| Full name: RAB12, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18p11.22 | ||
| Entrez ID: 201475 | HGNC ID: HGNC:31332 | Ensembl Gene: ENSG00000206418 | OMIM ID: 616448 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB12 | 201475 | 239891_x_at | 0.1305 | 0.8292 | |
| GSE26886 | RAB12 | 201475 | 235059_at | -1.6039 | 0.0007 | |
| GSE45670 | RAB12 | 201475 | 235059_at | 0.1742 | 0.5232 | |
| GSE53622 | RAB12 | 201475 | 67207 | -0.2890 | 0.0005 | |
| GSE53624 | RAB12 | 201475 | 67207 | 0.1509 | 0.0204 | |
| GSE63941 | RAB12 | 201475 | 239891_x_at | 0.3092 | 0.2758 | |
| GSE77861 | RAB12 | 201475 | 239891_x_at | 0.1581 | 0.5307 | |
| GSE97050 | RAB12 | 201475 | A_24_P53353 | -0.2062 | 0.5470 | |
| SRP007169 | RAB12 | 201475 | RNAseq | 0.7509 | 0.1651 | |
| SRP008496 | RAB12 | 201475 | RNAseq | 0.6641 | 0.0373 | |
| SRP064894 | RAB12 | 201475 | RNAseq | 0.1878 | 0.4170 | |
| SRP133303 | RAB12 | 201475 | RNAseq | 0.3012 | 0.0687 | |
| SRP159526 | RAB12 | 201475 | RNAseq | 0.5638 | 0.0236 | |
| SRP193095 | RAB12 | 201475 | RNAseq | 0.2362 | 0.1213 | |
| SRP219564 | RAB12 | 201475 | RNAseq | -0.2980 | 0.3935 | |
| TCGA | RAB12 | 201475 | RNAseq | 0.1891 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RAB12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB12 | 201475 | 6 | 3 | 21 | |
| GSE20123 | RAB12 | 201475 | 6 | 3 | 21 | |
| GSE43470 | RAB12 | 201475 | 4 | 5 | 34 | |
| GSE46452 | RAB12 | 201475 | 3 | 21 | 35 | |
| GSE47630 | RAB12 | 201475 | 7 | 17 | 16 | |
| GSE54993 | RAB12 | 201475 | 6 | 3 | 61 | |
| GSE54994 | RAB12 | 201475 | 9 | 8 | 36 | |
| GSE60625 | RAB12 | 201475 | 0 | 4 | 7 | |
| GSE74703 | RAB12 | 201475 | 3 | 3 | 30 | |
| GSE74704 | RAB12 | 201475 | 4 | 2 | 14 | |
| TCGA | RAB12 | 201475 | 31 | 22 | 43 |
Total number of gains: 79; Total number of losses: 91; Total Number of normals: 318.
Somatic mutations of RAB12:
Generating mutation plots.
Highly correlated genes for RAB12:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB12 | PPP2R3A | 0.771694 | 3 | 0 | 3 |
| RAB12 | NDUFV2 | 0.758637 | 3 | 0 | 3 |
| RAB12 | BAK1 | 0.749754 | 3 | 0 | 3 |
| RAB12 | RFTN2 | 0.738401 | 3 | 0 | 3 |
| RAB12 | COPA | 0.733114 | 3 | 0 | 3 |
| RAB12 | NEDD8 | 0.732131 | 3 | 0 | 3 |
| RAB12 | KHNYN | 0.730705 | 4 | 0 | 3 |
| RAB12 | NUTF2 | 0.728326 | 3 | 0 | 3 |
| RAB12 | PSMC1 | 0.726269 | 3 | 0 | 3 |
| RAB12 | S1PR5 | 0.720611 | 3 | 0 | 3 |
| RAB12 | TMCC3 | 0.7187 | 3 | 0 | 3 |
| RAB12 | ATP6V1E1 | 0.717851 | 3 | 0 | 3 |
| RAB12 | STON2 | 0.706637 | 3 | 0 | 3 |
| RAB12 | PRKCI | 0.706357 | 3 | 0 | 3 |
| RAB12 | TINF2 | 0.698173 | 3 | 0 | 3 |
| RAB12 | RAB11FIP5 | 0.696621 | 3 | 0 | 3 |
| RAB12 | ZNF577 | 0.694097 | 3 | 0 | 3 |
| RAB12 | DRAP1 | 0.693016 | 3 | 0 | 3 |
| RAB12 | EIF2S1 | 0.692627 | 3 | 0 | 3 |
| RAB12 | TUBB3 | 0.689878 | 3 | 0 | 3 |
For details and further investigation, click here
