| Full name: phosphatidylinositol transfer protein cytoplasmic 1 | Alias Symbol: RDGBB1|RDGBB|RDGB-BETA | ||
| Type: protein-coding gene | Cytoband: 17q24.3 | ||
| Entrez ID: 26207 | HGNC ID: HGNC:21045 | Ensembl Gene: ENSG00000154217 | OMIM ID: 605134 |
| Drug and gene relationship at DGIdb | |||
Expression of PITPNC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PITPNC1 | 26207 | 219155_at | -0.4435 | 0.2903 | |
| GSE20347 | PITPNC1 | 26207 | 219155_at | -0.1350 | 0.5034 | |
| GSE23400 | PITPNC1 | 26207 | 219155_at | -0.0525 | 0.3648 | |
| GSE26886 | PITPNC1 | 26207 | 219155_at | 1.1964 | 0.0013 | |
| GSE29001 | PITPNC1 | 26207 | 219155_at | 0.1399 | 0.7644 | |
| GSE38129 | PITPNC1 | 26207 | 219155_at | -0.3062 | 0.0795 | |
| GSE45670 | PITPNC1 | 26207 | 219155_at | 0.3868 | 0.1460 | |
| GSE53622 | PITPNC1 | 26207 | 11510 | -0.3000 | 0.0137 | |
| GSE53624 | PITPNC1 | 26207 | 18758 | -0.1366 | 0.0869 | |
| GSE63941 | PITPNC1 | 26207 | 219155_at | -0.1424 | 0.8076 | |
| GSE77861 | PITPNC1 | 26207 | 1568949_at | -0.0660 | 0.5943 | |
| GSE97050 | PITPNC1 | 26207 | A_33_P3222341 | 0.2055 | 0.5017 | |
| SRP007169 | PITPNC1 | 26207 | RNAseq | -0.0807 | 0.8523 | |
| SRP008496 | PITPNC1 | 26207 | RNAseq | -0.2654 | 0.3740 | |
| SRP064894 | PITPNC1 | 26207 | RNAseq | 0.2703 | 0.2780 | |
| SRP133303 | PITPNC1 | 26207 | RNAseq | -0.2809 | 0.1920 | |
| SRP159526 | PITPNC1 | 26207 | RNAseq | -0.5802 | 0.0457 | |
| SRP193095 | PITPNC1 | 26207 | RNAseq | 0.2684 | 0.1175 | |
| SRP219564 | PITPNC1 | 26207 | RNAseq | -0.1672 | 0.6737 | |
| TCGA | PITPNC1 | 26207 | RNAseq | -0.3317 | 0.0005 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PITPNC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PITPNC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PITPNC1 | 26207 | 3 | 2 | 25 | |
| GSE20123 | PITPNC1 | 26207 | 3 | 2 | 25 | |
| GSE43470 | PITPNC1 | 26207 | 5 | 0 | 38 | |
| GSE46452 | PITPNC1 | 26207 | 31 | 1 | 27 | |
| GSE47630 | PITPNC1 | 26207 | 7 | 1 | 32 | |
| GSE54993 | PITPNC1 | 26207 | 2 | 5 | 63 | |
| GSE54994 | PITPNC1 | 26207 | 9 | 4 | 40 | |
| GSE60625 | PITPNC1 | 26207 | 4 | 2 | 5 | |
| GSE74703 | PITPNC1 | 26207 | 5 | 0 | 31 | |
| GSE74704 | PITPNC1 | 26207 | 3 | 1 | 16 | |
| TCGA | PITPNC1 | 26207 | 28 | 8 | 60 |
Total number of gains: 100; Total number of losses: 26; Total Number of normals: 362.
Somatic mutations of PITPNC1:
Generating mutation plots.
Highly correlated genes for PITPNC1:
Showing top 20/102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PITPNC1 | LMO1 | 0.805486 | 3 | 0 | 3 |
| PITPNC1 | HIPK3 | 0.75289 | 3 | 0 | 3 |
| PITPNC1 | PCGF2 | 0.751045 | 3 | 0 | 3 |
| PITPNC1 | APOBR | 0.742096 | 3 | 0 | 3 |
| PITPNC1 | VTI1B | 0.73597 | 3 | 0 | 3 |
| PITPNC1 | BCL6 | 0.713078 | 3 | 0 | 3 |
| PITPNC1 | MTMR11 | 0.711532 | 3 | 0 | 3 |
| PITPNC1 | SERPINF2 | 0.701676 | 3 | 0 | 3 |
| PITPNC1 | BEGAIN | 0.700095 | 3 | 0 | 3 |
| PITPNC1 | HEXB | 0.696176 | 3 | 0 | 3 |
| PITPNC1 | SPIRE1 | 0.693905 | 3 | 0 | 3 |
| PITPNC1 | IFI27L2 | 0.69149 | 3 | 0 | 3 |
| PITPNC1 | ANGPTL4 | 0.689259 | 3 | 0 | 3 |
| PITPNC1 | PFKP | 0.688976 | 3 | 0 | 3 |
| PITPNC1 | SLC6A6 | 0.68233 | 3 | 0 | 3 |
| PITPNC1 | A1BG | 0.679977 | 3 | 0 | 3 |
| PITPNC1 | C11orf96 | 0.67916 | 3 | 0 | 3 |
| PITPNC1 | C9orf47 | 0.677965 | 3 | 0 | 3 |
| PITPNC1 | ANG | 0.67741 | 4 | 0 | 3 |
| PITPNC1 | GPR183 | 0.67692 | 3 | 0 | 3 |
For details and further investigation, click here
