TRAF3IP3

 

Full name: TRAF3 interacting protein 3 Alias Symbol: T3JAM
Type: protein-coding gene Cytoband: 1q32.2
Entrez ID: 80342 HGNC ID: HGNC:30766 Ensembl Gene: ENSG00000009790 OMIM ID: 608255
Drug and gene relationship at DGIdb

 

Expression of TRAF3IP3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRAF3IP3 80342 205804_s_at 0.0887 0.9180
GSE20347 TRAF3IP3 80342 205804_s_at 0.1047 0.5055
GSE23400 TRAF3IP3 80342 213888_s_at 0.0307 0.7151
GSE26886 TRAF3IP3 80342 213888_s_at -0.7552 0.0513
GSE29001 TRAF3IP3 80342 213888_s_at 0.2863 0.5383
GSE38129 TRAF3IP3 80342 205804_s_at 0.0004 0.9983
GSE45670 TRAF3IP3 80342 213888_s_at -0.2988 0.3606
GSE53622 TRAF3IP3 80342 91594 0.0310 0.8607
GSE53624 TRAF3IP3 80342 91594 -0.4114 0.0011
GSE63941 TRAF3IP3 80342 215275_at 0.1782 0.1368
GSE77861 TRAF3IP3 80342 215275_at -0.1639 0.0827
GSE97050 TRAF3IP3 80342 A_23_P323761 1.2094 0.2296
SRP064894 TRAF3IP3 80342 RNAseq 0.1532 0.5727
SRP133303 TRAF3IP3 80342 RNAseq -0.1485 0.6635
SRP159526 TRAF3IP3 80342 RNAseq 0.2836 0.7511
SRP193095 TRAF3IP3 80342 RNAseq 0.2446 0.3872
SRP219564 TRAF3IP3 80342 RNAseq 0.3602 0.4875
TCGA TRAF3IP3 80342 RNAseq 0.2772 0.1560

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TRAF3IP3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TRAF3IP3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRAF3IP3 80342 11 0 19
GSE20123 TRAF3IP3 80342 10 0 20
GSE43470 TRAF3IP3 80342 7 0 36
GSE46452 TRAF3IP3 80342 3 1 55
GSE47630 TRAF3IP3 80342 15 0 25
GSE54993 TRAF3IP3 80342 0 6 64
GSE54994 TRAF3IP3 80342 14 0 39
GSE60625 TRAF3IP3 80342 0 0 11
GSE74703 TRAF3IP3 80342 7 0 29
GSE74704 TRAF3IP3 80342 4 0 16
TCGA TRAF3IP3 80342 44 3 49

Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.  

 

Somatic mutations of TRAF3IP3:

 

Generating mutation plots.

 

Highly correlated genes for TRAF3IP3:

 

Showing top 20/267 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRAF3IP3ZC3H12D0.785349404
TRAF3IP3TRAT10.743016807
TRAF3IP3DOCK20.720319909
TRAF3IP3NLRC30.718277706
TRAF3IP3LYZ0.711625404
TRAF3IP3CD520.70584210010
TRAF3IP3TRG-AS10.696701504
TRAF3IP3IRF80.6828261008
TRAF3IP3CYTIP0.679483907
TRAF3IP3MAST30.678797303
TRAF3IP3SV2B0.678163303
TRAF3IP3PARVG0.672215706
TRAF3IP3HLA-DMB0.67201310010
TRAF3IP3INPP5D0.6712810010
TRAF3IP3TNFSF80.668991404
TRAF3IP3CD20.6640711010
TRAF3IP3ITGB2-AS10.663734403
TRAF3IP3CD3D0.65961112010
TRAF3IP3TSTA30.659354403
TRAF3IP3P2RY80.659209503

For details and further investigation, click here