| Full name: rhotekin | Alias Symbol: B5 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 6242 | HGNC ID: HGNC:10466 | Ensembl Gene: ENSG00000114993 | OMIM ID: 602288 |
| Drug and gene relationship at DGIdb | |||
Expression of RTKN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTKN | 6242 | 225150_s_at | 1.0813 | 0.0309 | |
| GSE26886 | RTKN | 6242 | 225150_s_at | 1.2796 | 0.0000 | |
| GSE45670 | RTKN | 6242 | 225150_s_at | 0.9794 | 0.0007 | |
| GSE53622 | RTKN | 6242 | 13300 | 1.1052 | 0.0000 | |
| GSE53624 | RTKN | 6242 | 13300 | 1.0144 | 0.0000 | |
| GSE63941 | RTKN | 6242 | 225150_s_at | 1.6798 | 0.0058 | |
| GSE77861 | RTKN | 6242 | 225150_s_at | 1.2345 | 0.0010 | |
| GSE97050 | RTKN | 6242 | A_23_P120056 | 0.7136 | 0.1760 | |
| SRP007169 | RTKN | 6242 | RNAseq | 1.5496 | 0.0000 | |
| SRP008496 | RTKN | 6242 | RNAseq | 1.6723 | 0.0000 | |
| SRP064894 | RTKN | 6242 | RNAseq | 0.9833 | 0.0000 | |
| SRP133303 | RTKN | 6242 | RNAseq | 1.1674 | 0.0001 | |
| SRP159526 | RTKN | 6242 | RNAseq | 1.5128 | 0.0002 | |
| SRP193095 | RTKN | 6242 | RNAseq | 1.0660 | 0.0000 | |
| SRP219564 | RTKN | 6242 | RNAseq | 1.2573 | 0.0082 | |
| TCGA | RTKN | 6242 | RNAseq | 0.4152 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by RTKN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTKN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTKN | 6242 | 9 | 2 | 19 | |
| GSE20123 | RTKN | 6242 | 11 | 1 | 18 | |
| GSE43470 | RTKN | 6242 | 4 | 0 | 39 | |
| GSE46452 | RTKN | 6242 | 2 | 3 | 54 | |
| GSE47630 | RTKN | 6242 | 7 | 0 | 33 | |
| GSE54993 | RTKN | 6242 | 0 | 6 | 64 | |
| GSE54994 | RTKN | 6242 | 10 | 0 | 43 | |
| GSE60625 | RTKN | 6242 | 0 | 3 | 8 | |
| GSE74703 | RTKN | 6242 | 4 | 0 | 32 | |
| GSE74704 | RTKN | 6242 | 8 | 0 | 12 | |
| TCGA | RTKN | 6242 | 37 | 2 | 57 |
Total number of gains: 92; Total number of losses: 17; Total Number of normals: 379.
Somatic mutations of RTKN:
Generating mutation plots.
Highly correlated genes for RTKN:
Showing top 20/1969 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTKN | ITGB4 | 0.820366 | 8 | 0 | 8 |
| RTKN | AGRN | 0.805095 | 7 | 0 | 7 |
| RTKN | YWHAG | 0.798851 | 5 | 0 | 5 |
| RTKN | FYN | 0.792048 | 3 | 0 | 3 |
| RTKN | IFRD2 | 0.789223 | 3 | 0 | 3 |
| RTKN | SLC39A3 | 0.788573 | 4 | 0 | 4 |
| RTKN | ARPC1B | 0.785543 | 7 | 0 | 7 |
| RTKN | TMSB10 | 0.779018 | 7 | 0 | 7 |
| RTKN | FMNL2 | 0.776043 | 7 | 0 | 7 |
| RTKN | OSR2 | 0.774816 | 3 | 0 | 3 |
| RTKN | BRAT1 | 0.772932 | 7 | 0 | 7 |
| RTKN | PTK7 | 0.771705 | 7 | 0 | 7 |
| RTKN | LMNB2 | 0.769304 | 7 | 0 | 7 |
| RTKN | KIAA0930 | 0.763843 | 7 | 0 | 7 |
| RTKN | EBNA1BP2 | 0.763128 | 3 | 0 | 3 |
| RTKN | SUPT7L | 0.762994 | 4 | 0 | 4 |
| RTKN | DDX39A | 0.761999 | 8 | 0 | 8 |
| RTKN | CBFB | 0.76194 | 3 | 0 | 3 |
| RTKN | MOGS | 0.761066 | 8 | 0 | 8 |
| RTKN | CD276 | 0.760093 | 4 | 0 | 4 |
For details and further investigation, click here
