CMTM6

 

Full name: CKLF like MARVEL transmembrane domain containing 6 Alias Symbol: FLJ20396
Type: protein-coding gene Cytoband: 3p22.3
Entrez ID: 54918 HGNC ID: HGNC:19177 Ensembl Gene: ENSG00000091317 OMIM ID: 607889
Drug and gene relationship at DGIdb

 

Expression of CMTM6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CMTM6 54918 217947_at 0.2578 0.5256
GSE20347 CMTM6 54918 217947_at -0.2961 0.0190
GSE23400 CMTM6 54918 217947_at 0.0109 0.8955
GSE26886 CMTM6 54918 217947_at -0.5144 0.0120
GSE29001 CMTM6 54918 217947_at -0.2278 0.4931
GSE38129 CMTM6 54918 217947_at -0.1255 0.4086
GSE45670 CMTM6 54918 217947_at 0.2300 0.0405
GSE53622 CMTM6 54918 78223 -0.1517 0.0681
GSE53624 CMTM6 54918 78223 -0.3496 0.0008
GSE63941 CMTM6 54918 217947_at -0.6167 0.2285
GSE77861 CMTM6 54918 217947_at -0.1485 0.4928
GSE97050 CMTM6 54918 A_24_P97526 0.4604 0.3717
SRP007169 CMTM6 54918 RNAseq -0.1457 0.6851
SRP008496 CMTM6 54918 RNAseq -0.2502 0.1661
SRP064894 CMTM6 54918 RNAseq 0.0343 0.8592
SRP133303 CMTM6 54918 RNAseq 0.1638 0.2207
SRP159526 CMTM6 54918 RNAseq -0.2827 0.3466
SRP193095 CMTM6 54918 RNAseq -0.6619 0.0000
SRP219564 CMTM6 54918 RNAseq -0.4151 0.2310
TCGA CMTM6 54918 RNAseq 0.0706 0.1283

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CMTM6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CMTM6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CMTM6 54918 0 18 12
GSE20123 CMTM6 54918 0 18 12
GSE43470 CMTM6 54918 1 20 22
GSE46452 CMTM6 54918 2 17 40
GSE47630 CMTM6 54918 1 25 14
GSE54993 CMTM6 54918 6 3 61
GSE54994 CMTM6 54918 1 32 20
GSE60625 CMTM6 54918 5 0 6
GSE74703 CMTM6 54918 1 17 18
GSE74704 CMTM6 54918 0 12 8
TCGA CMTM6 54918 2 69 25

Total number of gains: 19; Total number of losses: 231; Total Number of normals: 238.  


 

Somatic mutations of CMTM6:

 

Generating mutation plots.

 

Highly correlated genes for CMTM6:

 

Showing top 20/654 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CMTM6UNC5CL0.83038303
CMTM6NDUFS10.817315303
CMTM6PARG0.802054303
CMTM6RRP360.784091303
CMTM6POLB0.781547404
CMTM6PGK10.779287303
CMTM6CNOT100.777135303
CMTM6LCMT10.777096303
CMTM6PPIL10.767575404
CMTM6ZBTB90.747505303
CMTM6RBBP60.742226303
CMTM6SMAD20.741189303
CMTM6TM2D20.73999303
CMTM6FAM200A0.734377303
CMTM6SPCS20.733681404
CMTM6ARPC1A0.73025403
CMTM6ORC40.728782303
CMTM6TRAPPC6B0.727442303
CMTM6ARPC40.724465303
CMTM6NXT20.723536505

For details and further investigation, click here