| Full name: prenylcysteine oxidase 1 | Alias Symbol: KIAA0908|PCL1 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 51449 | HGNC ID: HGNC:20588 | Ensembl Gene: ENSG00000116005 | OMIM ID: 610995 |
| Drug and gene relationship at DGIdb | |||
Expression of PCYOX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCYOX1 | 51449 | 225274_at | -0.7013 | 0.2882 | |
| GSE20347 | PCYOX1 | 51449 | 203803_at | -1.2255 | 0.0001 | |
| GSE23400 | PCYOX1 | 51449 | 203803_at | -0.3101 | 0.0002 | |
| GSE26886 | PCYOX1 | 51449 | 225274_at | -0.9538 | 0.0000 | |
| GSE29001 | PCYOX1 | 51449 | 203803_at | -1.0821 | 0.1091 | |
| GSE38129 | PCYOX1 | 51449 | 203803_at | -0.9645 | 0.0000 | |
| GSE45670 | PCYOX1 | 51449 | 225274_at | -0.4893 | 0.0035 | |
| GSE53622 | PCYOX1 | 51449 | 69282 | -0.6611 | 0.0000 | |
| GSE53624 | PCYOX1 | 51449 | 69282 | -0.7862 | 0.0000 | |
| GSE63941 | PCYOX1 | 51449 | 225274_at | -1.9509 | 0.0004 | |
| GSE77861 | PCYOX1 | 51449 | 225274_at | -0.5059 | 0.0046 | |
| GSE97050 | PCYOX1 | 51449 | A_32_P180958 | -1.0323 | 0.0826 | |
| SRP007169 | PCYOX1 | 51449 | RNAseq | -0.3264 | 0.3582 | |
| SRP008496 | PCYOX1 | 51449 | RNAseq | -0.2183 | 0.2085 | |
| SRP064894 | PCYOX1 | 51449 | RNAseq | -0.6613 | 0.0002 | |
| SRP133303 | PCYOX1 | 51449 | RNAseq | -0.3721 | 0.0359 | |
| SRP159526 | PCYOX1 | 51449 | RNAseq | -0.3286 | 0.1590 | |
| SRP193095 | PCYOX1 | 51449 | RNAseq | -0.5241 | 0.0001 | |
| SRP219564 | PCYOX1 | 51449 | RNAseq | -0.7766 | 0.0044 | |
| TCGA | PCYOX1 | 51449 | RNAseq | -0.0911 | 0.0352 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PCYOX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCYOX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCYOX1 | 51449 | 11 | 1 | 18 | |
| GSE20123 | PCYOX1 | 51449 | 11 | 0 | 19 | |
| GSE43470 | PCYOX1 | 51449 | 3 | 0 | 40 | |
| GSE46452 | PCYOX1 | 51449 | 2 | 3 | 54 | |
| GSE47630 | PCYOX1 | 51449 | 7 | 0 | 33 | |
| GSE54993 | PCYOX1 | 51449 | 0 | 6 | 64 | |
| GSE54994 | PCYOX1 | 51449 | 11 | 0 | 42 | |
| GSE60625 | PCYOX1 | 51449 | 0 | 3 | 8 | |
| GSE74703 | PCYOX1 | 51449 | 3 | 0 | 33 | |
| GSE74704 | PCYOX1 | 51449 | 9 | 1 | 10 | |
| TCGA | PCYOX1 | 51449 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 16; Total Number of normals: 379.
Somatic mutations of PCYOX1:
Generating mutation plots.
Highly correlated genes for PCYOX1:
Showing top 20/1313 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCYOX1 | VDAC3 | 0.75729 | 3 | 0 | 3 |
| PCYOX1 | RBM20 | 0.745988 | 4 | 0 | 4 |
| PCYOX1 | LRRK2 | 0.735644 | 7 | 0 | 7 |
| PCYOX1 | UGP2 | 0.730623 | 9 | 0 | 8 |
| PCYOX1 | SPAG17 | 0.727149 | 4 | 0 | 4 |
| PCYOX1 | ZNF382 | 0.722176 | 3 | 0 | 3 |
| PCYOX1 | ZNF585A | 0.72196 | 3 | 0 | 3 |
| PCYOX1 | WDR73 | 0.714945 | 3 | 0 | 3 |
| PCYOX1 | ZNF416 | 0.714279 | 4 | 0 | 4 |
| PCYOX1 | TRIM6 | 0.710964 | 7 | 0 | 6 |
| PCYOX1 | SUMF1 | 0.707595 | 4 | 0 | 4 |
| PCYOX1 | ACADM | 0.706107 | 11 | 0 | 10 |
| PCYOX1 | SH3D19 | 0.702468 | 8 | 0 | 8 |
| PCYOX1 | RAB5B | 0.70091 | 8 | 0 | 8 |
| PCYOX1 | CTTNBP2 | 0.699184 | 7 | 0 | 7 |
| PCYOX1 | SH3BGRL2 | 0.697455 | 7 | 0 | 7 |
| PCYOX1 | TUNAR | 0.69721 | 3 | 0 | 3 |
| PCYOX1 | USP46 | 0.695669 | 9 | 0 | 8 |
| PCYOX1 | CPPED1 | 0.693892 | 11 | 0 | 10 |
| PCYOX1 | CGNL1 | 0.692667 | 6 | 0 | 6 |
For details and further investigation, click here
