| Full name: deleted in lymphocytic leukemia 2 | Alias Symbol: LEU2|TRIM13OS|NCRNA00022|LINC00022|MIR15AHG | ||
| Type: non-coding RNA | Cytoband: 13q14.2 | ||
| Entrez ID: 8847 | HGNC ID: HGNC:13748 | Ensembl Gene: ENSG00000231607 | OMIM ID: 605766 |
| Drug and gene relationship at DGIdb | |||
Expression of DLEU2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLEU2 | 8847 | 216870_x_at | 1.3019 | 0.0754 | |
| GSE20347 | DLEU2 | 8847 | 216870_x_at | 0.4216 | 0.0488 | |
| GSE23400 | DLEU2 | 8847 | 216870_x_at | 0.2008 | 0.0000 | |
| GSE26886 | DLEU2 | 8847 | 216870_x_at | -0.2733 | 0.4665 | |
| GSE29001 | DLEU2 | 8847 | 216870_x_at | 0.5746 | 0.0219 | |
| GSE38129 | DLEU2 | 8847 | 216870_x_at | 0.5475 | 0.0373 | |
| GSE45670 | DLEU2 | 8847 | 1556821_x_at | 0.7374 | 0.0030 | |
| GSE53622 | DLEU2 | 8847 | 75411 | 0.7603 | 0.0000 | |
| GSE53624 | DLEU2 | 8847 | 59632 | 0.9332 | 0.0000 | |
| GSE63941 | DLEU2 | 8847 | 216870_x_at | 1.9859 | 0.0012 | |
| GSE77861 | DLEU2 | 8847 | 1556821_x_at | 0.5115 | 0.5027 | |
| SRP007169 | DLEU2 | 8847 | RNAseq | -1.0170 | 0.0417 | |
| SRP008496 | DLEU2 | 8847 | RNAseq | -0.1342 | 0.7260 | |
| SRP064894 | DLEU2 | 8847 | RNAseq | 0.7624 | 0.0053 | |
| SRP133303 | DLEU2 | 8847 | RNAseq | 0.6160 | 0.0177 | |
| SRP159526 | DLEU2 | 8847 | RNAseq | 1.0119 | 0.0031 | |
| SRP193095 | DLEU2 | 8847 | RNAseq | 0.1067 | 0.4016 | |
| SRP219564 | DLEU2 | 8847 | RNAseq | 0.3947 | 0.3550 | |
| TCGA | DLEU2 | 8847 | RNAseq | 0.9232 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by DLEU2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLEU2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLEU2 | 8847 | 1 | 13 | 16 | |
| GSE20123 | DLEU2 | 8847 | 1 | 12 | 17 | |
| GSE43470 | DLEU2 | 8847 | 3 | 13 | 27 | |
| GSE46452 | DLEU2 | 8847 | 0 | 32 | 27 | |
| GSE47630 | DLEU2 | 8847 | 2 | 27 | 11 | |
| GSE54993 | DLEU2 | 8847 | 12 | 2 | 56 | |
| GSE54994 | DLEU2 | 8847 | 2 | 14 | 37 | |
| GSE60625 | DLEU2 | 8847 | 0 | 3 | 8 | |
| GSE74703 | DLEU2 | 8847 | 3 | 10 | 23 | |
| GSE74704 | DLEU2 | 8847 | 0 | 9 | 11 | |
| TCGA | DLEU2 | 8847 | 9 | 37 | 50 |
Total number of gains: 33; Total number of losses: 172; Total Number of normals: 283.
Somatic mutations of DLEU2:
Generating mutation plots.
Highly correlated genes for DLEU2:
Showing top 20/428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLEU2 | GRHL2 | 0.675388 | 3 | 0 | 3 |
| DLEU2 | TFAP2A | 0.664122 | 3 | 0 | 3 |
| DLEU2 | DLEU2L | 0.654861 | 3 | 0 | 3 |
| DLEU2 | ALMS1 | 0.647629 | 4 | 0 | 4 |
| DLEU2 | DDX59 | 0.647555 | 3 | 0 | 3 |
| DLEU2 | GTSE1 | 0.646849 | 6 | 0 | 6 |
| DLEU2 | DEPDC1B | 0.646601 | 5 | 0 | 5 |
| DLEU2 | SUV39H2 | 0.645024 | 6 | 0 | 5 |
| DLEU2 | CEP85 | 0.643818 | 5 | 0 | 5 |
| DLEU2 | TMEM123 | 0.641953 | 3 | 0 | 3 |
| DLEU2 | XRCC2 | 0.638178 | 4 | 0 | 4 |
| DLEU2 | TTK | 0.63657 | 10 | 0 | 10 |
| DLEU2 | POLQ | 0.627675 | 8 | 0 | 7 |
| DLEU2 | TNRC6C-AS1 | 0.627607 | 3 | 0 | 3 |
| DLEU2 | OTUD6B | 0.627523 | 4 | 0 | 3 |
| DLEU2 | GTPBP8 | 0.624338 | 3 | 0 | 3 |
| DLEU2 | LRP8 | 0.624021 | 4 | 0 | 3 |
| DLEU2 | PABPC1L | 0.623788 | 4 | 0 | 3 |
| DLEU2 | HAUS2 | 0.623097 | 5 | 0 | 5 |
| DLEU2 | GAS2L3 | 0.622087 | 4 | 0 | 4 |
For details and further investigation, click here
