| Full name: WD repeat domain 73 | Alias Symbol: FLJ14888|HSPC264 | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 84942 | HGNC ID: HGNC:25928 | Ensembl Gene: ENSG00000177082 | OMIM ID: 616144 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of WDR73:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR73 | 84942 | 213031_s_at | -0.0476 | 0.9082 | |
| GSE20347 | WDR73 | 84942 | 213031_s_at | 0.0656 | 0.5326 | |
| GSE23400 | WDR73 | 84942 | 213031_s_at | -0.0396 | 0.3009 | |
| GSE26886 | WDR73 | 84942 | 213031_s_at | -0.3593 | 0.0121 | |
| GSE29001 | WDR73 | 84942 | 213031_s_at | 0.0071 | 0.9747 | |
| GSE38129 | WDR73 | 84942 | 213031_s_at | 0.1718 | 0.0692 | |
| GSE45670 | WDR73 | 84942 | 213031_s_at | 0.0480 | 0.6387 | |
| GSE53622 | WDR73 | 84942 | 67623 | 0.1602 | 0.0114 | |
| GSE53624 | WDR73 | 84942 | 67623 | 0.1926 | 0.0035 | |
| GSE63941 | WDR73 | 84942 | 213031_s_at | 0.4739 | 0.2838 | |
| GSE77861 | WDR73 | 84942 | 213031_s_at | 0.1471 | 0.4897 | |
| GSE97050 | WDR73 | 84942 | A_24_P230721 | -0.2145 | 0.2641 | |
| SRP007169 | WDR73 | 84942 | RNAseq | 0.0856 | 0.8400 | |
| SRP008496 | WDR73 | 84942 | RNAseq | 0.0670 | 0.8201 | |
| SRP064894 | WDR73 | 84942 | RNAseq | -0.0891 | 0.4035 | |
| SRP133303 | WDR73 | 84942 | RNAseq | -0.0588 | 0.5628 | |
| SRP159526 | WDR73 | 84942 | RNAseq | 0.0934 | 0.7166 | |
| SRP193095 | WDR73 | 84942 | RNAseq | 0.0809 | 0.2547 | |
| SRP219564 | WDR73 | 84942 | RNAseq | -0.1870 | 0.4352 | |
| TCGA | WDR73 | 84942 | RNAseq | -0.0195 | 0.7373 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR73 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR73:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR73 | 84942 | 8 | 0 | 22 | |
| GSE20123 | WDR73 | 84942 | 8 | 0 | 22 | |
| GSE43470 | WDR73 | 84942 | 4 | 4 | 35 | |
| GSE46452 | WDR73 | 84942 | 3 | 7 | 49 | |
| GSE47630 | WDR73 | 84942 | 8 | 10 | 22 | |
| GSE54993 | WDR73 | 84942 | 5 | 6 | 59 | |
| GSE54994 | WDR73 | 84942 | 6 | 6 | 41 | |
| GSE60625 | WDR73 | 84942 | 4 | 0 | 7 | |
| GSE74703 | WDR73 | 84942 | 4 | 2 | 30 | |
| GSE74704 | WDR73 | 84942 | 4 | 0 | 16 | |
| TCGA | WDR73 | 84942 | 16 | 13 | 67 |
Total number of gains: 70; Total number of losses: 48; Total Number of normals: 370.
Somatic mutations of WDR73:
Generating mutation plots.
Highly correlated genes for WDR73:
Showing top 20/167 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR73 | LONRF1 | 0.766062 | 3 | 0 | 3 |
| WDR73 | NDUFA10 | 0.763074 | 3 | 0 | 3 |
| WDR73 | SEC63 | 0.758113 | 3 | 0 | 3 |
| WDR73 | EIF2B4 | 0.749723 | 3 | 0 | 3 |
| WDR73 | AP4E1 | 0.718664 | 3 | 0 | 3 |
| WDR73 | TMED2 | 0.71788 | 3 | 0 | 3 |
| WDR73 | TTC23 | 0.71521 | 3 | 0 | 3 |
| WDR73 | PCYOX1 | 0.714945 | 3 | 0 | 3 |
| WDR73 | GPSM2 | 0.712603 | 3 | 0 | 3 |
| WDR73 | SLTM | 0.712084 | 3 | 0 | 3 |
| WDR73 | TRIP4 | 0.706108 | 3 | 0 | 3 |
| WDR73 | RRN3 | 0.702518 | 3 | 0 | 3 |
| WDR73 | MTO1 | 0.700603 | 3 | 0 | 3 |
| WDR73 | VPS29 | 0.699136 | 3 | 0 | 3 |
| WDR73 | UBA3 | 0.693625 | 3 | 0 | 3 |
| WDR73 | PITPNM3 | 0.679539 | 3 | 0 | 3 |
| WDR73 | ZNF566 | 0.678248 | 3 | 0 | 3 |
| WDR73 | MBTPS2 | 0.675167 | 3 | 0 | 3 |
| WDR73 | ACSL3 | 0.674716 | 3 | 0 | 3 |
| WDR73 | NMNAT1 | 0.673538 | 3 | 0 | 3 |
For details and further investigation, click here
