Full name: zinc finger CCHC-type containing 12	Alias Symbol: FLJ16123|SIZN|SIZN1|PNMA7A
Type: protein-coding gene	Cytoband: Xq24
Entrez ID: 170261	HGNC ID: HGNC:27273	Ensembl Gene: ENSG00000174460	OMIM ID: 300701
Drug and gene relationship at DGIdb
Screen Evidence: This gene has been idenfitied as a common driver in this paper. Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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Expression of ZCCHC12:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	ZCCHC12	170261	228715_at	0.0708	0.8651	Show
GSE26886	ZCCHC12	170261	228715_at	0.1114	0.2845	Show
GSE45670	ZCCHC12	170261	228715_at	0.0030	0.9809	Show
GSE53622	ZCCHC12	170261	99237	0.0142	0.9134	Show
GSE53624	ZCCHC12	170261	99237	0.4324	0.0001	Show
GSE63941	ZCCHC12	170261	228715_at	0.4578	0.4317	Show
GSE77861	ZCCHC12	170261	228715_at	-0.0470	0.7735	Show
SRP159526	ZCCHC12	170261	RNAseq	1.6836	0.0447	Show
TCGA	ZCCHC12	170261	RNAseq	-0.4085	0.4299	Show

Upregulated datasets: 1; Downregulated datasets: 0.  Download Data

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Survival by ZCCHC12 expression:

 

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Copy number change of ZCCHC12:

 

No record found for this gene.

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Somatic mutations of ZCCHC12:

 

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Highly correlated genes for ZCCHC12:

 

Showing all 19 correlated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
ZCCHC12	SOX8	0.736329	3	0	3
ZCCHC12	HTR1D	0.732683	3	0	3
ZCCHC12	PHEX	0.680927	3	0	3
ZCCHC12	SIX3	0.638349	4	0	3
ZCCHC12	LPL	0.634874	3	0	3
ZCCHC12	LBX2-AS1	0.606079	3	0	3
ZCCHC12	JPH3	0.594141	3	0	3
ZCCHC12	C3orf18	0.581856	4	0	3
ZCCHC12	NTRK1	0.577564	4	0	3
ZCCHC12	FAM117A	0.570543	3	0	3
ZCCHC12	TBC1D1	0.562531	4	0	3
ZCCHC12	CCDC151	0.561628	5	0	3
ZCCHC12	CACNA2D2	0.556279	6	0	4
ZCCHC12	NKD1	0.555962	5	0	3
ZCCHC12	YPEL1	0.553115	4	0	3
ZCCHC12	NPTX2	0.546355	4	0	3
ZCCHC12	ARL3	0.543167	4	0	3
ZCCHC12	ADD3-AS1	0.531827	4	0	3
ZCCHC12	NPY	0.522191	4	0	3

For details and further investigation, click here