| Full name: ribosomal protein L38 | Alias Symbol: L38 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 6169 | HGNC ID: HGNC:10349 | Ensembl Gene: ENSG00000172809 | OMIM ID: 604182 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPL38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL38 | 6169 | 202029_x_at | 0.0127 | 0.9655 | |
| GSE20347 | RPL38 | 6169 | 202029_x_at | 0.0283 | 0.8010 | |
| GSE23400 | RPL38 | 6169 | 202029_x_at | 0.0969 | 0.0727 | |
| GSE26886 | RPL38 | 6169 | 202029_x_at | 0.1887 | 0.2375 | |
| GSE29001 | RPL38 | 6169 | 202029_x_at | 0.0024 | 0.9877 | |
| GSE38129 | RPL38 | 6169 | 202029_x_at | 0.0706 | 0.3193 | |
| GSE45670 | RPL38 | 6169 | 202029_x_at | -0.0447 | 0.7320 | |
| GSE53622 | RPL38 | 6169 | 138647 | -0.0788 | 0.1574 | |
| GSE53624 | RPL38 | 6169 | 138647 | 0.3853 | 0.0000 | |
| GSE63941 | RPL38 | 6169 | 202029_x_at | 0.7480 | 0.0006 | |
| GSE77861 | RPL38 | 6169 | 202029_x_at | 0.2058 | 0.2408 | |
| GSE97050 | RPL38 | 6169 | A_23_P95879 | -0.1943 | 0.3903 | |
| SRP007169 | RPL38 | 6169 | RNAseq | -0.4379 | 0.1727 | |
| SRP008496 | RPL38 | 6169 | RNAseq | -0.4558 | 0.0166 | |
| SRP064894 | RPL38 | 6169 | RNAseq | 0.2510 | 0.5363 | |
| SRP133303 | RPL38 | 6169 | RNAseq | -0.0273 | 0.8744 | |
| SRP159526 | RPL38 | 6169 | RNAseq | -0.0846 | 0.5424 | |
| SRP193095 | RPL38 | 6169 | RNAseq | -0.6090 | 0.0001 | |
| SRP219564 | RPL38 | 6169 | RNAseq | 0.3074 | 0.4993 | |
| TCGA | RPL38 | 6169 | RNAseq | 0.1199 | 0.0236 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPL38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL38 | 6169 | 3 | 2 | 25 | |
| GSE20123 | RPL38 | 6169 | 3 | 2 | 25 | |
| GSE43470 | RPL38 | 6169 | 6 | 3 | 34 | |
| GSE46452 | RPL38 | 6169 | 33 | 0 | 26 | |
| GSE47630 | RPL38 | 6169 | 8 | 1 | 31 | |
| GSE54993 | RPL38 | 6169 | 2 | 5 | 63 | |
| GSE54994 | RPL38 | 6169 | 10 | 4 | 39 | |
| GSE60625 | RPL38 | 6169 | 6 | 0 | 5 | |
| GSE74703 | RPL38 | 6169 | 6 | 1 | 29 | |
| GSE74704 | RPL38 | 6169 | 3 | 1 | 16 | |
| TCGA | RPL38 | 6169 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 29; Total Number of normals: 347.
Somatic mutations of RPL38:
Generating mutation plots.
Highly correlated genes for RPL38:
Showing top 20/341 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL38 | MYLIP | 0.785748 | 3 | 0 | 3 |
| RPL38 | SLC39A3 | 0.745963 | 3 | 0 | 3 |
| RPL38 | SSBP4 | 0.736825 | 3 | 0 | 3 |
| RPL38 | LENG8 | 0.730524 | 3 | 0 | 3 |
| RPL38 | INO80E | 0.724209 | 3 | 0 | 3 |
| RPL38 | MRPL38 | 0.724053 | 4 | 0 | 3 |
| RPL38 | PCGF2 | 0.719356 | 3 | 0 | 3 |
| RPL38 | MAPRE3 | 0.697428 | 3 | 0 | 3 |
| RPL38 | VRK3 | 0.692763 | 3 | 0 | 3 |
| RPL38 | CAMTA1 | 0.688547 | 3 | 0 | 3 |
| RPL38 | NR1H2 | 0.68648 | 4 | 0 | 3 |
| RPL38 | RPL13A | 0.685922 | 3 | 0 | 3 |
| RPL38 | SNAI3 | 0.681176 | 3 | 0 | 3 |
| RPL38 | AP1M2 | 0.680415 | 4 | 0 | 4 |
| RPL38 | RNPS1 | 0.67882 | 4 | 0 | 3 |
| RPL38 | TP53I13 | 0.678727 | 3 | 0 | 3 |
| RPL38 | GRASP | 0.676574 | 3 | 0 | 3 |
| RPL38 | INPP5K | 0.675545 | 3 | 0 | 3 |
| RPL38 | HSPA5 | 0.674503 | 3 | 0 | 3 |
| RPL38 | ANKZF1 | 0.673179 | 3 | 0 | 3 |
For details and further investigation, click here
