| Full name: cytokine receptor like factor 3 | Alias Symbol: CREME9|CYTOR4 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 51379 | HGNC ID: HGNC:17177 | Ensembl Gene: ENSG00000176390 | OMIM ID: 614853 |
| Drug and gene relationship at DGIdb | |||
Expression of CRLF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRLF3 | 51379 | 205474_at | -0.0970 | 0.8997 | |
| GSE20347 | CRLF3 | 51379 | 205474_at | -0.2706 | 0.0864 | |
| GSE23400 | CRLF3 | 51379 | 205474_at | -0.0793 | 0.3924 | |
| GSE26886 | CRLF3 | 51379 | 205474_at | -0.1596 | 0.4035 | |
| GSE29001 | CRLF3 | 51379 | 205474_at | -0.2525 | 0.1778 | |
| GSE38129 | CRLF3 | 51379 | 205474_at | 0.0158 | 0.9321 | |
| GSE45670 | CRLF3 | 51379 | 205474_at | 0.0912 | 0.5568 | |
| GSE53622 | CRLF3 | 51379 | 154876 | 0.0326 | 0.6227 | |
| GSE53624 | CRLF3 | 51379 | 154876 | -0.1457 | 0.0240 | |
| GSE63941 | CRLF3 | 51379 | 205474_at | 0.4064 | 0.2394 | |
| GSE77861 | CRLF3 | 51379 | 205474_at | -0.0343 | 0.9250 | |
| GSE97050 | CRLF3 | 51379 | A_24_P56894 | 0.0007 | 0.9975 | |
| SRP007169 | CRLF3 | 51379 | RNAseq | 0.4545 | 0.2469 | |
| SRP008496 | CRLF3 | 51379 | RNAseq | 0.0620 | 0.8364 | |
| SRP064894 | CRLF3 | 51379 | RNAseq | -0.5540 | 0.0382 | |
| SRP133303 | CRLF3 | 51379 | RNAseq | -0.1529 | 0.2689 | |
| SRP159526 | CRLF3 | 51379 | RNAseq | -0.3660 | 0.3163 | |
| SRP193095 | CRLF3 | 51379 | RNAseq | -0.3249 | 0.0004 | |
| SRP219564 | CRLF3 | 51379 | RNAseq | -0.6700 | 0.1688 | |
| TCGA | CRLF3 | 51379 | RNAseq | 0.2991 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRLF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRLF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRLF3 | 51379 | 7 | 2 | 21 | |
| GSE20123 | CRLF3 | 51379 | 8 | 2 | 20 | |
| GSE43470 | CRLF3 | 51379 | 0 | 1 | 42 | |
| GSE46452 | CRLF3 | 51379 | 33 | 1 | 25 | |
| GSE47630 | CRLF3 | 51379 | 7 | 1 | 32 | |
| GSE54993 | CRLF3 | 51379 | 2 | 3 | 65 | |
| GSE54994 | CRLF3 | 51379 | 7 | 6 | 40 | |
| GSE60625 | CRLF3 | 51379 | 4 | 0 | 7 | |
| GSE74703 | CRLF3 | 51379 | 0 | 1 | 35 | |
| GSE74704 | CRLF3 | 51379 | 5 | 2 | 13 | |
| TCGA | CRLF3 | 51379 | 19 | 11 | 66 |
Total number of gains: 92; Total number of losses: 30; Total Number of normals: 366.
Somatic mutations of CRLF3:
Generating mutation plots.
Highly correlated genes for CRLF3:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRLF3 | KCNK6 | 0.784875 | 3 | 0 | 3 |
| CRLF3 | ZMYM2 | 0.771048 | 4 | 0 | 4 |
| CRLF3 | RNGTT | 0.738454 | 3 | 0 | 3 |
| CRLF3 | RNF24 | 0.725178 | 3 | 0 | 3 |
| CRLF3 | CDK5R1 | 0.710763 | 6 | 0 | 5 |
| CRLF3 | PHKA1 | 0.694644 | 3 | 0 | 3 |
| CRLF3 | PSMD14 | 0.691175 | 3 | 0 | 3 |
| CRLF3 | CYP1A2 | 0.688525 | 3 | 0 | 3 |
| CRLF3 | TXNDC17 | 0.682898 | 3 | 0 | 3 |
| CRLF3 | TBC1D2 | 0.682215 | 4 | 0 | 3 |
| CRLF3 | GAPVD1 | 0.679403 | 4 | 0 | 4 |
| CRLF3 | HSPA4 | 0.671054 | 6 | 0 | 5 |
| CRLF3 | SOX7 | 0.669445 | 3 | 0 | 3 |
| CRLF3 | PREP | 0.669072 | 3 | 0 | 3 |
| CRLF3 | SCOC | 0.668708 | 3 | 0 | 3 |
| CRLF3 | PLA2G4A | 0.66791 | 4 | 0 | 3 |
| CRLF3 | TDRD3 | 0.665768 | 3 | 0 | 3 |
| CRLF3 | MKRN2 | 0.656832 | 3 | 0 | 3 |
| CRLF3 | SNRK | 0.653356 | 4 | 0 | 4 |
| CRLF3 | RELL2 | 0.652348 | 3 | 0 | 3 |
For details and further investigation, click here
