIF1B | 10289 | A_23_P6891 | -0.4211 | 0.1970 | |
| SRP007169 | EIF1B | 10289 | RNAseq | 0.5524 | 0.2214 | |
| SRP008496 | EIF1B | 10289 | RNAseq | 0.7244 | 0.0386 | |
| SRP064894 | EIF1B | 10289 | RNAseq | -0.0421 | 0.7940 | |
| SRP133303 | EIF1B | 10289 | RNAseq | -0.0617 | 0.6701 | |
| SRP159526 | EIF1B | 10289 | RNAseq | -0.0584 | 0.8382 | |
| SRP193095 | EIF1B | 10289 | RNAseq | -0.1646 | 0.1823 | |
| SRP219564 | EIF1B | 10289 | RNAseq | -0.2763 | 0.5395 | |
| TCGA | EIF1B | 10289 | RNAseq | -0.2284 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF1B | 10289 | 0 | 19 | 11 | |
| GSE20123 | EIF1B | 10289 | 0 | 19 | 11 | |
| GSE43470 | EIF1B | 10289 | 0 | 20 | 23 | |
| GSE46452 | EIF1B | 10289 | 2 | 17 | 40 | |
| GSE47630 | EIF1B | 10289 | 2 | 24 | 14 | |
| GSE54993 | EIF1B | 10289 | 7 | 2 | 61 | |
| GSE54994 | EIF1B | 10289 | 0 | 34 | 19 | |
| GSE60625 | EIF1B | 10289 | 5 | 0 | 6 | |
| GSE74703 | EIF1B | 10289 | 0 | 16 | 20 | |
| GSE74704 | EIF1B | 10289 | 0 | 13 | 7 | |
| TCGA | EIF1B | 10289 | 1 | 71 | 24 |
Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.
Somatic mutations of EIF1B:
Generating mutation plots.
Highly correlated genes for EIF1B:
Showing top 20/726 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF1B | METTL9 | 0.771819 | 3 | 0 | 3 |
| EIF1B | PSMD1 | 0.749602 | 3 | 0 | 3 |
| EIF1B | MRPS6 | 0.746251 | 3 | 0 | 3 |
| EIF1B | PHIP | 0.745197 | 3 | 0 | 3 |
| EIF1B | CBLL1 | 0.740082 | 3 | 0 | 3 |
| EIF1B | NENF | 0.737461 | 3 | 0 | 3 |
| EIF1B | ZCRB1 | 0.737059 | 3 | 0 | 3 |
| EIF1B | EIF4G2 | 0.721466 | 4 | 0 | 4 |
| EIF1B | ZBTB25 | 0.718213 | 3 | 0 | 3 |
| EIF1B | KAT5 | 0.715193 | 3 | 0 | 3 |
| EIF1B | INTS4 | 0.714295 | 3 | 0 | 3 |
| EIF1B | PCBD2 | 0.711872 | 3 | 0 | 3 |
| EIF1B | POLR2G | 0.711861 | 3 | 0 | 3 |
| EIF1B | IQSEC1 | 0.711043 | 3 | 0 | 3 |
| EIF1B | EIF3M | 0.708659 | 4 | 0 | 4 |
| EIF1B | PCDH7 | 0.707478 | 4 | 0 | 3 |
| EIF1B | ZNF649 | 0.705606 | 3 | 0 | 3 |
| EIF1B | RRP36 | 0.704643 | 3 | 0 | 3 |
| EIF1B | TTBK2 | 0.704399 | 3 | 0 | 3 |
| EIF1B | TIPARP | 0.702793 | 3 | 0 | 3 |
For details and further investigation, click here
