| Full name: metabolism of cobalamin associated A | Alias Symbol: cblA | ||
| Type: protein-coding gene | Cytoband: 4q31.21 | ||
| Entrez ID: 166785 | HGNC ID: HGNC:18871 | Ensembl Gene: ENSG00000151611 | OMIM ID: 607481 |
| Drug and gene relationship at DGIdb | |||
Expression of MMAA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MMAA | 166785 | 236347_at | 0.1957 | 0.7202 | |
| GSE26886 | MMAA | 166785 | 236347_at | -0.4766 | 0.1515 | |
| GSE45670 | MMAA | 166785 | 236347_at | 0.2347 | 0.1292 | |
| GSE53622 | MMAA | 166785 | 143797 | -0.3275 | 0.0007 | |
| GSE53624 | MMAA | 166785 | 2134 | -0.5764 | 0.0000 | |
| GSE63941 | MMAA | 166785 | 236347_at | -0.9557 | 0.0354 | |
| GSE77861 | MMAA | 166785 | 236347_at | -0.2537 | 0.0452 | |
| GSE97050 | MMAA | 166785 | A_33_P3405168 | 0.0815 | 0.7633 | |
| SRP007169 | MMAA | 166785 | RNAseq | -0.7224 | 0.0895 | |
| SRP008496 | MMAA | 166785 | RNAseq | -0.6106 | 0.0256 | |
| SRP064894 | MMAA | 166785 | RNAseq | -0.2564 | 0.0921 | |
| SRP133303 | MMAA | 166785 | RNAseq | -0.0590 | 0.6977 | |
| SRP159526 | MMAA | 166785 | RNAseq | -0.5754 | 0.0129 | |
| SRP193095 | MMAA | 166785 | RNAseq | -0.3582 | 0.0008 | |
| SRP219564 | MMAA | 166785 | RNAseq | -0.2776 | 0.3639 | |
| TCGA | MMAA | 166785 | RNAseq | -0.1527 | 0.0333 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MMAA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MMAA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMAA | 166785 | 0 | 12 | 18 | |
| GSE20123 | MMAA | 166785 | 0 | 12 | 18 | |
| GSE43470 | MMAA | 166785 | 0 | 13 | 30 | |
| GSE46452 | MMAA | 166785 | 1 | 36 | 22 | |
| GSE47630 | MMAA | 166785 | 0 | 22 | 18 | |
| GSE54993 | MMAA | 166785 | 10 | 0 | 60 | |
| GSE54994 | MMAA | 166785 | 2 | 11 | 40 | |
| GSE60625 | MMAA | 166785 | 0 | 1 | 10 | |
| GSE74703 | MMAA | 166785 | 0 | 11 | 25 | |
| GSE74704 | MMAA | 166785 | 0 | 7 | 13 | |
| TCGA | MMAA | 166785 | 12 | 32 | 52 |
Total number of gains: 25; Total number of losses: 157; Total Number of normals: 306.
Somatic mutations of MMAA:
Generating mutation plots.
Highly correlated genes for MMAA:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMAA | RNF8 | 0.733984 | 3 | 0 | 3 |
| MMAA | BROX | 0.726334 | 3 | 0 | 3 |
| MMAA | PUSL1 | 0.717633 | 3 | 0 | 3 |
| MMAA | SLC30A5 | 0.707507 | 3 | 0 | 3 |
| MMAA | MKRN2 | 0.702991 | 4 | 0 | 4 |
| MMAA | MTHFR | 0.702751 | 3 | 0 | 3 |
| MMAA | RAP1GDS1 | 0.697694 | 4 | 0 | 4 |
| MMAA | AGPAT3 | 0.691657 | 4 | 0 | 4 |
| MMAA | NTAN1 | 0.691141 | 3 | 0 | 3 |
| MMAA | MPP5 | 0.689319 | 3 | 0 | 3 |
| MMAA | SETD7 | 0.687233 | 3 | 0 | 3 |
| MMAA | CETN3 | 0.683173 | 3 | 0 | 3 |
| MMAA | UBE2F | 0.682759 | 3 | 0 | 3 |
| MMAA | SCYL3 | 0.682328 | 5 | 0 | 5 |
| MMAA | ZBTB1 | 0.681844 | 3 | 0 | 3 |
| MMAA | HBP1 | 0.677856 | 3 | 0 | 3 |
| MMAA | NCOA2 | 0.675015 | 4 | 0 | 4 |
| MMAA | RXRA | 0.671366 | 3 | 0 | 3 |
| MMAA | RETSAT | 0.670317 | 3 | 0 | 3 |
| MMAA | SLC9A8 | 0.669015 | 4 | 0 | 4 |
For details and further investigation, click here
