| Full name: family with sequence similarity 172 member A | Alias Symbol: DKFZP564D172|Toupee | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 83989 | HGNC ID: HGNC:25365 | Ensembl Gene: ENSG00000113391 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM172A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM172A | 83989 | 212936_at | -0.9984 | 0.0247 | |
| GSE20347 | FAM172A | 83989 | 212936_at | -1.1457 | 0.0000 | |
| GSE23400 | FAM172A | 83989 | 212936_at | -0.3532 | 0.0000 | |
| GSE26886 | FAM172A | 83989 | 212936_at | -0.7530 | 0.0349 | |
| GSE29001 | FAM172A | 83989 | 212936_at | -0.7711 | 0.0255 | |
| GSE38129 | FAM172A | 83989 | 212936_at | -1.0267 | 0.0000 | |
| GSE45670 | FAM172A | 83989 | 212936_at | -0.9592 | 0.0000 | |
| GSE53622 | FAM172A | 83989 | 69248 | -1.0271 | 0.0000 | |
| GSE53624 | FAM172A | 83989 | 69248 | -1.0844 | 0.0000 | |
| GSE63941 | FAM172A | 83989 | 212936_at | -1.3386 | 0.0122 | |
| GSE77861 | FAM172A | 83989 | 212936_at | -0.9918 | 0.0033 | |
| GSE97050 | FAM172A | 83989 | A_24_P111912 | -0.7750 | 0.1189 | |
| SRP007169 | FAM172A | 83989 | RNAseq | 0.5575 | 0.3704 | |
| SRP008496 | FAM172A | 83989 | RNAseq | 0.3033 | 0.3926 | |
| SRP064894 | FAM172A | 83989 | RNAseq | -0.8204 | 0.0000 | |
| SRP133303 | FAM172A | 83989 | RNAseq | -0.3631 | 0.0122 | |
| SRP159526 | FAM172A | 83989 | RNAseq | -0.6701 | 0.0175 | |
| SRP193095 | FAM172A | 83989 | RNAseq | -0.8174 | 0.0000 | |
| SRP219564 | FAM172A | 83989 | RNAseq | -0.9444 | 0.0465 | |
| TCGA | FAM172A | 83989 | RNAseq | -0.2997 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by FAM172A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM172A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM172A | 83989 | 1 | 13 | 16 | |
| GSE20123 | FAM172A | 83989 | 1 | 13 | 16 | |
| GSE43470 | FAM172A | 83989 | 2 | 10 | 31 | |
| GSE46452 | FAM172A | 83989 | 1 | 27 | 31 | |
| GSE47630 | FAM172A | 83989 | 1 | 21 | 18 | |
| GSE54993 | FAM172A | 83989 | 8 | 1 | 61 | |
| GSE54994 | FAM172A | 83989 | 1 | 18 | 34 | |
| GSE60625 | FAM172A | 83989 | 0 | 0 | 11 | |
| GSE74703 | FAM172A | 83989 | 1 | 8 | 27 | |
| GSE74704 | FAM172A | 83989 | 1 | 7 | 12 | |
| TCGA | FAM172A | 83989 | 2 | 50 | 44 |
Total number of gains: 19; Total number of losses: 168; Total Number of normals: 301.
Somatic mutations of FAM172A:
Generating mutation plots.
Highly correlated genes for FAM172A:
Showing top 20/1593 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM172A | TMEM132C | 0.77685 | 3 | 0 | 3 |
| FAM172A | MBLAC2 | 0.765086 | 6 | 0 | 6 |
| FAM172A | FBXL3 | 0.764742 | 6 | 0 | 6 |
| FAM172A | TCEA3 | 0.751974 | 6 | 0 | 6 |
| FAM172A | ANGPTL1 | 0.748985 | 6 | 0 | 6 |
| FAM172A | PPM1L | 0.747268 | 7 | 0 | 7 |
| FAM172A | STK19 | 0.734074 | 4 | 0 | 4 |
| FAM172A | CNR1 | 0.730318 | 4 | 0 | 4 |
| FAM172A | GPD1L | 0.728985 | 11 | 0 | 11 |
| FAM172A | MRPL39 | 0.728684 | 3 | 0 | 3 |
| FAM172A | ZBTB47 | 0.727917 | 4 | 0 | 4 |
| FAM172A | CTTNBP2 | 0.72743 | 7 | 0 | 7 |
| FAM172A | GFRA1 | 0.725279 | 6 | 0 | 6 |
| FAM172A | ZCCHC9 | 0.724262 | 3 | 0 | 3 |
| FAM172A | CRBN | 0.723855 | 9 | 0 | 9 |
| FAM172A | PHF2 | 0.723681 | 3 | 0 | 3 |
| FAM172A | EIF4E3 | 0.720677 | 7 | 0 | 7 |
| FAM172A | MTMR10 | 0.718868 | 8 | 0 | 8 |
| FAM172A | RAB9B | 0.717613 | 6 | 0 | 5 |
| FAM172A | PREX2 | 0.716601 | 4 | 0 | 4 |
For details and further investigation, click here
