| Full name: transcriptional adaptor 3 | Alias Symbol: FLJ20221|FLJ21329|ADA3|hADA3|NGG1 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 10474 | HGNC ID: HGNC:19422 | Ensembl Gene: ENSG00000171148 | OMIM ID: 602945 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TADA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TADA3 | 10474 | 215273_s_at | 0.0782 | 0.8711 | |
| GSE20347 | TADA3 | 10474 | 215273_s_at | -0.1596 | 0.2652 | |
| GSE23400 | TADA3 | 10474 | 215273_s_at | 0.0374 | 0.4299 | |
| GSE26886 | TADA3 | 10474 | 215273_s_at | 0.1153 | 0.5204 | |
| GSE29001 | TADA3 | 10474 | 215273_s_at | -0.0718 | 0.7572 | |
| GSE38129 | TADA3 | 10474 | 215273_s_at | -0.1344 | 0.1903 | |
| GSE45670 | TADA3 | 10474 | 215273_s_at | -0.0102 | 0.9440 | |
| GSE53622 | TADA3 | 10474 | 65936 | -0.3862 | 0.0000 | |
| GSE53624 | TADA3 | 10474 | 65936 | -0.1428 | 0.0022 | |
| GSE63941 | TADA3 | 10474 | 215273_s_at | -0.1612 | 0.7585 | |
| GSE77861 | TADA3 | 10474 | 215273_s_at | -0.0158 | 0.9558 | |
| GSE97050 | TADA3 | 10474 | A_23_P109821 | -0.0395 | 0.8989 | |
| SRP007169 | TADA3 | 10474 | RNAseq | -0.1254 | 0.7923 | |
| SRP008496 | TADA3 | 10474 | RNAseq | -0.1842 | 0.5177 | |
| SRP064894 | TADA3 | 10474 | RNAseq | 0.3414 | 0.2545 | |
| SRP133303 | TADA3 | 10474 | RNAseq | -0.0403 | 0.7932 | |
| SRP159526 | TADA3 | 10474 | RNAseq | -0.1301 | 0.5701 | |
| SRP193095 | TADA3 | 10474 | RNAseq | -0.2384 | 0.0522 | |
| SRP219564 | TADA3 | 10474 | RNAseq | -0.3303 | 0.3935 | |
| TCGA | TADA3 | 10474 | RNAseq | -0.0870 | 0.0619 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TADA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TADA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TADA3 | 10474 | 1 | 18 | 11 | |
| GSE20123 | TADA3 | 10474 | 1 | 18 | 11 | |
| GSE43470 | TADA3 | 10474 | 1 | 20 | 22 | |
| GSE46452 | TADA3 | 10474 | 2 | 17 | 40 | |
| GSE47630 | TADA3 | 10474 | 3 | 22 | 15 | |
| GSE54993 | TADA3 | 10474 | 6 | 1 | 63 | |
| GSE54994 | TADA3 | 10474 | 3 | 31 | 19 | |
| GSE60625 | TADA3 | 10474 | 5 | 0 | 6 | |
| GSE74703 | TADA3 | 10474 | 1 | 16 | 19 | |
| GSE74704 | TADA3 | 10474 | 1 | 11 | 8 | |
| TCGA | TADA3 | 10474 | 5 | 65 | 26 |
Total number of gains: 29; Total number of losses: 219; Total Number of normals: 240.
Somatic mutations of TADA3:
Generating mutation plots.
Highly correlated genes for TADA3:
Showing top 20/217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TADA3 | ASB7 | 0.806678 | 3 | 0 | 3 |
| TADA3 | CCND3 | 0.773612 | 3 | 0 | 3 |
| TADA3 | IFNAR1 | 0.766372 | 3 | 0 | 3 |
| TADA3 | PRADC1 | 0.748826 | 3 | 0 | 3 |
| TADA3 | LRTOMT | 0.743185 | 3 | 0 | 3 |
| TADA3 | SPNS1 | 0.742351 | 3 | 0 | 3 |
| TADA3 | WASF2 | 0.740143 | 3 | 0 | 3 |
| TADA3 | BRK1 | 0.73128 | 3 | 0 | 3 |
| TADA3 | TUBA1B | 0.728062 | 3 | 0 | 3 |
| TADA3 | FARSA | 0.727865 | 3 | 0 | 3 |
| TADA3 | PGAP2 | 0.726499 | 3 | 0 | 3 |
| TADA3 | HDDC3 | 0.724982 | 3 | 0 | 3 |
| TADA3 | PSME3 | 0.721637 | 4 | 0 | 4 |
| TADA3 | RUNDC1 | 0.708467 | 3 | 0 | 3 |
| TADA3 | EBF1 | 0.706779 | 3 | 0 | 3 |
| TADA3 | UQCR10 | 0.70479 | 3 | 0 | 3 |
| TADA3 | RNF40 | 0.70477 | 3 | 0 | 3 |
| TADA3 | STOML1 | 0.703242 | 4 | 0 | 3 |
| TADA3 | CRLF1 | 0.702591 | 3 | 0 | 3 |
| TADA3 | C20orf27 | 0.701678 | 3 | 0 | 3 |
For details and further investigation, click here
