| Full name: phosphatidylcholine transfer protein | Alias Symbol: STARD2 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 58488 | HGNC ID: HGNC:8752 | Ensembl Gene: ENSG00000141179 | OMIM ID: 606055 |
| Drug and gene relationship at DGIdb | |||
Expression of PCTP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCTP | 58488 | 218676_s_at | 0.1376 | 0.8551 | |
| GSE20347 | PCTP | 58488 | 218676_s_at | -0.6207 | 0.0103 | |
| GSE23400 | PCTP | 58488 | 218676_s_at | -0.0041 | 0.9536 | |
| GSE26886 | PCTP | 58488 | 218676_s_at | -0.9305 | 0.0129 | |
| GSE29001 | PCTP | 58488 | 218676_s_at | -0.3724 | 0.3347 | |
| GSE38129 | PCTP | 58488 | 218676_s_at | -0.3659 | 0.0792 | |
| GSE45670 | PCTP | 58488 | 218676_s_at | -0.2274 | 0.4364 | |
| GSE53622 | PCTP | 58488 | 90321 | -0.4210 | 0.0000 | |
| GSE53624 | PCTP | 58488 | 90321 | -0.4724 | 0.0000 | |
| GSE63941 | PCTP | 58488 | 218676_s_at | 0.2005 | 0.7882 | |
| GSE77861 | PCTP | 58488 | 218676_s_at | -0.2763 | 0.4671 | |
| GSE97050 | PCTP | 58488 | A_23_P4041 | 0.1212 | 0.6286 | |
| SRP007169 | PCTP | 58488 | RNAseq | -1.4838 | 0.0065 | |
| SRP008496 | PCTP | 58488 | RNAseq | -0.8305 | 0.0256 | |
| SRP064894 | PCTP | 58488 | RNAseq | 0.3759 | 0.0506 | |
| SRP133303 | PCTP | 58488 | RNAseq | 0.3760 | 0.1795 | |
| SRP159526 | PCTP | 58488 | RNAseq | 0.3543 | 0.3930 | |
| SRP193095 | PCTP | 58488 | RNAseq | -0.4415 | 0.0076 | |
| SRP219564 | PCTP | 58488 | RNAseq | 0.0164 | 0.9672 | |
| TCGA | PCTP | 58488 | RNAseq | -0.1668 | 0.0821 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PCTP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCTP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCTP | 58488 | 4 | 1 | 25 | |
| GSE20123 | PCTP | 58488 | 4 | 1 | 25 | |
| GSE43470 | PCTP | 58488 | 2 | 1 | 40 | |
| GSE46452 | PCTP | 58488 | 32 | 0 | 27 | |
| GSE47630 | PCTP | 58488 | 7 | 1 | 32 | |
| GSE54993 | PCTP | 58488 | 2 | 4 | 64 | |
| GSE54994 | PCTP | 58488 | 9 | 5 | 39 | |
| GSE60625 | PCTP | 58488 | 4 | 0 | 7 | |
| GSE74703 | PCTP | 58488 | 2 | 1 | 33 | |
| GSE74704 | PCTP | 58488 | 3 | 1 | 16 | |
| TCGA | PCTP | 58488 | 26 | 7 | 63 |
Total number of gains: 95; Total number of losses: 22; Total Number of normals: 371.
Somatic mutations of PCTP:
Generating mutation plots.
Highly correlated genes for PCTP:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCTP | ZNF597 | 0.810031 | 3 | 0 | 3 |
| PCTP | CREBBP | 0.787414 | 3 | 0 | 3 |
| PCTP | ZNF564 | 0.771991 | 3 | 0 | 3 |
| PCTP | WDFY1 | 0.753273 | 4 | 0 | 4 |
| PCTP | TM2D2 | 0.747656 | 3 | 0 | 3 |
| PCTP | FN3KRP | 0.745144 | 3 | 0 | 3 |
| PCTP | PUS7L | 0.736416 | 3 | 0 | 3 |
| PCTP | MKKS | 0.729661 | 3 | 0 | 3 |
| PCTP | ACVR1B | 0.727029 | 3 | 0 | 3 |
| PCTP | FAM171B | 0.725837 | 3 | 0 | 3 |
| PCTP | SPCS2 | 0.724268 | 3 | 0 | 3 |
| PCTP | JAG1 | 0.720226 | 3 | 0 | 3 |
| PCTP | CMTM6 | 0.719359 | 5 | 0 | 5 |
| PCTP | EIF3I | 0.718142 | 3 | 0 | 3 |
| PCTP | STRN | 0.708325 | 3 | 0 | 3 |
| PCTP | CCDC117 | 0.707266 | 3 | 0 | 3 |
| PCTP | ITPRIPL2 | 0.700236 | 3 | 0 | 3 |
| PCTP | LRRC41 | 0.698748 | 5 | 0 | 5 |
| PCTP | FRAT1 | 0.697833 | 4 | 0 | 4 |
| PCTP | ZCCHC8 | 0.695914 | 3 | 0 | 3 |
For details and further investigation, click here
