| Full name: programmed cell death 2 | Alias Symbol: ZMYND7|RP8 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 5134 | HGNC ID: HGNC:8762 | Ensembl Gene: ENSG00000071994 | OMIM ID: 600866 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PDCD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCD2 | 5134 | 204025_s_at | -0.1682 | 0.7379 | |
| GSE20347 | PDCD2 | 5134 | 213581_at | 0.2088 | 0.4407 | |
| GSE23400 | PDCD2 | 5134 | 213581_at | 0.4899 | 0.0000 | |
| GSE26886 | PDCD2 | 5134 | 213581_at | 0.9815 | 0.0006 | |
| GSE29001 | PDCD2 | 5134 | 213581_at | 0.3108 | 0.3955 | |
| GSE38129 | PDCD2 | 5134 | 213581_at | 0.3490 | 0.0395 | |
| GSE45670 | PDCD2 | 5134 | 204025_s_at | 0.2445 | 0.0906 | |
| GSE53622 | PDCD2 | 5134 | 116202 | 0.0918 | 0.1648 | |
| GSE53624 | PDCD2 | 5134 | 116202 | 0.1157 | 0.0471 | |
| GSE63941 | PDCD2 | 5134 | 204025_s_at | -0.0654 | 0.9067 | |
| GSE77861 | PDCD2 | 5134 | 204025_s_at | -0.0591 | 0.8542 | |
| GSE97050 | PDCD2 | 5134 | A_23_P145146 | 0.2083 | 0.4225 | |
| SRP007169 | PDCD2 | 5134 | RNAseq | -0.3056 | 0.3941 | |
| SRP008496 | PDCD2 | 5134 | RNAseq | -0.3553 | 0.0955 | |
| SRP064894 | PDCD2 | 5134 | RNAseq | -0.0784 | 0.5029 | |
| SRP133303 | PDCD2 | 5134 | RNAseq | 0.2396 | 0.1793 | |
| SRP159526 | PDCD2 | 5134 | RNAseq | -0.1953 | 0.5541 | |
| SRP193095 | PDCD2 | 5134 | RNAseq | -0.3195 | 0.0035 | |
| SRP219564 | PDCD2 | 5134 | RNAseq | -0.2577 | 0.1772 | |
| TCGA | PDCD2 | 5134 | RNAseq | 0.0502 | 0.3665 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDCD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCD2 | 5134 | 4 | 6 | 20 | |
| GSE20123 | PDCD2 | 5134 | 4 | 6 | 20 | |
| GSE43470 | PDCD2 | 5134 | 2 | 0 | 41 | |
| GSE46452 | PDCD2 | 5134 | 3 | 10 | 46 | |
| GSE47630 | PDCD2 | 5134 | 7 | 7 | 26 | |
| GSE54993 | PDCD2 | 5134 | 4 | 3 | 63 | |
| GSE54994 | PDCD2 | 5134 | 9 | 9 | 35 | |
| GSE60625 | PDCD2 | 5134 | 1 | 1 | 9 | |
| GSE74703 | PDCD2 | 5134 | 2 | 0 | 34 | |
| GSE74704 | PDCD2 | 5134 | 2 | 3 | 15 | |
| TCGA | PDCD2 | 5134 | 14 | 20 | 62 |
Total number of gains: 52; Total number of losses: 65; Total Number of normals: 371.
Somatic mutations of PDCD2:
Generating mutation plots.
Highly correlated genes for PDCD2:
Showing top 20/333 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCD2 | HORMAD1 | 0.732196 | 3 | 0 | 3 |
| PDCD2 | NAA20 | 0.674184 | 3 | 0 | 3 |
| PDCD2 | EEF1E1 | 0.659003 | 7 | 0 | 7 |
| PDCD2 | GTPBP8 | 0.653056 | 3 | 0 | 3 |
| PDCD2 | PFAS | 0.651822 | 7 | 0 | 6 |
| PDCD2 | RPL22L1 | 0.650834 | 3 | 0 | 3 |
| PDCD2 | UTP14A | 0.647581 | 6 | 0 | 6 |
| PDCD2 | ACYP1 | 0.645077 | 6 | 0 | 4 |
| PDCD2 | ORC2 | 0.643717 | 4 | 0 | 4 |
| PDCD2 | SLC30A7 | 0.64287 | 3 | 0 | 3 |
| PDCD2 | TRAF3IP3 | 0.6418 | 3 | 0 | 3 |
| PDCD2 | NUP43 | 0.640833 | 8 | 0 | 8 |
| PDCD2 | GEMIN5 | 0.633595 | 3 | 0 | 3 |
| PDCD2 | MYBL1 | 0.632841 | 3 | 0 | 3 |
| PDCD2 | UBLCP1 | 0.631771 | 3 | 0 | 3 |
| PDCD2 | PRPF8 | 0.631045 | 4 | 0 | 4 |
| PDCD2 | FIBP | 0.624631 | 4 | 0 | 3 |
| PDCD2 | LIG4 | 0.624316 | 3 | 0 | 3 |
| PDCD2 | ZBTB8OS | 0.619491 | 4 | 0 | 4 |
| PDCD2 | RPAIN | 0.619404 | 3 | 0 | 3 |
For details and further investigation, click here
