| Full name: striatin | Alias Symbol: PPP2R6A|STRN1 | ||
| Type: protein-coding gene | Cytoband: 2p22.2 | ||
| Entrez ID: 6801 | HGNC ID: HGNC:11424 | Ensembl Gene: ENSG00000115808 | OMIM ID: 614765 |
| Drug and gene relationship at DGIdb | |||
Expression of STRN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRN | 6801 | 230734_x_at | -0.7140 | 0.4656 | |
| GSE20347 | STRN | 6801 | 215287_at | -0.3980 | 0.1540 | |
| GSE23400 | STRN | 6801 | 205520_at | -0.3497 | 0.0000 | |
| GSE26886 | STRN | 6801 | 230734_x_at | -1.4566 | 0.0000 | |
| GSE29001 | STRN | 6801 | 215287_at | -0.3013 | 0.4045 | |
| GSE38129 | STRN | 6801 | 215287_at | -0.2638 | 0.2609 | |
| GSE45670 | STRN | 6801 | 230734_x_at | -0.4062 | 0.0776 | |
| GSE53622 | STRN | 6801 | 96648 | -0.7743 | 0.0000 | |
| GSE53624 | STRN | 6801 | 96648 | -0.9049 | 0.0000 | |
| GSE63941 | STRN | 6801 | 230734_x_at | -0.3058 | 0.5184 | |
| GSE77861 | STRN | 6801 | 230734_x_at | -0.9900 | 0.0341 | |
| GSE97050 | STRN | 6801 | A_23_P165521 | 0.0388 | 0.9381 | |
| SRP007169 | STRN | 6801 | RNAseq | -2.1395 | 0.0000 | |
| SRP008496 | STRN | 6801 | RNAseq | -1.9749 | 0.0000 | |
| SRP064894 | STRN | 6801 | RNAseq | -1.7321 | 0.0000 | |
| SRP133303 | STRN | 6801 | RNAseq | -0.8736 | 0.0000 | |
| SRP159526 | STRN | 6801 | RNAseq | -1.1067 | 0.0000 | |
| SRP193095 | STRN | 6801 | RNAseq | -1.0723 | 0.0000 | |
| SRP219564 | STRN | 6801 | RNAseq | -1.6967 | 0.0037 | |
| TCGA | STRN | 6801 | RNAseq | 0.0407 | 0.5466 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by STRN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRN | 6801 | 10 | 1 | 19 | |
| GSE20123 | STRN | 6801 | 9 | 1 | 20 | |
| GSE43470 | STRN | 6801 | 3 | 0 | 40 | |
| GSE46452 | STRN | 6801 | 1 | 4 | 54 | |
| GSE47630 | STRN | 6801 | 7 | 0 | 33 | |
| GSE54993 | STRN | 6801 | 0 | 5 | 65 | |
| GSE54994 | STRN | 6801 | 10 | 0 | 43 | |
| GSE60625 | STRN | 6801 | 0 | 3 | 8 | |
| GSE74703 | STRN | 6801 | 3 | 0 | 33 | |
| GSE74704 | STRN | 6801 | 9 | 1 | 10 | |
| TCGA | STRN | 6801 | 35 | 2 | 59 |
Total number of gains: 87; Total number of losses: 17; Total Number of normals: 384.
Somatic mutations of STRN:
Generating mutation plots.
Highly correlated genes for STRN:
Showing top 20/1245 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRN | MPZL3 | 0.840675 | 7 | 0 | 7 |
| STRN | CNFN | 0.800662 | 6 | 0 | 6 |
| STRN | PCBP1-AS1 | 0.798815 | 3 | 0 | 3 |
| STRN | EPG5 | 0.792544 | 4 | 0 | 4 |
| STRN | DDI2 | 0.791698 | 3 | 0 | 3 |
| STRN | A2ML1 | 0.788622 | 6 | 0 | 6 |
| STRN | CCNYL1 | 0.786969 | 5 | 0 | 5 |
| STRN | CYSRT1 | 0.785433 | 6 | 0 | 6 |
| STRN | ARHGAP27 | 0.783715 | 7 | 0 | 7 |
| STRN | GRPEL2 | 0.779829 | 7 | 0 | 7 |
| STRN | MUC15 | 0.76698 | 6 | 0 | 6 |
| STRN | NUAK2 | 0.765418 | 3 | 0 | 3 |
| STRN | ITCH | 0.764946 | 7 | 0 | 7 |
| STRN | GRHL3 | 0.764109 | 6 | 0 | 6 |
| STRN | RAB10 | 0.761529 | 7 | 0 | 6 |
| STRN | ZNF770 | 0.759818 | 7 | 0 | 7 |
| STRN | ATG9B | 0.752572 | 7 | 0 | 7 |
| STRN | PRDM1 | 0.746819 | 8 | 0 | 7 |
| STRN | C15orf62 | 0.746139 | 7 | 0 | 7 |
| STRN | SH3PXD2A-AS1 | 0.743449 | 4 | 0 | 4 |
For details and further investigation, click here
