| Full name: sec1 family domain containing 2 | Alias Symbol: STXBP1L1|FLJ39514 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 152579 | HGNC ID: HGNC:30676 | Ensembl Gene: ENSG00000184178 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SCFD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCFD2 | 152579 | 226923_at | -0.1690 | 0.6870 | |
| GSE26886 | SCFD2 | 152579 | 226923_at | 0.1320 | 0.5857 | |
| GSE45670 | SCFD2 | 152579 | 226923_at | -0.2577 | 0.0708 | |
| GSE53622 | SCFD2 | 152579 | 113681 | -0.1043 | 0.0919 | |
| GSE53624 | SCFD2 | 152579 | 113681 | -0.0890 | 0.1399 | |
| GSE63941 | SCFD2 | 152579 | 226923_at | -0.7702 | 0.1660 | |
| GSE77861 | SCFD2 | 152579 | 226923_at | -0.6869 | 0.0115 | |
| GSE97050 | SCFD2 | 152579 | A_23_P92543 | 0.3692 | 0.2785 | |
| SRP007169 | SCFD2 | 152579 | RNAseq | -0.9322 | 0.0520 | |
| SRP008496 | SCFD2 | 152579 | RNAseq | -0.7707 | 0.0075 | |
| SRP064894 | SCFD2 | 152579 | RNAseq | 0.0296 | 0.8714 | |
| SRP133303 | SCFD2 | 152579 | RNAseq | -0.1238 | 0.6047 | |
| SRP159526 | SCFD2 | 152579 | RNAseq | -0.2044 | 0.4539 | |
| SRP193095 | SCFD2 | 152579 | RNAseq | -0.4563 | 0.0003 | |
| SRP219564 | SCFD2 | 152579 | RNAseq | -0.0793 | 0.8269 | |
| TCGA | SCFD2 | 152579 | RNAseq | 0.0609 | 0.3610 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCFD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCFD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCFD2 | 152579 | 4 | 11 | 15 | |
| GSE20123 | SCFD2 | 152579 | 3 | 11 | 16 | |
| GSE43470 | SCFD2 | 152579 | 0 | 14 | 29 | |
| GSE46452 | SCFD2 | 152579 | 1 | 36 | 22 | |
| GSE47630 | SCFD2 | 152579 | 1 | 18 | 21 | |
| GSE54993 | SCFD2 | 152579 | 7 | 0 | 63 | |
| GSE54994 | SCFD2 | 152579 | 2 | 10 | 41 | |
| GSE60625 | SCFD2 | 152579 | 0 | 0 | 11 | |
| GSE74703 | SCFD2 | 152579 | 0 | 12 | 24 | |
| GSE74704 | SCFD2 | 152579 | 2 | 6 | 12 | |
| TCGA | SCFD2 | 152579 | 19 | 28 | 49 |
Total number of gains: 39; Total number of losses: 146; Total Number of normals: 303.
Somatic mutations of SCFD2:
Generating mutation plots.
Highly correlated genes for SCFD2:
Showing top 20/276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCFD2 | FBXO10 | 0.792766 | 3 | 0 | 3 |
| SCFD2 | NUMA1 | 0.754763 | 3 | 0 | 3 |
| SCFD2 | SHB | 0.725378 | 3 | 0 | 3 |
| SCFD2 | CLTA | 0.724681 | 3 | 0 | 3 |
| SCFD2 | CAMSAP1 | 0.723911 | 3 | 0 | 3 |
| SCFD2 | WDR26 | 0.714968 | 3 | 0 | 3 |
| SCFD2 | PEPD | 0.708432 | 3 | 0 | 3 |
| SCFD2 | ELMOD2 | 0.694152 | 3 | 0 | 3 |
| SCFD2 | UFL1 | 0.693696 | 3 | 0 | 3 |
| SCFD2 | TRAPPC8 | 0.692675 | 3 | 0 | 3 |
| SCFD2 | FAM200A | 0.691738 | 3 | 0 | 3 |
| SCFD2 | NFIA | 0.684501 | 3 | 0 | 3 |
| SCFD2 | PRKCH | 0.683518 | 3 | 0 | 3 |
| SCFD2 | STK19 | 0.682825 | 3 | 0 | 3 |
| SCFD2 | RBPJL | 0.682215 | 3 | 0 | 3 |
| SCFD2 | PLAA | 0.681844 | 4 | 0 | 3 |
| SCFD2 | GORASP1 | 0.680992 | 3 | 0 | 3 |
| SCFD2 | GNPTAB | 0.680407 | 3 | 0 | 3 |
| SCFD2 | KLHL9 | 0.675067 | 5 | 0 | 5 |
| SCFD2 | USP6NL | 0.674978 | 3 | 0 | 3 |
For details and further investigation, click here
