| Full name: phosphatidylinositol glycan anchor biosynthesis class W | Alias Symbol: Gwt1|FLJ37433 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 284098 | HGNC ID: HGNC:23213 | Ensembl Gene: ENSG00000277161 | OMIM ID: 610275 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PIGW:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIGW | 284098 | 1558292_s_at | 0.3446 | 0.4781 | |
| GSE26886 | PIGW | 284098 | 1558292_s_at | 0.3050 | 0.1683 | |
| GSE45670 | PIGW | 284098 | 1558292_s_at | 0.6229 | 0.0030 | |
| GSE53622 | PIGW | 284098 | 31915 | 0.6115 | 0.0000 | |
| GSE53624 | PIGW | 284098 | 31915 | 0.5400 | 0.0000 | |
| GSE63941 | PIGW | 284098 | 1558292_s_at | 0.3430 | 0.5177 | |
| GSE77861 | PIGW | 284098 | 1558292_s_at | 0.5222 | 0.1221 | |
| GSE97050 | PIGW | 284098 | A_23_P379794 | 0.4368 | 0.1822 | |
| SRP007169 | PIGW | 284098 | RNAseq | 1.5805 | 0.0007 | |
| SRP008496 | PIGW | 284098 | RNAseq | 1.3037 | 0.0004 | |
| SRP064894 | PIGW | 284098 | RNAseq | 0.5112 | 0.0597 | |
| SRP133303 | PIGW | 284098 | RNAseq | 0.6912 | 0.0008 | |
| SRP159526 | PIGW | 284098 | RNAseq | 0.7098 | 0.0140 | |
| SRP193095 | PIGW | 284098 | RNAseq | 0.2517 | 0.0387 | |
| SRP219564 | PIGW | 284098 | RNAseq | 0.3204 | 0.4435 | |
| TCGA | PIGW | 284098 | RNAseq | 0.3522 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PIGW expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIGW:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIGW | 284098 | 5 | 1 | 24 | |
| GSE20123 | PIGW | 284098 | 5 | 1 | 24 | |
| GSE43470 | PIGW | 284098 | 1 | 2 | 40 | |
| GSE46452 | PIGW | 284098 | 34 | 0 | 25 | |
| GSE47630 | PIGW | 284098 | 8 | 1 | 31 | |
| GSE54993 | PIGW | 284098 | 3 | 3 | 64 | |
| GSE54994 | PIGW | 284098 | 8 | 6 | 39 | |
| GSE60625 | PIGW | 284098 | 4 | 0 | 7 | |
| GSE74703 | PIGW | 284098 | 1 | 1 | 34 | |
| GSE74704 | PIGW | 284098 | 3 | 1 | 16 | |
| TCGA | PIGW | 284098 | 20 | 9 | 67 |
Total number of gains: 92; Total number of losses: 25; Total Number of normals: 371.
Somatic mutations of PIGW:
Generating mutation plots.
Highly correlated genes for PIGW:
Showing top 20/799 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIGW | OSBPL3 | 0.710003 | 3 | 0 | 3 |
| PIGW | NXT2 | 0.706308 | 4 | 0 | 4 |
| PIGW | CCT6A | 0.69735 | 3 | 0 | 3 |
| PIGW | FANCD2 | 0.695373 | 6 | 0 | 6 |
| PIGW | TPMT | 0.691645 | 3 | 0 | 3 |
| PIGW | ADAM17 | 0.687084 | 7 | 0 | 7 |
| PIGW | TMEM167A | 0.687048 | 3 | 0 | 3 |
| PIGW | LRP8 | 0.68533 | 4 | 0 | 4 |
| PIGW | ARNTL2 | 0.6808 | 3 | 0 | 3 |
| PIGW | TBX1 | 0.680003 | 3 | 0 | 3 |
| PIGW | ATP11A | 0.679384 | 3 | 0 | 3 |
| PIGW | RRM2 | 0.675914 | 6 | 0 | 6 |
| PIGW | RGS20 | 0.673298 | 3 | 0 | 3 |
| PIGW | FAM89A | 0.671727 | 3 | 0 | 3 |
| PIGW | SHCBP1 | 0.670425 | 8 | 0 | 6 |
| PIGW | LRRC59 | 0.667937 | 5 | 0 | 4 |
| PIGW | KIF14 | 0.667864 | 6 | 0 | 6 |
| PIGW | RAN | 0.667363 | 6 | 0 | 5 |
| PIGW | KPNA2 | 0.665595 | 6 | 0 | 5 |
| PIGW | TPM3 | 0.664887 | 4 | 0 | 3 |
For details and further investigation, click here
