| Full name: platelet derived growth factor receptor like | Alias Symbol: PRLTS | ||
| Type: protein-coding gene | Cytoband: 8p22 | ||
| Entrez ID: 5157 | HGNC ID: HGNC:8805 | Ensembl Gene: ENSG00000104213 | OMIM ID: 604584 |
| Drug and gene relationship at DGIdb | |||
Expression of PDGFRL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDGFRL | 5157 | 205226_at | -0.0343 | 0.9838 | |
| GSE20347 | PDGFRL | 5157 | 205226_at | 0.4181 | 0.0009 | |
| GSE23400 | PDGFRL | 5157 | 205226_at | 0.2074 | 0.0193 | |
| GSE26886 | PDGFRL | 5157 | 205226_at | 1.2992 | 0.0048 | |
| GSE29001 | PDGFRL | 5157 | 205226_at | 0.5499 | 0.0130 | |
| GSE38129 | PDGFRL | 5157 | 205226_at | 0.1553 | 0.7363 | |
| GSE45670 | PDGFRL | 5157 | 205226_at | -1.0054 | 0.0463 | |
| GSE53622 | PDGFRL | 5157 | 42826 | 1.5747 | 0.0000 | |
| GSE53624 | PDGFRL | 5157 | 42826 | 2.0557 | 0.0000 | |
| GSE63941 | PDGFRL | 5157 | 205226_at | -1.9170 | 0.0122 | |
| GSE77861 | PDGFRL | 5157 | 205226_at | -0.0020 | 0.9929 | |
| GSE97050 | PDGFRL | 5157 | A_23_P60146 | 0.1900 | 0.7533 | |
| SRP007169 | PDGFRL | 5157 | RNAseq | 5.5882 | 0.0000 | |
| SRP064894 | PDGFRL | 5157 | RNAseq | 2.8728 | 0.0000 | |
| SRP133303 | PDGFRL | 5157 | RNAseq | 2.1065 | 0.0001 | |
| SRP159526 | PDGFRL | 5157 | RNAseq | 1.8822 | 0.0077 | |
| SRP219564 | PDGFRL | 5157 | RNAseq | 1.4972 | 0.1714 | |
| TCGA | PDGFRL | 5157 | RNAseq | -0.0275 | 0.9312 |
Upregulated datasets: 7; Downregulated datasets: 2.
Survival by PDGFRL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDGFRL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDGFRL | 5157 | 3 | 10 | 17 | |
| GSE20123 | PDGFRL | 5157 | 4 | 10 | 16 | |
| GSE43470 | PDGFRL | 5157 | 4 | 8 | 31 | |
| GSE46452 | PDGFRL | 5157 | 14 | 13 | 32 | |
| GSE47630 | PDGFRL | 5157 | 10 | 8 | 22 | |
| GSE54993 | PDGFRL | 5157 | 2 | 14 | 54 | |
| GSE54994 | PDGFRL | 5157 | 8 | 18 | 27 | |
| GSE60625 | PDGFRL | 5157 | 3 | 0 | 8 | |
| GSE74703 | PDGFRL | 5157 | 4 | 7 | 25 | |
| GSE74704 | PDGFRL | 5157 | 3 | 7 | 10 | |
| TCGA | PDGFRL | 5157 | 14 | 40 | 42 |
Total number of gains: 69; Total number of losses: 135; Total Number of normals: 284.
Somatic mutations of PDGFRL:
Generating mutation plots.
Highly correlated genes for PDGFRL:
Showing top 20/1084 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDGFRL | EFEMP2 | 0.750565 | 11 | 0 | 10 |
| PDGFRL | FCGR3A | 0.743836 | 3 | 0 | 3 |
| PDGFRL | TMEM263 | 0.740572 | 5 | 0 | 5 |
| PDGFRL | FSTL1 | 0.732656 | 12 | 0 | 12 |
| PDGFRL | EPDR1 | 0.727585 | 7 | 0 | 7 |
| PDGFRL | RAB34 | 0.723666 | 3 | 0 | 3 |
| PDGFRL | CNTN3 | 0.722681 | 3 | 0 | 3 |
| PDGFRL | SLC39A13 | 0.721441 | 6 | 0 | 6 |
| PDGFRL | SH3GL2 | 0.718825 | 4 | 0 | 4 |
| PDGFRL | FBN1 | 0.718485 | 10 | 0 | 10 |
| PDGFRL | ZNF382 | 0.715314 | 3 | 0 | 3 |
| PDGFRL | COL8A1 | 0.712914 | 9 | 0 | 9 |
| PDGFRL | GLT8D2 | 0.711553 | 11 | 0 | 9 |
| PDGFRL | FAM229B | 0.710167 | 4 | 0 | 4 |
| PDGFRL | RARRES2 | 0.709652 | 10 | 0 | 9 |
| PDGFRL | GDF6 | 0.708971 | 3 | 0 | 3 |
| PDGFRL | CTHRC1 | 0.708173 | 5 | 0 | 5 |
| PDGFRL | ISLR | 0.707114 | 12 | 0 | 11 |
| PDGFRL | LOXL3 | 0.706547 | 6 | 0 | 6 |
| PDGFRL | AEBP1 | 0.70246 | 12 | 0 | 11 |
For details and further investigation, click here
